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作者：Woodley, Lucas; See, Chung Yi; Nunes, Ashley
作者单位：Harvard University
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作者：Zhu, Kun; Reid, Obadiah; Rangan, Sylvie; Wang, Li; Li, Jingbai; Durai, Kevin Antony Jesu; Zhou, Kang; Javed, Nasir; Kasaei, Leila; Yang, Chongqing; Li, Mingxing; Sun, Yue; Tan, Kui; Cotlet, Mircea; Liu, Yi; Feldman, Leonard C.; O'Carroll, Deirdre M.; Zhu, Kai; Li, Jing
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作者：Klavans, Jeremy M.; DiNezio, Pedro N.; Clement, Amy C.; Deser, Clara; Shanahan, Timothy M.; Cane, Mark A.
作者单位：University of Colorado System; University of Colorado Boulder; University of Miami; National Center Atmospheric Research (NCAR) - USA; University of Texas System; University of Texas Austin; Columbia University
摘要：The Pacific decadal oscillation (PDO)-the leading pattern of climate variability driving changes over the North Pacific and surrounding continents-is now thought to be generated by processes internal to the climate system1,2. According to this paradigm, the characteristic, irregular oscillations of the PDO arise from a collection of mechanisms involving ocean and atmosphere interactions in the North and tropical Pacific3, 4-5. Recent variations in the coupled ocean-atmosphere system, such as t...
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作者：Morez Jacobs, Adeline; Irish, Joel D.; Cooke, Ashley; Anastasiadou, Kyriaki; Barrington, Christopher; Gilardet, Alexandre; Kelly, Monica; Silva, Marina; Speidel, Leo; Tait, Frankie; Williams, Mia; Brucato, Nicolas; Ricaut, Francois-Xavier; Wilkinson, Caroline; Madgwick, Richard; Holt, Emily; Nederbragt, Alexandra J.; Inglis, Edward; Hajdinjak, Mateja; Skoglund, Pontus; Girdland-Flink, Linus
作者单位：Liverpool John Moores University; Francis Crick Institute; Francis Crick Institute; Swedish Museum of Natural History; University of London; University College London; Centre National de la Recherche Scientifique (CNRS); Universite de Toulouse; Universite Toulouse III - Paul Sabatier; Institut de Recherche pour le Developpement (IRD); Universite Federale Toulouse Midi-Pyrenees (ComUE); Institut National Polytechnique de Toulouse; Liverpool John Moores University; Cardiff University; Cardiff University; University of Aberdeen; University of Padua; RIKEN; University of Reading
摘要：Ancient Egyptian society flourished for millennia, reaching its peak during the Dynastic Period (approximately 3150-30 bce). However, owing to poor DNA preservation, questions about regional interconnectivity over time have not been addressed because whole-genome sequencing has not yet been possible. Here we sequenced a 2x coverage whole genome from an adult male Egyptian excavated at Nuwayrat (Nuerat, (sic)). Radiocarbon dated to 2855-2570 cal. bce, he lived a few centuries after Egyptian uni...
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作者：Tollefson, Jeff
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作者：Abram, Nerilie J.; Purich, Ariaan; England, Matthew H.; Mccormack, Felicity S.; Strugnell, Jan M.; Bergstrom, Dana M.; Vance, Tessa R.; Stal, Tobias; Wienecke, Barbara; Heil, Petra; Doddridge, Edward W.; Sallee, Jean-Baptiste; Williams, Thomas J.; Reading, Anya M.; Mackintosh, Andrew; Reese, Ronja; Winkelmann, Ricarda; Klose, Ann Kristin; Boyd, Philip W.; Chown, Steven L.; Robinson, Sharon A.
作者单位：Australian National University; Australian National University; Australian National University; Monash University; Monash University; University of New South Wales Sydney; University of New South Wales Sydney; James Cook University; James Cook University; James Cook University; University of Wollongong; University of Johannesburg; University of Tasmania; University of Tasmania; Australian Antarctic Division; University of Tasmania; University of Tasmania; Swiss Federal Institutes of Technology Domain; Swiss Federal Institute for Forest, Snow & Landscape Research; Centre National de la Recherche Scientifique (CNRS); Institut de Recherche pour le Developpement (IRD); Museum National d'Histoire Naturelle (MNHN); Sorbonne Universite; Northumbria University; Max Planck Society; Potsdam Institut fur Klimafolgenforschung; University of Potsdam; University of Wollongong
摘要：Human-caused climate change worsens with every increment of additional warming, although some impacts can develop abruptly. The potential for abrupt changes is far less understood in the Antarctic compared with the Arctic, but evidence is emerging for rapid, interacting and sometimes self-perpetuating changes in the Antarctic environment. A regime shift has reduced Antarctic sea-ice extent far below its natural variability of past centuries, and in some respects is more abrupt, non-linear and ...
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作者：Miranda, Antonio M. A.; McAllan, Liam; Mazzei, Guianfranco; Andrew, Ivan; Davies, Iona; Ertugrul, Meryem; Kenkre, Julia; Kudo, Hiromi; Carrelha, Joana; Patel, Bhavik; Newton, Sophie; Zhang, Weihua; Pollard, Alice; Cross, Amy; McCallion, Oliver; Jang, Mikyung; Choi, Ka Lok; Brown, Scarlett; Rasool, Yasmin; Adamo, Marco; Elkalaawy, Mohamed; Jenkinson, Andrew; Mohammadi, Borzoueh; Hashemi, Majid; Goldin, Robert; Game, Laurence; Hester, Joanna; Issa, Fadi; Ryan, Dylan G.; Ortega, Patricia; Ahmed, Ahmed R.; Batterham, Rachel L.; Chambers, John C.; Kooner, Jaspal S.; Baranasic, Damir; Noseda, Michela; Tan, Tricia; Scott, William R.
作者单位：Imperial College London; Imperial College London; Imperial College London; Imperial College London; Imperial College London; University of Oxford; Imperial College London; University of Oxford; University of London; University College London; University College London Hospitals NHS Foundation Trust; University of Cambridge; Imperial College London; University of London; University College London; King's College London; University College London Hospitals NHS Foundation Trust; Imperial College London; Nanyang Technological University; Imperial College London; Rudjer Boskovic Institute
摘要：Weight loss significantly improves metabolic and cardiovascular health in people with obesity1, 2-3. The remodelling of adipose tissue (AT) is central to these varied and important clinical effects4. However, surprisingly little is known about the underlying mechanisms, presenting a barrier to treatment advances. Here we report a spatially resolved single-nucleus atlas (comprising 171,247 cells from 70 people) investigating the cell types, molecular events and regulatory factors that reshape h...
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作者：Wang, Zhaoquan; Lipshutz, Allie; Martinez de la Torre, Celia; Trzeciak, Alissa J.; Liu, Zong-Lin; Miranda, Isabella C.; Lazarov, Tomi; Codo, Ana C.; Romero-Pichardo, Jesus E.; Nair, Achuth; Schild, Tanya; Saitz Rojas, Waleska; Saavedra, Pedro H. V.; Baako, Ann K.; Fadojutimi, Kelvin; Downey, Michael S.; Geissmann, Frederic; Faraco, Giuseppe; Gan, Li; Etchegaray, Jon Iker; Lucas, Christopher D.; Tanasova, Marina; Parkhurst, Christopher N.; Zeng, Melody Y.; Keshari, Kayvan R.; Perry, Justin S. A.
作者单位：Memorial Sloan Kettering Cancer Center; Cornell University; Weill Cornell Medicine; Memorial Sloan Kettering Cancer Center; Memorial Sloan Kettering Cancer Center; Cornell University; Weill Cornell Medicine; Memorial Sloan Kettering Cancer Center; Northeastern University; Cornell University; Weill Cornell Medicine; Cornell University; Weill Cornell Medicine; Cornell University; Weill Cornell Medicine; Washington University (WUSTL); Oklahoma Medical Research Foundation; University of Edinburgh; Michigan Technological University; Michigan Technological University; Cornell University; Weill Cornell Medicine; Cornell University; Weill Cornell Medicine
摘要：Despite the success of fructose as a low-cost food additive, epidemiological evidence suggests that high fructose consumption during pregnancy or adolescence is associated with disrupted neurodevelopment1, 2-3. An essential step in appropriate mammalian neurodevelopment is the phagocytic elimination of newly formed neurons by microglia, the resident professional phagocyte of the central nervous system4. Whether high fructose consumption in early life affects microglial phagocytosis and whether...
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作者：McKeown-Green, Amy; Dionne, Jennifer A.
作者单位：Stanford University; Stanford University
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作者：[Anonymous]
