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作者:Mallapaty, Smriti
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作者:Tacon, Dave
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作者:Hoch, K. K. W.; Rowland, M.; Petrus, S.; Nasedkin, E.; Ingebretsen, C.; Kammerer, J.; Perrin, M.; D'Orazi, V.; Balmer, W. O.; Barman, T.; Bonnefoy, M.; Chauvin, G.; Chen, C.; De Rosa, R. J.; Girard, J.; Gonzales, E.; Kenworthy, M.; Konopacky, Q. M.; Macintosh, B.; Moran, S. E.; Morley, C. V.; Palma-Bifani, P.; Pueyo, L.; Ren, B.; Rickman, E.; Ruffio, J. -b.; Theissen, C. A.; Ward-Duong, K.; Zhang, Y.
作者单位:Space Telescope Science Institute; University of Texas System; University of Texas Austin; National Aeronautics & Space Administration (NASA); NASA Goddard Space Flight Center; Max Planck Society; Trinity College Dublin; Johns Hopkins University; European Southern Observatory; University of Padua; University of Arizona; Communaute Universite Grenoble Alpes; Universite Grenoble Alpes (UGA); European Southern Observatory; California State University System; San Francisco State University; Leiden University; Leiden University - Excl LUMC; University of California System; University of California San Diego; University of California System; University of California Santa Cruz; University of California System; University of California Santa Cruz; Universite Cote d'Azur; Observatoire de la Cote d'Azur; Centre National de la Recherche Scientifique (CNRS); Universite PSL; Observatoire de Paris; Sorbonne Universite; Universite Paris Cite; Space Telescope Science Institute; Smith College; California Institute of Technology
摘要:Young exoplanets provide an important link between understanding planet formation and atmospheric evolution1. Direct imaging spectroscopy allows us to infer the properties of young, wide-orbit, giant planets with high signal-to-noise ratio. This allows us to compare this young population with exoplanets characterized by transmission spectroscopy, which has indirectly revealed the presence of clouds2, 3-4, photochemistry5 and a diversity of atmospheric compositions6,7. Direct detections have al...
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作者:Ahart, Jenna
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作者:Brazil, Rachel
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作者:Callaway, Ewen
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作者:Kobrin, Bryce; Schuster, Thomas; Yao, Norman Y.
作者单位:University of California System; University of California Berkeley; Alphabet Inc.; Google Incorporated; California Institute of Technology; Harvard University
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作者:Meghdari, Ali
作者单位:Islamic Azad University
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作者:Kilgard, Michael P.; Epperson, Joseph D.; Adehunoluwa, Emmanuel A.; Swank, Chad; Porter, Amy L.; Pruitt, David T.; Gallaway, Holle L.; Stevens, Christi; Gillespie, Jaime; Arnold, Dannae; Powers, Mark B.; Hamilton, Rita G.; Naftalis, Richard C.; Foreman, Michael L.; Wigginton, Jane G.; Hays, Seth A.; Rennaker, Robert L.
作者单位:University of Texas System; University of Texas Dallas; University of Texas System; University of Texas Dallas; University of Texas System; University of Texas Dallas; Baylor University Medical Center; Baylor Scott & White Health; Baylor University Medical Center; Baylor University; Baylor University Medical Center; Baylor University; Baylor University Medical Center; Baylor University
摘要:Decades of research have demonstrated that recovery from serious neurological injury will require synergistic therapeutic approaches. Rewiring spared neural circuits after injury is a long-standing goal of neurorehabilitation1,2. We hypothesized that combining intensive, progressive, task-focused training with real-time closed-loop vagus nerve stimulation (CLV) to enhance synaptic plasticity3 could increase strength, expand range of motion and improve hand function in people with chronic, inco...
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作者:Goncalves, Renata L. S.; Wang, Zeqiu Branden; Riveros, Jillian K.; Parlakgul, Gunes; Inouye, Karen E.; Lee, Grace Yankun; Fu, Xiaorong; Saksi, Jani; Rosique, Clement; Hui, Sheng Tony; Coll, Mar; Arruda, Ana Paula; Burgess, Shawn C.; Graupera, Isabel; Hotamisligil, Goekhan S.
作者单位:Harvard University; Harvard T.H. Chan School of Public Health; University of Texas System; University of Texas Southwestern Medical Center; CIBER - Centro de Investigacion Biomedica en Red; CIBEREHD; University of Barcelona; Hospital Clinic de Barcelona; Harvard University; Massachusetts Institute of Technology (MIT); Broad Institute; University of California System; University of California Berkeley
摘要:Mitochondrial reactive oxygen species (mROS) are central to physiology1,2. Excess mROS production has been associated with several disease states2,3; however, the precise sources, regulation and mechanism of generation in vivo remain unclear, which limits translational efforts. Here we show that in obesity, hepatic coenzyme Q (CoQ) synthesis is impaired, which increases the CoQH2 to CoQ (CoQH2/CoQ) ratio and drives excessive mROS production through reverse electron transport (RET) from site IQ...