2025

最新文章

• The peer-review crisis: how to fix an overloaded system AI翻译
  作者：Adam, David
• Taurine from tumour niche drives glycolysis to promote leukaemogenesis AI翻译
  作者：Sharma, Sonali; Rodems, Benjamin J.; Baker, Cameron D.; Kaszuba, Christina M.; Franco, Edgardo I.; Smith, Bradley R.; Ito, Takashi; Swovick, Kyle; Welle, Kevin; Zhang, Yi; Rock, Philip; Chaves, Francisco A.; Ghaemmaghami, Sina; Calvi, Laura M.; Ganguly, Archan; Burack, W. Richard; Becker, Michael W.; Liesveld, Jane L.; Brookes, Paul S.; Munger, Joshua C.; Jordan, Craig T.; Ashton, John M.; Bajaj, Jeevisha
  作者单位：University of Rochester; University of Rochester; University of Rochester; University of Rochester; University of Rochester; Fukui Prefectural University; University of Rochester; University of Rochester; University of Rochester; University of Rochester; University of Rochester; University of Rochester; University of Colorado System; University of Colorado Anschutz Medical Campus
  摘要：Signals from the microenvironment are known to be critical for development, stem cell self-renewal and oncogenic progression. Although some niche-driven signals that promote cancer progression have been identified1, 2, 3, 4-5, concerted efforts to map disease-relevant microenvironmental ligands of cancer stem cell receptors have been lacking. Here, we use temporal single-cell RNA-sequencing (scRNA-seq) to identify molecular cues from the bone marrow stromal niche that engage leukaemia stem-enr...
• Conserve marine migratory species to protect ecological links between land and sea AI翻译
  作者：Lassalle, Geraldine; Lambert, Patrick; Darnaude, Audrey M.; de Almeida, Pedro Raposo
  作者单位：INRAE; University of Evora
• Reply to: Inconclusive proof of ferroelectricity in peptide-VDF ribbons AI翻译
  作者：Yang, Yang; Sai, Hiroaki; Egner, Simon A.; Qiu, Ruomeng; Palmer, Liam C.; Stupp, Samuel I.
  作者单位：Northwestern University; Northwestern University; Northwestern University; Northwestern University; Northwestern University
• DeepMind and OpenAI models solve maths problems at level of top students AI翻译
  作者：Castelvecchi, Davide
  摘要：For the first time, large language models performed on a par with gold medallists in global maths contests.
• Overcome threats to renewable energy through skilful statecraft AI翻译
  作者：Chandrashekeran, Sangeetha; Fish, Adam; Thurbon, Elizabeth; Sovacool, Benjamin K.
  作者单位：University of Melbourne; University of New South Wales Sydney; University of Sussex
• Magnon spectroscopy in the electron microscope AI翻译
  作者：Kepaptsoglou, Demie; Castellanos-Reyes, Jose Angel; Kerrigan, Adam; Alves do Nascimento, Julio; Zeiger, Paul M.; El Hajraoui, Khalil; Idrobo, Juan Carlos; Mendis, Budhika G.; Bergman, Anders; Lazarov, Vlado K.; Rusz, Jan; Ramasse, Quentin M.
  作者单位：University of York - UK; University of York - UK; Uppsala University; University of Washington; University of Washington Seattle; United States Department of Energy (DOE); Pacific Northwest National Laboratory; Durham University; University of Leeds; University of Leeds
  摘要：The miniaturization of transistors is approaching its limits owing to challenges in heat management and information transfer speed1. To overcome these obstacles, emerging technologies such as spintronics2 are being developed, which make use of the electron's spin as well as its charge. Local phenomena at interfaces or structural defects will greatly influence the efficiency of spin-based devices, making the ability to study spin-wave propagation at the nanoscale and atomic scale a key challeng...
• Neuronal transfer of mitochondria to tumour cells promotes cancer spread AI翻译
  作者：Singh, Anand K.; Pan, Yuan
  作者单位：University of Texas System; UTMD Anderson Cancer Center; University of Texas System; UTMD Anderson Cancer Center
• Major expansion in the human niche preceded out of Africa dispersal AI翻译
  作者：Hallett, Emily Y.; Leonardi, Michela; Cerasoni, Jacopo Niccolo; Will, Manuel; Beyer, Robert; Krapp, Mario; Kandel, Andrew W.; Manica, Andrea; Scerri, Eleanor M. L.
  作者单位：Loyola University Chicago; Max Planck Society; University of Cambridge; Natural History Museum London; Loyola University Chicago; Eberhard Karls University of Tubingen; University of Johannesburg; Eberhard Karls University of Tubingen; University of Malta; University of Cologne
  摘要：All contemporary Eurasians trace most of their ancestry to a small population that dispersed out of Africa about 50,000 years ago (ka)1, 2, 3, 4, 5, 6, 7, 8-9. By contrast, fossil evidence attests to earlier migrations out of Africa10, 11, 12, 13, 14-15. These lines of evidence can only be reconciled if early dispersals made little to no genetic contribution to the later, major wave. A key question therefore concerns what factors facilitated the successful later dispersal that led to long-term...
• Don't train medical AI on patients' data without their knowledge AI翻译
  作者：Banerjee, Toral; Lin, Rongyu; Shi, Mengyuan
  作者单位：Clark University; Emory University