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作者：Gewin, Virginia; Shirani, Shiva
作者单位：Universidad de Malaga
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作者：Kozlov, Max
摘要：Researchers have tried a bunch of strategies to get more negative results into the literature. Nature asks whether they are working.
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作者：Sykes, Rebecca Wragg
作者单位：University of Cambridge; University of Liverpool
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作者：[Anonymous]
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作者：Bosch, Miriam; Kallin, Nina; Donakonda, Sainitin; Zhang, Jitao David; Wintersteller, Hannah; Hegenbarth, Silke; Heim, Kathrin; Ramirez, Carlos; Fuerst, Anna; Lattouf, Elias Isaac; Feuerherd, Martin; Chattopadhyay, Sutirtha; Kumpesa, Nadine; Griesser, Vera; Hoflack, Jean-Christophe; Siebourg-Polster, Juliane; Mogler, Carolin; Swadling, Leo; Pallett, Laura J.; Meiser, Philippa; Manske, Katrin; de Almeida, Gustavo P.; Kosinska, Anna D.; Sandu, Ioana; Schneider, Annika; Steinbacher, Vincent; Teng, Yan; Schnabel, Julia; Theis, Fabian; Gehring, Adam J.; Boonstra, Andre; Janssen, Harry L. A.; Vandenbosch, Michiel; Cuypers, Eva; Oellinger, Rupert; Engleitner, Thomas; Rad, Roland; Steiger, Katja; Oxenius, Annette; Lo, Wan-Lin; Klepsch, Victoria; Baier, Gottfried; Holzmann, Bernhard; Maini, Mala K.; Heeren, Ron; Murray, Peter J.; Thimme, Robert; Herrmann, Carl; Protzer, Ulrike; Boettcher, Jan P.; Zehn, Dietmar; Wohlleber, Dirk; Lauer, Georg M.; Hofmann, Maike; Luangsay, Souphalone; Knolle, Percy A.
作者单位：Technical University of Munich; Roche Holding; University of Freiburg; Ruprecht Karls University Heidelberg; Harvard University; Harvard University Medical Affiliates; Massachusetts General Hospital; Harvard University; Harvard Medical School; Technical University of Munich; University of London; University College London; Technical University of Munich; Technical University of Munich; Helmholtz Association; Helmholtz-Center Munich - German Research Center for Environmental Health; German Center for Infection Research; Swiss Federal Institutes of Technology Domain; ETH Zurich; Helmholtz Association; Helmholtz-Center Munich - German Research Center for Environmental Health; Technical University of Munich; University of Toronto; University Health Network Toronto; Toronto General Hospital; University of Toronto; Erasmus University Rotterdam; Erasmus MC; University of Toronto; University Health Network Toronto; Toronto General Hospital; Maastricht University; Technical University of Munich; Technical University of Munich; Utah System of Higher Education; University of Utah; Medical University of Innsbruck; Technical University of Munich; Max Planck Society; Technical University of Munich
摘要：Chronic hepatitis B virus (HBV) infection affects 300 million patients worldwide(1,2), in whom virus-specific CD8 T cells by still ill-defined mechanisms lose their function and cannot eliminate HBV-infected hepatocytes(3-7). Here we demonstrate that a liver immune rheostat renders virus-specific CD8 T cells refractory to activation and leads to their loss of effector functions. In preclinical models of persistent infection with hepatotropic viruses such as HBV, dysfunctional virus-specific CX...
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作者：Boyle, Benjamin T.; Dow, Nathan W.; Kelly, Christopher B.; Bryan, Marian C.; MacMillan, David W. C.
作者单位：Princeton University; Johnson & Johnson; Janssen Pharmaceuticals; Johnson & Johnson; Janssen Pharmaceuticals
摘要：The ability to tame high-energy intermediates is important for synthetic chemistry, enabling the construction of complex molecules and propelling advances in the field of synthesis. Along these lines, carbenes and carbenoid intermediates are particularly attractive, but often unknown, high-energy intermediates1,2. Classical methods to access metal carbene intermediates exploit two-electron chemistry to form the carbon-metal bond. However, these methods are usually prohibitive because of reagen...
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作者：Mallapaty, Smriti
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作者：Oktaviana, Adhi Agus; Joannes-Boyau, Renaud; Hakim, Budianto; Burhan, Basran; Sardi, Ratno; Adhityatama, Shinatria; Hamrullah, Iwan; Sumantri, Iwan; Tang, M.; Lebe, Rustan; Ilyas, Imran; Abbas, Abdullah; Jusdi, Andi; Mahardian, Dewangga Eka; Noerwidi, Sofwan; Ririmasse, Marlon N. R.; Mahmud, Irfan; Duli, Akin; Aksa, Laode M.; McGahan, David; Setiawan, Pindi; Brumm, Adam; Aubert, Maxime
作者单位：Griffith University; Griffith University - Gold Coast Campus; Griffith University; Griffith University - Gold Coast Campus; Southern Cross University; Griffith University; Universitas Hasanuddin; Universitas Hasanuddin; Institute Technology of Bandung; Griffith University
摘要：Previous dating research indicated that the Indonesian island of Sulawesi is host to some of the oldest known rock art1-3. That work was based on solution uranium-series (U-series) analysis of calcite deposits overlying rock art in the limestone caves of Maros-Pangkep, South Sulawesi1-3. Here we use a novel application of this approach-laser-ablation U-series imaging-to re-date some of the earliest cave art in this karst area and to determine the age of stylistically similar motifs at other Ma...
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作者：Zhao, Peng; Xue, Wenhua; Zhang, Yue; Zhi, Shizhen; Ma, Xiaojing; Qiu, Jiamin; Zhang, Tianyu; Ye, Sheng; Mu, Huimin; Cheng, Jinxuan; Wang, Xiaodong; Hou, Shuaihang; Zhao, Lijia; Xie, Guoqiang; Cao, Feng; Liu, Xingjun; Mao, Jun; Fu, Yuhao; Wang, Yumei; Zhang, Qian
作者单位：Harbin Institute of Technology; Harbin Institute of Technology; Chinese Academy of Sciences; Institute of Physics, CAS; Jilin University; Harbin Institute of Technology; Northeastern University - China; Harbin Institute of Technology; Harbin Institute of Technology; Songshan Lake Materials Laboratory
摘要：Most of the state-of-the-art thermoelectric materials are inorganic semiconductors. Owing to the directional covalent bonding, they usually show limited plasticity at room temperature(1,2), for example, with a tensile strain of less than five per cent. Here we discover that single-crystalline Mg3Bi2 shows a room-temperature tensile strain of up to 100 per cent when the tension is applied along the (0001) plane (that is, the ab plane). Such a value is at least one order of magnitude higher than...
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作者：Chancel, Lucas
作者单位：Harvard University
