8068期

最新文章

• US-China trade conflict threatens biomedical collaboration AI翻译
  作者：Du, Yuwang
  作者单位：Guangxi Medical University
• Sequence diversity lost in early pregnancy AI翻译
  作者：Arnadottir, Gudny A.; Jonsson, Hakon; Hartwig, Tanja Schlaikjaer; Gruhn, Jennifer R.; Moller, Peter Loof; Gylfason, Arnaldur; Westergaard, David; Chan, Andrew Chi-Ho; Oddsson, Asmundur; Stefansdottir, Lilja; le Roux, Louise; Steinthorsdottir, Valgerdur; Moore, Kristjan H. Swerford; Olafsson, Sigurgeir; Olason, Pall I.; Eggertsson, Hannes P.; Halldorsson, Gisli H.; Walters, G. Bragi; Stefansson, Hreinn; Gudjonsson, Sigurjon A.; Palsson, Gunnar; Jensson, Brynjar O.; Fridriksdottir, Run; Petersen, Jesper Friis; Helgason, Agnar; Norddahl, Gudmundur L.; Rohde, Palle Duun; Saemundsdottir, Jona; Magnusson, Olafur Th.; Halldorsson, Bjarni V.; Bliddal, Sofie; Banasik, Karina; Gudbjartsson, Daniel F.; Nyegaard, Mette; Sulem, Patrick; Thorsteinsdottir, Unnur; Hoffmann, Eva R.; Nielsen, Henriette Svarre; Stefansson, Kari
  作者单位：Decode Genetics; University of Copenhagen; University of Copenhagen; Aalborg University; University of Copenhagen; Copenhagen University Hospital; Reykjavik University; University of Iceland; Statens Serum Institut; University of Iceland; University of Copenhagen
  摘要：Every generation, the human genome is shuffled during meiosis and a single fertilized egg gives rise to all of the cells of the body(1). Meiotic errors leading to chromosomal abnormalities are known causes of pregnancy loss(2,3), but genetic aetiologies of euploid pregnancy loss remain largely unexplained(4). Here we characterize sequence diversity in early pregnancy loss through whole-genome sequencing of 1,007 fetal samples and 934 parental samples from 467 trios affected by pregnancy loss (...
• Coordination environments of Pt single-atom catalysts from NMR signatures AI翻译
  作者：Koppe, Jonas; Yakimov, Alexander V.; Gioffre, Domenico; Usteri, Marc-Eduard; Vosegaard, Thomas; Pintacuda, Guido; Lesage, Anne; Pell, Andrew J.; Mitchell, Sharon; Perez-Ramirez, Javier; Coperet, Christophe
  作者单位：Universite Claude Bernard Lyon 1; Ecole Normale Superieure de Lyon (ENS de LYON); Centre National de la Recherche Scientifique (CNRS); Swiss Federal Institutes of Technology Domain; ETH Zurich; Aarhus University; Aarhus University
  摘要：Supported metal catalysts that integrate atomically dispersed species with controlled structures lie at the forefront of catalytic materials design, offering exceptional control over reactivity and high metal utilization, approaching the precision of molecular systems1, 2-3. However, accurately resolving the local metal coordination environments remains challenging, hindering the advancement of structure-activity relationships needed to optimize their design for diverse applications1,2. Althou...
• Light-triggered regionally controlled n-doping of organic semiconductors AI翻译
  作者：Wang, Xin-Yi; Ding, Yi-Fan; Zhang, Xiao-Yan; Zhou, Yang-Yang; Pan, Chen-Kai; Li, Yuan-He; Liu, Nai-Fu; Yao, Ze-Fan; Chen, Yong-Shi; Xie, Zhi-Hao; Huang, Yi-Fan; Xu, Yu-Chun; Wu, Hao-Tian; Huang, Chun-Xi; Xiong, Miao; Ding, Li; Yu, Zi-Di; Li, Qi-Yi; Zheng, Yu-Qing; Wang, Jie-Yu; Pei, Jian
  作者单位：Peking University; Peking University
  摘要：Doping is a primary method to modulate the electrical properties of semiconductors, enabling the fabrication of various homojunctions/heterojunctions and complex devices1, 2, 3, 4, 5, 6, 7-8. For organic semiconductors (OSCs), the electrical performance has been extensively improved by developing doping methods and dopants9, 10, 11, 12-13. However, compared with the state-of-the-art spatial resolution of inorganic semiconductor fabrication processes, OSCs lag far behind, limiting the construct...
• Single-cell transcriptomics reveal how root tissues adapt to soil stress AI翻译
  作者：Zhu, Mingyuan; Hsu, Che-Wei; Ogorek, Lucas L. Peralta; Taylor, Isaiah W.; La Cavera, Salvatore; Oliveira, Dyoni M.; Verma, Lokesh; Mehra, Poonam; Mijar, Medhavinee; Sadanandom, Ari; Perez-Cota, Fernando; Boerjan, Wout; Nolan, Trevor M.; Bennett, Malcolm J.; Benfey, Philip N.; Pandey, Bipin K.
  作者单位：Duke University; Howard Hughes Medical Institute; Duke University; University of Nottingham; University of Nottingham; Ghent University; Flanders Institute for Biotechnology (VIB); Durham University; California Institute of Technology
  摘要：Land plants thrive in soils showing vastly different properties and environmental stresses1. Root systems can adapt to contrasting soil conditions and stresses, yet how their responses are programmed at the individual cell scale remains unclear. Using single-cell RNA sequencing and spatial transcriptomic approaches, we showed major expression changes in outer root cell types when comparing the single-cell transcriptomes of rice roots grown in gel versus soil conditions. These tissue-specific t...
• A pangenome reference of wild and cultivated rice AI翻译
  作者：Guo, Dongling; Li, Yan; Lu, Hengyun; Zhao, Yan; Kurata, Nori; Wei, Xinghua; Wang, Ahong; Wang, Yongchun; Zhan, Qilin; Fan, Danlin; Zhou, Congcong; Lu, Yiqi; Tian, Qilin; Weng, Qijun; Feng, Qi; Huang, Tao; Zhang, Lei; Gu, Zhoulin; Wang, Changsheng; Wang, Ziqun; Wang, Zixuan; Huang, Xuehui; Zhao, Qiang; Han, Bin
  作者单位：Chinese Academy of Sciences; Center for Excellence in Molecular Plant Sciences, CAS; Chinese Academy of Sciences; University of Chinese Academy of Sciences, CAS; Research Organization of Information & Systems (ROIS); National Institute of Genetics (NIG) - Japan; Research Organization of Information & Systems (ROIS); National Institute of Genetics (NIG) - Japan; Chinese Academy of Agricultural Sciences; China National Rice Research Institute, CAAS; Shanghai Normal University
  摘要：Oryza rufipogon, the wild progenitor of Asian cultivated rice Oryza sativa, is an important resource for rice breeding1. Here we present a wild-cultivated rice pangenome based on 145 chromosome-level assemblies, comprising 129 genetically diverse O. rufipogon accessions and 16 diverse varieties of O. sativa. This pangenome contains 3.87 Gb of sequences that are absent from the O. sativa ssp. japonica cv. Nipponbare reference genome. We captured alternate assemblies that include heterozygous in...
• Light detectors made from perovskite crystals see in full colour AI翻译
  作者：Nie, Shuming; Gruev, Viktor
  作者单位：University of Illinois System; University of Illinois Urbana-Champaign
• Why the Royal Greenwich Observatory was chosen to mark zero degrees longitude AI翻译
  作者：[Anonymous]
• Is a monster web of ocean currents headed for collapse? The race is on to find out AI翻译
  作者：Kalvelage, Tim
• Reply to: On the effects of fault alignment on slip stability AI翻译
  作者：Lee, Jaeseok; Tsai, Victor C.; Hirth, Greg; Chatterjee, Avigyan; Trugman, Daniel T.
  作者单位：Brown University; Nevada System of Higher Education (NSHE); University of Nevada Reno