Nature

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• Prevention of respiratory virus transmission by resident memory CD8+ T cells AI翻译
  作者：Uddback, Ida; Michalets, Sarah E.; Saha, Ananya; Mattingly, Cameron; Kost, Kirsten N.; Williams, M. Elliott; Lawrence, Laurel A.; Hicks, Sakeenah L.; Lowen, Anice C.; Ahmed, Hasan; Thomsen, Allan R.; Russell, Charles J.; Scharer, Christopher D.; Boss, Jeremy M.; Koelle, Katia; Antia, Rustom; Christensen, Jan P.; Kohlmeier, Jacob E.
  作者单位：Emory University; University of Copenhagen; Emory University; St Jude Children's Research Hospital
  摘要：An ideal vaccine both attenuates virus growth and disease in infected individuals and reduces the spread of infections in the population, thereby generating herd immunity. Although this strategy has proved successful by generating humoral immunity to measles, yellow fever and polio, many respiratory viruses evolve to evade pre-existing antibodies(1). One approach for improving the breadth of antiviral immunity against escape variants is through the generation of memory T cells in the respirato...
• Research institutions must share knowledge of cyberattacks AI翻译
  作者：[Anonymous]
• Leading US particle-physics lab faces uncertain future AI翻译
  作者：Garisto, Dan
• Intermediate conformations of CD4-bound HIV-1 Env heterotrimers ( vol 623, pg 1026, 2023) AI翻译
  作者：Dam, Kim-Marie A.; Fan, Chengcheng; Yang, Zhi; Bjorkman, Pamela J.
• Japan's drug-delay dilemma AI翻译
  作者：Namba, Mira; Kaneda, Yudai; Ozaki, Akihiko; Tanimoto, Tetsuya
  作者单位：Keio University; Hokkaido University
• Country-specific net-zero strategies of the pulp and paper industry AI翻译
  作者：Dai, Min; Sun, Mingxing; Chen, Bin; Shi, Lei; Jin, Mingzhou; Man, Yi; Liang, Ziyang; de Almeida, Cecilia Maria Villas Boas; Li, Jiashuo; Zhang, Pengfei; Chiu, Anthony S. F.; Xu, Ming; Yu, Huajun; Meng, Jing; Wang, Yutao
  作者单位：Fudan University; Fudan University; Chinese Academy of Sciences; Institute of Geographic Sciences & Natural Resources Research, CAS; Nanchang University; University of Tennessee System; University of Tennessee Knoxville; South China University of Technology; Universidade Paulista; Shandong University; De La Salle University; Tsinghua University; University of London; University College London; Fudan University; Fudan University
  摘要：The pulp and paper industry is an important contributor to global greenhouse gas emissions1,2. Country-specific strategies are essential for the industry to achieve net-zero emissions by 2050, given its vast heterogeneities across countries3,4. Here we develop a comprehensive bottom-up assessment of net greenhouse gas emissions of the domestic paper-related sectors for 30 major countries from 1961 to 2019-about 3.2% of global anthropogenic greenhouse gas emissions from the same period5-and exp...
• A glacier's 'memory' is fading because of climate change AI翻译
  作者：[Anonymous]
• 7-Dehydrocholesterol dictates ferroptosis sensitivity AI翻译
  作者：Li, Yaxu; Ran, Qiao; Duan, Qiuhui; Jin, Jiali; Wang, Yanjin; Yu, Lei; Wang, Chaojie; Zhu, Zhenyun; Chen, Xin; Weng, Linjun; Li, Zan; Wang, Jia; Wu, Qi; Wang, Hui; Tian, Hongling; Song, Sihui; Shan, Zezhi; Zhai, Qiwei; Qin, Huanlong; Chen, Shili; Fang, Lan; Yin, Huiyong; Zhou, Hu; Jiang, Xuejun; Wang, Ping
  作者单位：Tongji University; Tongji University; Chinese Academy of Sciences; Shanghai Institute of Materia Medica, CAS; Chinese Academy of Sciences; Shanghai Institute of Nutrition & Health, CAS; University of Chinese Academy of Sciences, CAS; Chinese Academy of Sciences; Center for Excellence in Molecular Cell Science, CAS; University of Chinese Academy of Sciences, CAS; Shanghai Jiao Tong University; City University of Hong Kong; Memorial Sloan Kettering Cancer Center
  摘要：Ferroptosis, a form of regulated cell death that is driven by iron-dependent phospholipid peroxidation, has been implicated in multiple diseases, including cancer1-3, degenerative disorders4 and organ ischaemia-reperfusion injury (IRI)5,6. Here, using genome-wide CRISPR-Cas9 screening, we identified that the enzymes involved in distal cholesterol biosynthesis have pivotal yet opposing roles in regulating ferroptosis through dictating the level of 7-dehydrocholesterol (7-DHC)-an intermediate me...
• No 'easy' weight loss: don't overlook the social cost of anti-obesity drugs AI翻译
  作者：Brewis, Alexandra; Trainer, Sarah
  作者单位：Arizona State University; Arizona State University-Tempe; Arizona State University; Arizona State University-Tempe; Seattle University
• Clinical trials: Japan's opt-out policy raises risks of adverse drug responses AI翻译
  作者：Namba, Mira; Kaneda, Yudai; Ozaki, Akihiko; Tanimoto, Tetsuya
  作者单位：Keio University; Hokkaido University
  摘要：Letter to the Editor