Proceedings of the National Academy of Sciences of the United States of America

最新文章

• Physics- informed deep learning for stochastic particle dynamics estimation AI翻译
  作者：Zhang, Yongyu; Zhu, Junlun; Xie, Hao; He, Yan
  作者单位：Tsinghua University; Chinese Academy of Sciences; Institute of Physics, CAS
  摘要：Single- particle tracking has enabled quantitative studies of complex systems, providing nanometer localization precision and millisecond temporal resolution in heterogeneous environments. However, at micro- or nanometer scales, probe dynamics become inherently stochastic due to Brownian motion and complex interactions, leading to varied diffusion behaviors. Typically, analysis of such trajectory data involves certain moving- window operation and assumes the existence of some pseudo-steady sta...
• Cas9-mediated gene-editing frequency in microalgae is doubled by harnessing the interaction between importin α and phytopathogenic NLSs AI翻译
  作者：Le, Trang Thi; Choi, Hong Il; Kim, Ji Won; Yun, Jin - Ho; Lee, Yoon Hyeok; Jeon, Eun Jung; Kwon, Kil Koang; Cho, Dae - Hyun; Choi, Dong - Yun; Park, Su - Bin; Yoon, Hyang Ran; Lee, Jeongmi; Sim, Eun Jeong; Lee, Yong Jae; Kim, Hee - Sik
  作者单位：Korea Research Institute of Bioscience & Biotechnology (KRIBB); University of Science & Technology (UST); Sungkyunkwan University (SKKU); Korea Research Institute of Bioscience & Biotechnology (KRIBB); Korea Research Institute of Bioscience & Biotechnology (KRIBB); Korea Research Institute of Bioscience & Biotechnology (KRIBB); University of Science & Technology (UST)
  摘要：Pathogen-derived nuclear localization signals (NLSs) enable vigorous nuclear invasion in the host by the virulence proteins harboring them. Herein, inspired by the robust nuclear import mechanism, we show that NLSs originating from the plant infection-associated Agrobacterium proteins VirD2 and VirE2 can be incorporated into the Cas9 system as efficient nuclear delivery enhancers, thereby improving the low gene-editing frequency in a model microalga, Chlamydomonas reinhardtii, caused by poor n...
• Listen for a change? A longitudinal field experiment on listening's potential to enhance persuasion AI翻译
  作者：Santoro, Erik; Broockman, David E.; Kalla, Joshua L.; Porat, Roni
  作者单位：Columbia University; University of California System; University of California Berkeley; Yale University; Hebrew University of Jerusalem; Hebrew University of Jerusalem
  摘要：Scholars and practitioners widely posit that listening to other people enhances efforts to persuade them. Listening may enhance persuasion by promoting cognitive processing, reducing defensiveness, and improving perceptions of the persuader. However, empirical tests of this widely theorized hypothesis are surprisingly scarce. We review the case for and against this hypothesis, arguing previous research has not sufficiently attended to reasons why listening may not enhance persuasion. We test t...
• Band asymmetry-driven nonreciprocal electronic transport in a helimagnetic semimetal α- EuP3 (vol 122, e2405839122, 2025) AI翻译
  作者：Mayo, Alex Hiro; Deaconu, Darius-Alexandru; Masuda, Hidetoshi; Nii, Yoichi; Takahashi, Hidefumi; Belosludov, Rodion Vladimirovich; Ishiwata, Shintaro; Bahramy, Mohammad Saeed; Onose, Yoshinori
• Turbulent mixing controls fixation of growing antagonisticpopulations AI翻译
  作者：Bauermann, Jonathan; Benzi, Roberto; Nelson, David R.; Shankar, Suraj; Toschi, Federico
  作者单位：Harvard University; North University of China; University of Rome Tor Vergata; University of Rome Tor Vergata; University of Michigan System; University of Michigan; Eindhoven University of Technology; Consiglio Nazionale delle Ricerche (CNR)
  摘要：Unlike coffee and cream that homogenize when stirred, growing micro-organisms(e.g., bacteria, baker's yeast) can actively kill each other and avoid mixing. How dosuch antagonistic interactions impact the growth and survival of competing strains,while being spatially advected by turbulent flows? By using numerical simulations of acontinuum model, we study the dynamics of two antagonistic strains that are dispersedby incompressible turbulent flows in two spatial dimensions. A key parameter is th...
• Interrogating nucleotide sequences with AI to understand codon usage patterns AI翻译
  作者：Elazar, Assaf; Mathew, Steve; Babu, M. Madan
  作者单位：St Jude Children's Research Hospital; Vellore Institute of Technology (VIT); VIT Vellore
• A deep learning-enabled smart garment for accurate and versatile monitoring of sleep conditions in daily life AI翻译
  作者：Tang, Chenyu; Yi, Wentian; Xu, Muzi; Jin, Yuxuan; Zhang, Zibo; Chen, Xuhang; Liao, Caizhi; Kang, Mengtian; Gao, Shuo; Smielewski, Peter; Occhipinti, Luigi G.
  作者单位：University of Cambridge; University of Cambridge; University of Cambridge; Capital Medical University; Beihang University
  摘要：In wearable smart systems, continuous monitoring and accurate classification of dif-ferent sleep- related conditions are critical for enhancing sleep quality and preventing sleep- related chronic conditions. However, the requirements for device-skin coupling quality in electrophysiological sleep monitoring systems hinder the comfort and reli-ability of night wearing. Here, we report a washable, skin- compatible smart garment sleep monitoring system that captures local skin strain signals under...
• A limitation lifted: A conditional knockdown system reveals essential roles for Polo- like kinase and Aurora kinase 1 in Trypanosoma cruzi cell division AI翻译
  作者：Wiedeman, Justin; Harrison, Ruby; Etheridge, Ronald Drew
  作者单位：University System of Georgia; University of Georgia; University System of Georgia; University of Georgia
  摘要：While advances in genome editing technologies have simplified gene disruption in many organisms, the study of essential genes requires development of conditional disruption or knockdown systems that are not available in most organisms. Such is the case for Trypanosoma cruzi, a parasite that causes Chagas disease, a severely neglected tropical disease endemic to Latin America that is often fatal. Our knowledge of the identity of essential genes and their functions in T. cruzi has been severely ...
• Mycorrhiza increases plant diversity and soil carbon storage in grasslands AI翻译
  作者：Zhang, Entao; Wang, Yang; Crowther, Thomas W.; Sun, Weicheng; Chen, Shiping; Zhou, Daowei; Shangguan, Zhouping; Huang, Jianhui; He, Jin - Sheng; Wang, Yanfen; Sheng, Jiandong; Tang, Lisong; Li, Xinrong; Dong, Ming; Wu, Yan; Hu, Shuijin; Bai, Yongfei; Yu, Guirui
  作者单位：Chinese Academy of Sciences; Institute of Botany, CAS; Chinese Academy of Sciences; University of Chinese Academy of Sciences, CAS; Swiss Federal Institutes of Technology Domain; ETH Zurich; Chinese Academy of Sciences; Northeast Institute of Geography & Agroecology, CAS; Northwest A&F University - China; Chinese Academy of Sciences; University of Chinese Academy of Sciences, CAS; Lanzhou University; Lanzhou University; Peking University; Xinjiang Agricultural University; Chinese Academy of Sciences; Xinjiang Institute of Ecology & Geography, CAS; Chinese Academy of Sciences; Hangzhou Normal University; Chinese Academy of Sciences; Chengdu Institute of Biology, CAS; North Carolina State University; Chinese Academy of Sciences; Institute of Geographic Sciences & Natural Resources Research, CAS
  摘要：Experimental studies have shown that symbiotic relationships between arbuscular mycorrhizal (AM) fungi and host plants can regulate soil organic carbon (SOC) storage. Although the impacts of mycorrhiza are highly context- dependent, it remains unclear how these effects vary across broad spatial scales. Based on data from 2296 field sites across grassland ecosystems of China, here we show that mycorrhizal fungi symbiosis enhances SOC storage in the topsoil and subsoil through increasing plant d...
• Touching the classical scaling in penetrative convection AI翻译
  作者：Ouyang, Zhen; Wang, Qi; Li, Kai; Wen, Baole; Ding, Zijing
  作者单位：Harbin Institute of Technology; Southern University of Science & Technology; Chinese Academy of Sciences; Institute of Mechanics, CAS; New York Institute Technology
  摘要：The Cassini missions have identified the tiger stripes on Enceladus as the source of both thermal emission and plume jets. The hot spots in the tiger stripes are highly localized, and the plumes suggest active hydrothermal processes within the subglacial ocean of Enceladus. However, understanding the mechanism responsible for the heat anomalies in the tiger stripes remains a challenge. About 60 y ago, geoscientist George Veronis proposed a model for cold water oceans, along with the classical ...