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作者:Montgomery, Beronda L.
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作者:Frankell, Alexander M.; Dietzen, Michelle; Al Bakir, Maise; Lim, Emilia L.; Karasaki, Takahiro; Ward, Sophia; Veeriah, Selvaraju; Colliver, Emma; Huebner, Ariana; Bunkum, Abigail; Hill, Mark S.; Grigoriadis, Kristiana; Moore, David A.; Black, James R. M.; Liu, Wing Kin; Thol, Kerstin; Pich, Oriol; Watkins, Thomas B. K.; Naceur-Lombardelli, Cristina; Cook, Daniel E.; Salgado, Roberto; Wilson, Gareth A.; Bailey, Chris; Angelova, Mihaela; Bentham, Robert; Martinez-Ruiz, Carlos; Abbosh, Christopher; Nicholson, Andrew G.; Le Quesne, John; Biswas, Dhruva; Rosenthal, Rachel; Puttick, Clare; Hessey, Sonya; Lee, Claudia; Prymas, Paulina; Toncheva, Antonia; Smith, Jon; Xing, Wei; Nicod, Jerome; Price, Gillian; Kerr, Keith M.; Naidu, Babu; Middleton, Gary; Blyth, Kevin G.; Fennell, Dean A.; Forster, Martin D.; Lee, Siow Ming; Falzon, Mary; Hewish, Madeleine; Shackcloth, Michael J.; Lim, Eric; Benafif, Sarah; Russell, Peter; Boleti, Ekaterini; Krebs, Matthew G.; Lester, Jason F.; Papadatos-Pastos, Dionysis; Ahmad, Tanya; Thakrar, Ricky M.; Lawrence, David; Navani, Neal; Janes, Sam M.; Dive, Caroline; Blackhall, Fiona H.; Summers, Yvonne; Cave, Judith; Marafioti, Teresa; Herrero, Javier; Quezada, Sergio A.; Peggs, Karl S.; Schwarz, Roland F.; Van Loo, Peter; Miedema, Daniel M.; Birkbak, Nicolai J.; Hiley, Crispin T.; Hackshaw, Allan; Zaccaria, Simone; Jamal-Hanjani, Mariam; McGranahan, Nicholas; Swanton, Charles
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作者:Koltai, Julia; Kecskes, Gabor; Wilhelm, Imola; Lengyel, Balazs
作者单位:HUN-REN; HUN-REN Centre for Social Sciences; HUN-REN; HUN-REN Biological Research Center
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作者:Mijumbi, Rhona
作者单位:Liverpool School of Tropical Medicine
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作者:Vestin, Patrik
作者单位:Lund University
摘要:Field studies reveal that the woody surfaces of upland trees are a substantial global sink for methane, a potent greenhouse gas. The findings help to fill a hole in the global methane budget and should improve the accuracy of climate models.
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作者:[Anonymous]
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作者:Lu, Jun; Wu, Wenbing; Colombari, Felippe Mariano; Jawaid, Ali; Seymour, Bryan; Whisnant, Kody; Zhong, Xiaoyang; Choi, Wonjin; Chalmpes, Nikolaos; Lahann, Joerg; Vaia, Richard A.; de Moura, Andre Farias; Nepal, Dhriti; Kotov, Nicholas A.
作者单位:Cornell University
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作者:Park, Juhyung; Wu, Jibo; Szkop, Krzysztof J.; Jeong, Jinho; Jovanovic, Predrag; Husmann, Dylan; Flores, Natasha M.; Francis, Joel W.; Chen, Ying-Jiun C.; Benitez, Ana Morales; Zahn, Emily; Song, Shumei; Ajani, Jaffer A.; Wang, Linghua; Singh, Kamini; Larsson, Ola; Garcia, Benjamin A.; Topisirovic, Ivan; Gozani, Or; Mazur, Pawel K.
作者单位:Stanford University; University of Texas System; UTMD Anderson Cancer Center; Karolinska Institutet; Lady Davis Institute; McGill University; McGill University; Washington University (WUSTL); University of Texas System; UTMD Anderson Cancer Center; University of Texas System; UTMD Anderson Cancer Center; Montefiore Medical Center; Albert Einstein College of Medicine; Yeshiva University; University of Texas System; UTMD Anderson Cancer Center
摘要:Dysregulated transcription due to disruption in histone lysine methylation dynamics is an established contributor to tumorigenesis(1,2). However, whether analogous pathologic epigenetic mechanisms act directly on the ribosome to advance oncogenesis is unclear. Here we find that trimethylation of the core ribosomal protein L40 (rpL40) at lysine 22 (rpL40K22me3) by the lysine methyltransferase SMYD5 regulates mRNA translation output to promote malignant progression of gastric adenocarcinoma (GAC...
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作者:Liu, Peng; Panda, Kaushik; Edwards, Seth A.; Swanson, Ryan; Yi, Hochul; Pandesha, Pratheek; Hung, Yu-Hung; Klaas, Gerald; Ye, Xudong; Collins, Megan V.; Renken, Kaili N.; Gilbertson, Larry A.; Veena, Veena; Hancock, C. Nathan; Slotkin, R. Keith
作者单位:Donald Danforth Plant Science Center; University of Missouri System; University of Missouri Columbia; Donald Danforth Plant Science Center; Washington University (WUSTL); Bayer AG; Bayer CropScience
摘要:The current technologies to place new DNA into specific locations in plant genomes are low frequency and error-prone, and this inefficiency hampers genome-editing approaches to develop improved crops1,2. Often considered to be genome 'parasites', transposable elements (TEs) evolved to insert their DNA seamlessly into genomes3-5. Eukaryotic TEs select their site of insertion based on preferences for chromatin contexts, which differ for each TE type6-9. Here we developed a genome engineering too...
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作者:Zhu, Yinghao; Peng, Di; Zhang, Enkang; Pan, Bingying; Chen, Xu; Chen, Lixing; Ren, Huifen; Liu, Feiyang; Hao, Yiqing; Li, Nana; Xing, Zhenfang; Lan, Fujun; Han, Jiyuan; Wang, Junjie; Jia, Donghan; Wo, Hongliang; Gu, Yiqing; Gu, Yimeng; Ji, Li; Wang, Wenbin; Gou, Huiyang; Shen, Yao; Ying, Tianping; Chen, Xiaolong; Yang, Wenge; Cao, Huibo; Zheng, Changlin; Zeng, Qiaoshi; Guo, Jian-gang; Zhao, Jun
作者单位:Fudan University; Fudan University; Ocean University of China; Chinese Academy of Sciences; Institute of Physics, CAS; United States Department of Energy (DOE); Oak Ridge National Laboratory; Chinese Academy of Sciences; University of Chinese Academy of Sciences, CAS; Fudan University; Fudan University
摘要:The pursuit of discovering new high-temperature superconductors that diverge from the copper-based model(1-3) has profound implications for explaining mechanisms behind superconductivity and may also enable new applications(4-8). Here our investigation shows that the application of pressure effectively suppresses the spin-charge order in trilayer nickelate La4Ni3O10-delta single crystals, leading to the emergence of superconductivity with a maximum critical temperature (T-c) of around 30 K at ...