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作者:Zweibel, Ellen
作者单位:University of Wisconsin System; University of Wisconsin Madison
摘要:A phenomenon that affects the magnetic fields of rotating bodies could be involved in recurring changes in the Sun's behaviour, which are related to a periodic flipping of its field. The proposal is a fresh take on this strange effect.
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作者:Ewbank, Jonathan
摘要:Letter to the Editor
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作者:Wong, Carissa
摘要:Google scientists have modelled a fragment of the human brain at nanoscale resolution, revealing cells with previously undiscovered features.
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作者:Wienhausen, Gerrit; Moraru, Cristina; Bruns, Stefan; Tran, Den Quoc; Sultana, Sabiha; Wilkes, Heinz; Dlugosch, Leon; Azam, Farooq; Simon, Meinhard
作者单位:Carl von Ossietzky Universitat Oldenburg; University of California System; University of California San Diego; Scripps Institution of Oceanography; University of Duisburg Essen
摘要:Cobalamin (vitamin B-12, herein referred to as B-12) is an essential cofactor for most marine prokaryotes and eukaryotes(1,2). Synthesized by a limited number of prokaryotes, its scarcity affects microbial interactions and community dynamics(2-4). Here we show that two bacterial B-12 auxotrophs can salvage different B-12 building blocks and cooperate to synthesize B-12. A Colwellia sp. synthesizes and releases the activated lower ligand alpha-ribazole, which is used by another B-12 auxotroph, ...
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作者:Leeming, Jack
摘要:Neven Ivea investigates the invasive species in the Adriatic Sea, and works out how to lessen its impact.
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作者:Ewbank, Jonathan
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作者:Reglade, U.; Bocquet, A.; Gautier, R.; Cohen, J.; Marquet, A.; Albertinale, E.; Pankratova, N.; Hallen, M.; Rautschke, F.; Sellem, L. -A.; Rouchon, P.; Sarlette, A.; Mirrahimi, M.; Campagne-Ibarcq, P.; Lescanne, R.; Jezouin, S.; Leghtas, Z.
作者单位:Inria; Sorbonne Universite; Universite Paris Cite; Universite PSL; Ecole Normale Superieure (ENS); Centre National de la Recherche Scientifique (CNRS); Universite Paris Cite; Ecole Normale Superieure de Lyon (ENS de LYON); Centre National de la Recherche Scientifique (CNRS)
摘要:Quantum bits (qubits) are prone to several types of error as the result of uncontrolled interactions with their environment. Common strategies to correct these errors are based on architectures of qubits involving daunting hardware overheads(1). One possible solution is to build qubits that are inherently protected against certain types of error, so the overhead required to correct the remaining errors is greatly reduced(2-7). However, this strategy relies on one condition: any quantum manipul...
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作者:Diaz, Nuria; Perez, Carlos; Escribano, Ana Maria; Sanz, Gema; Priego, Julian; Lafuente, Celia; Barberis, Mario; Calle, Luis; Espinosa, Juan Felix; Priest, Birgit T.; Zhang, Hong Y.; Nosie, Amanda K.; Haas, Joseph V.; Cannady, Ellen; Borel, Anthony; Schultze, Albert E.; Sauder, J. Michael; Hendle, Joerg; Weichert, Ken; Nicholls, Stephen J.; Michael, Laura F.
作者单位:Eli Lilly; Lilly Research Laboratories; Eli Lilly; Lilly Research Laboratories; Eli Lilly; Lilly Research Laboratories; Monash University
摘要:Lipoprotein(a) (Lp(a)), an independent, causal cardiovascular risk factor, is a lipoprotein particle that is formed by the interaction of a low-density lipoprotein (LDL) particle and apolipoprotein(a) (apo(a))(1,2). Apo(a) first binds to lysine residues of apolipoprotein B-100 (apoB-100) on LDL through the Kringle IV (K-IV) 7 and 8 domains, before a disulfide bond forms between apo(a) and apoB-100 to create Lp(a) (refs. 3-7). Here we show that the first step of Lp(a) formation can be inhibited...
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作者:Warren, Audrey L.; Lankri, David; Cunningham, Michael J.; Serrano, Inis C.; Parise, Lyonna F.; Kruegel, Andrew C.; Duggan, Priscilla; Zilberg, Gregory; Capper, Michael J.; Havel, Vaclav; Russo, Scott J.; Sames, Dalibor; Wacker, Daniel
作者单位:Icahn School of Medicine at Mount Sinai; Columbia University; Icahn School of Medicine at Mount Sinai; Columbia University
摘要:Psychedelic substances such as lysergic acid diethylamide (LSD) and psilocybin show potential for the treatment of various neuropsychiatric disorders1-3. These compounds are thought to mediate their hallucinogenic and therapeutic effects through the serotonin (5-hydroxytryptamine (5-HT)) receptor 5-HT2A (ref. 4). However, 5-HT1A also plays a part in the behavioural effects of tryptamine hallucinogens5, particularly 5-methoxy-N,N-dimethyltryptamine (5-MeO-DMT), a psychedelic found in the toxin ...
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作者:Conroy, Gemma