Nature

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• Biological age surges in survivors of childhood cancer AI翻译
  作者：[Anonymous]
  摘要：People who survived paediatric cancers age faster and are at higher risk of early death.
• An exoplanet is wrapped in glory AI翻译
  作者：[Anonymous]
  摘要：Astronomers spot the first planet outside the Solar System to boast a phenomenon reminiscent of a rainbow.
• Frans de Waal (1948-2024) Obituary AI翻译
  作者：Whiten, Andrew
  作者单位：University of St Andrews
• Methane emission from a cool brown dwarf AI翻译
  作者：Faherty, Jacqueline K.; Burningham, Ben; Gagne, Jonathan; Suarez, Genaro; Vos, Johanna M.; Merchan, Sherelyn Alejandro; Morley, Caroline V.; Rowland, Melanie; Lacy, Brianna; Kiman, Rocio; Caselden, Dan; Kirkpatrick, J. Davy; Meisner, Aaron; Schneider, Adam C.; Kuchner, Marc Jason; Gagliuffi, Daniella Carolina Bardalez; Beichman, Charles; Eisenhardt, Peter; Gelino, Christopher R.; Gharib-Nezhad, Ehsan; Gonzales, Eileen; Marocco, Federico; Rothermich, Austin James; Whiteford, Niall
  作者单位：American Museum of Natural History (AMNH); University of Hertfordshire; Universite de Montreal; Trinity College Dublin; City University of New York (CUNY) System; Hunter College (CUNY); University of Texas System; University of Texas Austin; California Institute of Technology; California Institute of Technology; National Aeronautics & Space Administration (NASA); NASA Goddard Space Flight Center; Amherst College; California Institute of Technology; National Aeronautics & Space Administration (NASA); NASA Jet Propulsion Laboratory (JPL); National Aeronautics & Space Administration (NASA); NASA Ames Research Center; California State University System; San Francisco State University; Cornell University; Cornell University
  摘要：Beyond our Solar System, aurorae have been inferred from radio observations of isolated brown dwarfs(1,2). Within our Solar System, giant planets have auroral emission with signatures across the electromagnetic spectrum including infrared emission of H-3(+) and methane. Isolated brown dwarfs with auroral signatures in the radio have been searched for corresponding infrared features, but only null detections have been reported(3). CWISEP J193518.59-154620.3. (W1935 for short) is an isolated bro...
• The HEAT repeat protein HPO-27 is a lysosome fission factor AI翻译
  作者：Li, Letao; Liu, Xilu; Yang, Shanshan; Li, Meijiao; Wu, Yanwei; Hu, Siqi; Wang, Wenjuan; Jiang, Amin; Zhang, Qianqian; Zhang, Junbing; Ma, Xiaoli; Hu, Junyan; Zhao, Qiaohong; Liu, Yubing; Li, Dong; Hu, Junjie; Yang, Chonglin; Feng, Wei; Wang, Xiaochen
  作者单位：Chinese Academy of Sciences; Institute of Biophysics, CAS; Yunnan University; Yunnan University; Chinese Academy of Sciences; University of Chinese Academy of Sciences, CAS; Southern University of Science & Technology
  摘要：Lysosomes are degradation and signalling centres crucial for homeostasis, development and ageing1. To meet diverse cellular demands, lysosomes remodel their morphology and function through constant fusion and fission2,3. Little is known about the molecular basis of fission. Here we identify HPO-27, a conserved HEAT repeat protein, as a lysosome scission factor in Caenorhabditis elegans. Loss of HPO-27 impairs lysosome fission and leads to an excessive tubular network that ultimately collapses....
• Dual quantum spin Hall insulator by density-tuned correlations in TaIrTe4 AI翻译
  作者：Tang, Jian; Ding, Thomas Siyuan; Chen, Hongyu; Gao, Anyuan; Qian, Tiema; Huang, Zumeng; Sun, Zhe; Han, Xin; Strasser, Alex; Li, Jiangxu; Geiwitz, Michael; Shehabeldin, Mohamed; Belosevich, Vsevolod; Wang, Zihan; Wang, Yiping; Watanabe, Kenji; Taniguchi, Takashi; Bell, David C.; Wang, Ziqiang; Fu, Liang; Zhang, Yang; Qian, Xiaofeng; Burch, Kenneth S.; Shi, Youguo; Ni, Ni; Chang, Guoqing; Xu, Su-Yang; Ma, Qiong
  作者单位：Boston College; Nanyang Technological University; Harvard University; University of California System; University of California Los Angeles; University of California System; University of California Los Angeles; Chinese Academy of Sciences; Chinese Academy of Sciences; Institute of Physics, CAS; Texas A&M University System; Texas A&M University College Station; University of Tennessee System; University of Tennessee Knoxville; University of Tennessee System; University of Tennessee Knoxville; National Institute for Materials Science; National Institute for Materials Science; Harvard University; Harvard University; Massachusetts Institute of Technology (MIT); Canadian Institute for Advanced Research (CIFAR)
  摘要：The convergence of topology and correlations represents a highly coveted realm in the pursuit of new quantum states of matter(1). Introducing electron correlations to a quantum spin Hall (QSH) insulator can lead to the emergence of a fractional topological insulator and other exotic time-reversal-symmetric topological order(2-8), not possible in quantum Hall and Chern insulator systems. Here we report a new dual QSH insulator within the intrinsic monolayer crystal of TaIrTe4, arising from the ...
• Wildlife boost in African forests certified for sustainable logging AI翻译
  作者：Fa, Julia E.
  作者单位：Manchester Metropolitan University
  摘要：Is there a conservation benefit if tropical forests that are affected by logging gain certification from the Forest Stewardship Council? An analysis of the biodiversity outcomes in such tropical forests provides answers.
• Improving prime editing with an endogenous small RNA-binding protein AI翻译
  作者：Yan, Jun; Oyler-Castrillo, Paul; Ravisankar, Purnima; Ward, Carl C.; Levesque, Sebastien; Jing, Yangwode; Simpson, Danny; Zhao, Anqi; Li, Hui; Yan, Weihao; Goudy, Laine; Schmidt, Ralf; Solley, Sabrina C.; Gilbert, Luke A.; Chan, Michelle M.; Bauer, Daniel E.; Marson, Alexander; Parsons, Lance R.; Adamson, Britt
  作者单位：Princeton University; Princeton University; Harvard University; Harvard University Medical Affiliates; Boston Children's Hospital; Harvard University; Harvard University Medical Affiliates; Dana-Farber Cancer Institute; Harvard University; Harvard University; Massachusetts Institute of Technology (MIT); Broad Institute; Harvard University; Harvard Medical School; Princeton University; University of California System; University of California San Francisco; Medical University of Vienna; University of California System; University of California San Francisco; University of California System; University of California San Francisco; UCSF Medical Center; UCSF Helen Diller Family Comprehensive Cancer Center; University of California System; University of California Berkeley; University of California System; University of California San Francisco; Cornell University
  摘要：Prime editing enables the precise modification of genomes through reverse transcription of template sequences appended to the 3 ends of CRISPR-Cas guide RNAs1. To identify cellular determinants of prime editing, we developed scalable prime editing reporters and performed genome-scale CRISPR-interference screens. From these screens, a single factor emerged as the strongest mediator of prime editing: the small RNA-binding exonuclease protection factor La. Further investigation revealed that La p...
• Sea spray carries huge amounts of 'forever chemicals' into the air AI翻译
  作者：[Anonymous]
  摘要：Long-lived compounds emitted by industry reach the oceans and are then ferried by bubbles into the atmosphere.
• The economic commitment of climate change AI翻译
  作者：Kotz, Maximilian; Levermann, Anders; Wenz, Leonie
  作者单位：Potsdam Institut fur Klimafolgenforschung; University of Potsdam
  摘要：Global projections of macroeconomic climate-change damages typically consider impacts from average annual and national temperatures over long time horizons(1-6). Here we use recent empirical findings from more than 1,600 regions worldwide over the past 40years to project sub-national damages from temperature and precipitation, including daily variability and extremes(7,8). Using an empirical approach that provides a robust lower bound on the persistence of impacts on economic growth, we find t...