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作者:Callaway, Ewen
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作者:Fleming, Nic
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作者:Lindhout, Feline W.; Krienen, Fenna M.; Pollard, Katherine S.; Lancaster, Madeline A.
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作者:Vesper, Inga
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作者:Wang, Ningning; Wang, Gang; Shen, Xiaoling; Hou, Jun; Luo, Jun; Ma, Xiaoping; Yang, Huaixin; Shi, Lifen; Dou, Jie; Feng, Jie; Yang, Jie; Shi, Yunqing; Ren, Zhian; Ma, Hanming; Yang, Pengtao; Liu, Ziyi; Liu, Yue; Zhang, Hua; Dong, Xiaoli; Wang, Yuxin; Jiang, Kun; Hu, Jiangping; Nagasaki, Shoko; Kitagawa, Kentaro; Calder, Stuart; Yan, Jiaqiang; Sun, Jianping; Wang, Bosen; Zhou, Rui; Uwatoko, Yoshiya; Cheng, Jinguang
作者单位:Chinese Academy of Sciences; Chinese Academy of Sciences; Institute of Physics, CAS; Chinese Academy of Sciences; University of Chinese Academy of Sciences, CAS; University of Tokyo; Shanghai Jiao Tong University; United States Department of Energy (DOE); Oak Ridge National Laboratory; United States Department of Energy (DOE); Oak Ridge National Laboratory
摘要:The Ruddlesden-Popper (R-P) bilayer nickelate, La3Ni2O7, was recently found to show signatures of high-temperature superconductivity (HTSC) at pressures above 14 GPa (ref. 1). Subsequent investigations achieved zero resistance in single-crystalline and polycrystalline samples under hydrostatic pressure conditions(2-4). Yet, obvious diamagnetic signals, the other hallmark of superconductors, are still lacking owing to the filamentary nature with low superconducting volume fraction(2,4,5). The p...
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作者:Al Zubaydi, Samir; Waske, Shivam; Akyildiz, Volkan; Starbuck, Hunter F.; Majumder, Mayukh; Moore, Curtis E.; Kalyani, Dipannita; Sevov, Christo S.
作者单位:University System of Ohio; Ohio State University; Ataturk University; Merck & Company; Merck & Company USA
摘要:The selective cross-coupling of two alkyl electrophiles to construct complex molecules remains a challenge in organic synthesis1,2. Known reactions are optimized for specific electrophiles and are not amenable to interchangeably varying electrophilic substrates that are sourced from common alkyl building blocks, such as amines, carboxylic acids and halides3-5. These limitations restrict the types of alkyl substrate that can be modified and, ultimately, the chemical space that can be explored6....
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作者:Diana, Zoie T.; Rochman, Chelsea M.; Mallos, Nicholas
作者单位:University of Toronto
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作者:Pannone, Andrew; Raj, Aditya; Ravichandran, Harikrishnan; Das, Sarbashis; Chen, Ziheng; Price, Collin A.; Sultana, Mahmooda; Das, Saptarshi
作者单位:Pennsylvania Commonwealth System of Higher Education (PCSHE); Pennsylvania State University; Pennsylvania State University - University Park; Pennsylvania Commonwealth System of Higher Education (PCSHE); Pennsylvania State University; Pennsylvania State University - University Park; National Aeronautics & Space Administration (NASA); NASA Goddard Space Flight Center; Pennsylvania Commonwealth System of Higher Education (PCSHE); Pennsylvania State University; Pennsylvania State University - University Park
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作者:Hadas, Ron; Rubinstein, Hernan; Mittnenzweig, Markus; Mayshar, Yoav; Ben-Yair, Raz; Cheng, Saifeng; Aguilera-Castrejon, Alejandro; Reines, Netta; Orenbuch, Ayelet-Hashahar; Lifshitz, Aviezer; Chen, Dong-Yuan; Elowitz, Michael B.; Zernicka-Goetz, Magdalena; Hanna, Jacob H.; Tanay, Amos; Stelzer, Yonatan
作者单位:Weizmann Institute of Science; Weizmann Institute of Science; Weizmann Institute of Science; California Institute of Technology; University of Cambridge
摘要:The developing placenta, which in mice originates through the extraembryonic ectoderm (ExE), is essential for mammalian embryonic development. Yet unbiased characterization of the differentiation dynamics of the ExE and its interactions with the embryo proper remains incomplete. Here we develop a temporal single-cell model of mouse gastrulation that maps continuous and parallel differentiation in embryonic and extraembryonic lineages. This is matched with a three-way perturbation approach to t...
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作者:Katz, Mark A.; Sawyer, Edith M.; Oriolt, Luke; Kozlova, Albina; Williams, Madison C.; Margolis, Shally R.; Johnson, Matthew; Bondy-Denomy, Joseph; Meeske, Alexander J.
作者单位:University of Washington; University of Washington Seattle; University of California System; University of California San Francisco
摘要:Prokaryotic CRISPR-Cas immunity is subverted by anti-CRISPRs (Acrs), which inhibit Cas protein activities when expressed during the phage lytic cycle or from resident prophages or plasmids1. Acrs often bind to specific cognate Cas proteins, and hence inhibition is typically limited to a single CRISPR-Cas subtype2. Furthermore, although acr genes are frequently organized together in phage-associated gene clusters3, how such inhibitors initially evolve has remained unclear. Here we investigated ...