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作者：Shumailov, Ilia; Shumaylov, Zakhar; Zhao, Yiren; Papernot, Nicolas; Anderson, Ross; Gal, Yarin
作者单位：University of Oxford; University of Cambridge; Imperial College London; University of Toronto; Vector Institute for Artificial Intelligence; University of Cambridge; University of Edinburgh
摘要：Stable diffusion revolutionized image creation from descriptive text. GPT-2 (ref. 1), GPT-3(.5) (ref. 2) and GPT-4 (ref. 3) demonstrated high performance across a variety of language tasks. ChatGPT introduced such language models to the public. It is now clear that generative artificial intelligence (AI) such as large language models (LLMs) is here to stay and will substantially change the ecosystem of online text and images. Here we consider what may happen to GPT-{n} once LLMs contribute muc...
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作者：Zampaloni, Claudia; Mattei, Patrizio; Bleicher, Konrad; Winther, Lotte; Thate, Claudia; Bucher, Christian; Adam, Jean-Michel; Alanine, Alexander; Amrein, Kurt E.; Baidin, Vadim; Bieniossek, Christoph; Bissantz, Caterina; Boess, Franziska; Cantrill, Carina; Clairfeuille, Thomas; Dey, Fabian; Di Giorgio, Patrick; du Castel, Pauline; Dylus, David; Dzygiel, Pawel; Felici, Antonio; Garcia-Alcalde, Fernando; Haldimann, Andreas; Leipner, Matthew; Leyn, Semen; Louvel, Severine; Misson, Pauline; Osterman, Andrei; Pahil, Karanbir; Rigo, Sebastien; Schaublin, Adrian; Scharf, Sebastian; Schmitz, Petra; Stoll, Theodor; Trauner, Andrej; Zoffmann, Sannah; Kahne, Daniel; Young, John A. T.; Lobritz, Michael A.; Bradley, Kenneth A.
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作者：Wenger, Emily
作者单位：Duke University
摘要：Generative AI models are now widely accessible, enabling everyone to create their own machine-made something. But these models can collapse if their training data sets contain too much AI-generated content.
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作者：Xiao, Jianzhuang; Zou, Shuai
作者单位：Tongji University; Hong Kong Polytechnic University
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作者：Duttke, Sascha H.; Guzman, Carlos; Chang, Max; Delos Santos, Nathaniel P.; McDonald, Bayley R.; Xie, Jialei; Carlin, Aaron F.; Heinz, Sven; Benner, Christopher
作者单位：Washington State University; University of California System; University of California San Diego; University of California System; University of California San Diego
摘要：Patterns of transcriptional activity are encoded in our genome through regulatory elements such as promoters or enhancers that, paradoxically, contain similar assortments of sequence-specific transcription factor (TF) binding sites(1-3). Knowledge of how these sequence motifs encode multiple, often overlapping, gene expression programs is central to understanding gene regulation and how mutations in non-coding DNA manifest in disease(4,5). Here, by studying gene regulation from the perspective...
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作者：Ro, Christine
摘要：Nature sent a reporter to find out as part of an investigation into dud events.
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作者：Bernaschi, Massimo; Gonzalez-Adalid Pemartin, Isidoro; Martin-Mayor, Victor; Parisi, Giorgio
作者单位：Consiglio Nazionale delle Ricerche (CNR); Consejo Superior de Investigaciones Cientificas (CSIC); CSIC - UAM - Institut de Fisica Teorica (IFT); Complutense University of Madrid; Sapienza University Rome; Consiglio Nazionale delle Ricerche (CNR)
摘要：Quantum annealers are commercial devices that aim to solve very hard computational problems(1), typically those involving spin glasses(2,3). Just as in metallurgic annealing, in which a ferrous metal is slowly cooled(4), quantum annealers seek good solutions by slowly removing the transverse magnetic field at the lowest possible temperature. Removing the field diminishes the quantum fluctuations but forces the system to traverse the critical point that separates the disordered phase (at large ...
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作者：Nowogrodzki, Julian
摘要：Companies are using artificial intelligence tools to help scientists to query their data without the need for programming skills.
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作者：Hoer, Jens; Wolf, Sharon G.; Sorek, Rotem
作者单位：Weizmann Institute of Science; Weizmann Institute of Science; Helmholtz Association; Helmholtz-Center for Infection Research
摘要：Several immune pathways in humans conjugate ubiquitin-like proteins to virus and host molecules as a means of antiviral defence(1-5). Here we studied an antiphage defence system in bacteria, comprising a ubiquitin-like protein, ubiquitin-conjugating enzymes E1 and E2, and a deubiquitinase. We show that during phage infection, this system specifically conjugates the ubiquitin-like protein to the phage central tail fibre, a protein at the tip of the tail that is essential for tail assembly as we...
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作者：Ledford, Heidi
