8081期

最新文章

• How billions of hacked mosquitoes and a vaccine could beat the deadly dengue virus AI翻译
  作者：Pinto, Lucila
• Mitochondrial origins of the pressure to sleep AI翻译
  作者：Sarnataro, Raffaele; Velasco, Cecilia D.; Monaco, Nicholas; Kempf, Anissa; Miesenbock, Gero
  作者单位：University of Oxford; University of Basel
  摘要：To gain a comprehensive, unbiased perspective on molecular changes in the brain that may underlie the need for sleep, we have characterized the transcriptomes of single cells isolated from rested and sleep-deprived flies. Here we report that transcripts upregulated after sleep deprivation, in sleep-control neurons projecting to the dorsal fan-shaped body1,2 (dFBNs) but not ubiquitously in the brain, encode almost exclusively proteins with roles in mitochondrial respiration and ATP synthesis. T...
• Bioelectronic implants built from rolled-up stretchy circuits AI翻译
  作者：Lee, Hyunjin; Kim, Dae-Hyeong
  作者单位：Institute for Basic Science - Korea (IBS); Seoul National University (SNU)
• Controversial New Alzheimer's Drugs Offer Hope-But at a High Cost AI翻译
  作者：Seegert, Liz
• When AI rejects your grant proposal: algorithms are helping to make funding decisions AI翻译
  作者：Adam, David
• Addressing the safety of next-generation batteries AI翻译
  作者：Yang, Chuanbo; Singh, Avtar; Pu, Xiaofei; Mallarapu, Anudeep; Smith, Kandler; Keyser, Matt; Haberman, Michael R.; Khani, Hadi; Misztal, Pawel; Spray, Ryan; Ezekoye, Ofodike A.; Finegan, Donal P.
  作者单位：United States Department of Energy (DOE); National Renewable Energy Laboratory - USA; University of Texas System; University of Texas Austin; University of Texas System; University of Texas Austin; University of Texas System; University of Texas Austin; Exponent
  摘要：Owing to increasing demand for low-cost energy storage with secure material supply chains, the battery community is approaching a pivotal shift beyond conventional lithium-ion (Li-ion) towards next-generation cells. Technologies that include alkali-metal anodes, solid electrolytes and earth-abundant materials such as sodium (Na) and sulfur (S) are reaching commercialization in cells. The abuse tolerance and thermal runaway hazards of such technologies diverge from conventional Li-ion cells. Co...
• Structural and functional characterization of human sweet taste receptor AI翻译
  作者：Shi, Zongjun; Xu, Weixiu; Wu, Lijie; Yue, Xiaolei; Liu, Shenhui; Ding, Wei; Zhang, Jinyi; Meng, Bing; Zhao, Lianghao; Liu, Xiaoyan; Liu, Junlin; Liu, Zhi-Jie; Hua, Tian
  作者单位：ShanghaiTech University; ShanghaiTech University; Chinese Academy of Sciences; Institute of Physics, CAS
  摘要：Sweet taste perception influences dietary choices and metabolic health. The human sweet taste receptor, a class C G-protein-coupled receptor (GPCR) heterodimer composed of TAS1R2 and TAS1R3 (refs. 1,2), senses a wide range of sweet compounds-including natural sugars, artificial sweeteners and sweet proteins-and affects metabolic regulation beyond taste. However, the lack of three-dimensional structures hinders our understanding of its precise working mechanism. Here we present cryo-electron mi...
• 'Brain dial' turns food consumption on or off in mice AI翻译
  作者：Heidt, Amanda
• The Vexing Promise of New Blood Tests for Alzheimer's AI翻译
  作者：Willyard, Cassandra
• 'LIPSTICK ON A PIG': HOW TO HANDLE PEER-REVIEW BULLIES AI翻译
  作者：Zimmer, Katarina