Nature

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• Optical nonlinearities in excess of 500 through sublattice reconstruction AI翻译
  作者：Chen, Jiaye; Liu, Chang; Xi, Shibo; Tan, Shengdong; He, Qian; Liang, Liangliang; Liu, Xiaogang
  作者单位：National University of Singapore; Xiamen University; Agency for Science Technology & Research (A*STAR); National University of Singapore; Agency for Science Technology & Research (A*STAR); A*STAR - Institute of Materials Research & Engineering (IMRE); National University of Singapore
  摘要：The ability of materials to respond to stimuli with significant optical nonlinearity is crucial for technological advancement and innovation1, 2-3. Although photon-avalanche upconversion nanomaterials with nonlinearities exceeding 60 have been developed, further enhancement remains challenging4, 5-6. Here we present a method to increase photon-avalanche nonlinearity beyond 500 by reconstructing the sublattice and extending the avalanche network. We demonstrate that lutetium substitution in the...
• Global terrestrial nitrogen fixation and its modification by agriculture AI翻译
  作者：Reis Ely, Carla R.; Perakis, Steven S.; Cleveland, Cory C.; Menge, Duncan N. L.; Reed, Sasha C.; Taylor, Benton N.; Batterman, Sarah A.; Clark, Christopher M.; Crews, Timothy E.; Dynarski, Katherine A.; Gei, Maga; Gundale, Michael J.; Herridge, David F.; Jovan, Sarah E.; Kou-Giesbrecht, Sian; Peoples, Mark B.; Piipponen, Johannes; Rodriguez-Caballero, Emilio; Salmon, Verity G.; Soper, Fiona M.; Staccone, Anika P.; Weber, Bettina; Williams, Christopher A.; Wurzburger, Nina
  作者单位：Oregon State University; United States Department of the Interior; United States Geological Survey; University of Montana System; University of Montana; Columbia University; United States Department of the Interior; United States Geological Survey; Harvard University; Cary Institute of Ecosystem Studies; University of Leeds; Smithsonian Institution; Smithsonian Tropical Research Institute; United States Environmental Protection Agency; Swedish University of Agricultural Sciences; University of New England; United States Department of Agriculture (USDA); United States Forest Service; Dalhousie University; Commonwealth Scientific & Industrial Research Organisation (CSIRO); CSIRO Agriculture & Food; Aalto University; Universidad de Almeria; Universidad de Almeria; Max Planck Society; United States Department of Energy (DOE); Oak Ridge National Laboratory; United States Department of Energy (DOE); Oak Ridge National Laboratory; McGill University; McGill University; University of Graz; Clark University; University System of Georgia; University of Georgia; Oak Ridge Associated Universities; United States Department of Energy (DOE); Oak Ridge Institute for Science & Education
  摘要：Biological nitrogen fixation (BNF) is the largest natural source of new nitrogen (N) that supports terrestrial productivity1,2, yet estimates of global terrestrial BNF remain highly uncertain3,4. Here we show that this uncertainty is partly because of sampling bias, as field BNF measurements in natural terrestrial ecosystems occur where N fixers are 17 times more prevalent than their mean abundances worldwide. To correct this bias, we develop new estimates of global terrestrial BNF by upscalin...
• In vivo screen of Plasmodium targets for mosquito-based malaria control AI翻译
  作者：Probst, Alexandra S.; Paton, Douglas G.; Appetecchia, Federico; Bopp, Selina; Adams, Kelsey L.; Rinvee, Tasneem A.; Pou, Sovitj; Winter, Rolf; Du, Esrah W.; Yahiya, Sabrina; Vidoudez, Charles; Singh, Naresh; Rodrigues, Janneth; Castaneda-Casado, Pablo; Tammaro, Chiara; Chen, Daisy; Godinez-Macias, Karla P.; Jaramillo, Jasmine L.; Poce, Giovanna; Rubal, Michael J.; Nilsen, Aaron; Winzeler, Elizabeth A.; Baum, Jake; Burrows, Jeremy N.; Riscoe, Michael K.; Wirth, Dyann F.; Catteruccia, Flaminia
  作者单位：Harvard University; Harvard T.H. Chan School of Public Health; Imperial College London; GlaxoSmithKline; Glaxosmithkline United Kingdom; Sapienza University Rome; University of California System; University of California San Diego; Southwest Research Institute; Oregon Health & Science University; University of New South Wales Sydney; Harvard University; Massachusetts Institute of Technology (MIT); Broad Institute; Howard Hughes Medical Institute; University System of Georgia; University of Georgia
  摘要：The decline in malaria deaths has recently stalled owing to several factors, including the widespread resistance of Anopheles vectors to the insecticides used in long-lasting insecticide-treated nets (LLINs)1,2. One way to mitigate insecticide resistance is to directly kill parasites during their mosquito-stage of development by incorporating antiparasitic compounds into LLINs. This strategy can prevent onward parasite transmission even when insecticides lose efficacy3,4. Here, we performed an...
• Bring science into business schools to train the leaders of tomorrow AI翻译
  作者：Agarwala, Matthew
  作者单位：University of Sussex
• Range extender mediates long-distance enhancer activity AI翻译
  作者：Bower, Grace; Hollingsworth, Ethan W.; Jacinto, Sandra H.; Alcantara, Joshua A.; Clock, Benjamin; Cao, Kaitlyn; Liu, Mandy; Dziulko, Adam; Alcaina-Caro, Ana; Xu, Qianlan; Skowronska-Krawczyk, Dorota; Lopez-Rios, Javier; Dickel, Diane E.; Bardet, Anais F.; Pennacchio, Len A.; Visel, Axel; Kvon, Evgeny Z.
  作者单位：University of California System; University of California Irvine; University of California System; University of California Irvine; United States Department of Energy (DOE); Lawrence Berkeley National Laboratory; Consejo Superior de Investigaciones Cientificas (CSIC); Universidad Pablo de Olavide; CSIC - Andalusian Center for Developmental Biology (CABD); University of California System; University of California Irvine; University of California System; University of California Irvine; University of California System; University of California Irvine; Universidad Loyola Andalucia; Centre National de la Recherche Scientifique (CNRS); CNRS - National Institute for Biology (INSB); Institut National de la Sante et de la Recherche Medicale (Inserm); Universites de Strasbourg Etablissements Associes; Universite de Strasbourg; United States Department of Energy (DOE); Lawrence Berkeley National Laboratory; University of California System; University of California Berkeley; University of California System; University of California Merced
  摘要：Although most mammalian transcriptional enhancers regulate their cognate promoters over distances of tens of kilobases, some enhancers act over distances in the megabase range1. The sequence features that enable such long-distance enhancer-promoter interactions remain unclear. Here we used in vivo enhancer-replacement experiments at the mouse Shh locus to show that short- and medium-range limb enhancers cannot initiate gene expression at long-distance range. We identify a cis-acting element, r...
• Systems consolidation reorganizes hippocampal engram circuitry AI翻译
  作者：Ko, Sangyoon Y.; Rong, Yiming; Ramsaran, Adam I.; Chen, Xiaoyu; Rashid, Asim J.; Mocle, Andrew J.; Dhaliwal, Jagroop; Awasthi, Ankit; Guskjolen, Axel; Josselyn, Sheena A.; Frankland, Paul W.
  作者单位：University of Toronto; Hospital for Sick Children (SickKids); University of Toronto; University of Toronto; University of Toronto; University of Toronto; Canadian Institute for Advanced Research (CIFAR)
  摘要：Episodic memories-high-fidelity memories for events that depend initially on the hippocampus-do not maintain their precision in perpetuity. One benefit of this time-dependent loss of precision is the emergence of event-linked gist memories that may be used to guide future behaviour in new but related situations (that is, generalization)1, 2-3. Models of systems consolidation propose that memory reorganization accompanies this loss of memory precision1,4; however, the locus of this reorganizati...
• World's most porous sponges: intricate carbon-trapping powders hit the market AI翻译
  作者：Sanderson, Katharine
  摘要：Invented more than three decades ago, metal-organic frameworks are becoming commercial materials. By Katharine Sanderson
• Mitochondrial molecule has unexpected role in tissue healing AI翻译
  作者：Chakrabarty, Ram P.; Chandel, Navdeep S.
  作者单位：Northwestern University; Feinberg School of Medicine; Northwestern University; Feinberg School of Medicine; Chan Zuckerberg Initiative (CZI)
• Arrests of scientists over smuggled samples add to US border anxiety AI翻译
  作者：Basilio, Humberto
  摘要：Nature talks to specialists about the cases and what to watch out for when transporting lab materials.
• Address Colombia's brain-health crisis AI翻译
  作者：Cardona, Juan F.; Trujillo-Llano, Catalina; Miller, Johnny; Ibanez, Agustin
  作者单位：Universidad del Valle; Universitat Greifswald; Greifswald Medical School; Trinity College Dublin; Universidad Adolfo Ibanez