Nature

最新文章

• Sewage lurks in coastal waters - often unnoticed by widely used test AI翻译
  作者：[Anonymous]
  摘要：Global survey finds human faecal contamination in at least one sample from all 18 cities tested.
• World-first therapy using donor cells sends autoimmune diseases into remission AI翻译
  作者：Mallapaty, Smriti
• Dietary restriction impacts health and lifespan of genetically diverse mice AI翻译
  作者：Di Francesco, Andrea; Deighan, Andrew G.; Litichevskiy, Lev; Chen, Zhenghao; Luciano, Alison; Robinson, Laura; Garland, Gaven; Donato, Hannah; Vincent, Matthew; Schott, Will; Wright, Kevin M.; Raj, Anil; Prateek, G. V.; Mullis, Martin; Hill, Warren G.; Zeidel, Mark L.; Peters, Luanne L.; Harding, Fiona; Botstein, David; Korstanje, Ron; Thaiss, Christoph A.; Freund, Adam; Churchill, Gary A.
  作者单位：Jackson Laboratory; University of Pennsylvania; University of Pennsylvania; Harvard University; Harvard University Medical Affiliates; Beth Israel Deaconess Medical Center; Harvard University; Harvard Medical School
  摘要：Caloric restriction extends healthy lifespan in multiple species(1). Intermittent fasting, an alternative form of dietary restriction, is potentially more sustainable in humans, but its effectiveness remains largely unexplored(2-8). Identifying the most efficacious forms of dietary restriction is key for developing interventions to improve human health and longevity(9). Here we performed an extensive assessment of graded levels of caloric restriction (20% and 40%) and intermittent fasting (1 a...
• Single-neuron representations of odours in the human brain AI翻译
  作者：Kehl, Marcel S.; Mackay, Sina; Ohla, Kathrin; Schneider, Matthias; Borger, Valeri; Surges, Rainer; Spehr, Marc; Mormann, Florian
  作者单位：University of Bonn; University of Oxford; University of Bonn; RWTH Aachen University
  摘要：Olfaction is a fundamental sensory modality that guides animal and human behaviour(1,2). However, the underlying neural processes of human olfaction are still poorly understood at the fundamental-that is, the single-neuron-level. Here we report recordings of single-neuron activity in the piriform cortex and medial temporal lobe in awake humans performing an odour rating and identification task. We identified odour-modulated neurons within the piriform cortex, amygdala, entorhinal cortex and hi...
• Planning for life on Mars AI翻译
  作者：Bhambra, Raveena
• Lethal Marburg virus is on the rise in Rwanda: why scientists are worried AI翻译
  作者：Sidik, Saima
  摘要：There is no proven vaccine or treatment for infections with the virus, which is closely related to Ebola virus and causes similar symptoms.
• Conservationists must address how war affects species and ecosystems AI翻译
  作者：Weir, Doug; Durant, Sarah M.; Schulte To Buehne, Henrike; Hoffmann, Michael; Petrovych, Olesya; Sua Carvajal, Beth; Fernandes Elizalde, Sara
  作者单位：University of London; King's College London; Zoological Society of London; Zoological Society of London
• Structure of a fully assembled γδ T cell antigen receptor AI翻译
  作者：Gully, Benjamin S.; Fernandes, Joao Ferreira; Gunasinghe, Sachith D.; Vuong, Mai T.; Lui, Yuan; Rice, Michael T.; Rashleigh, Liam; Lay, Chan-sien; Littler, Dene R.; Sharma, Sumana; Santos, Ana Mafalda; Venugopal, Hariprasad; Rossjohn, Jamie; Davis, Simon J.
  作者单位：Monash University; Monash University; University of Oxford; University of Oxford; Cardiff University
  摘要：T cells in jawed vertebrates comprise two lineages, alpha beta T cells and gamma delta T cells, defined by the antigen receptors they express-that is, alpha beta and gamma delta T cell receptors (TCRs), respectively. The two lineages have different immunological roles, requiring that gamma delta TCRs recognize more structurally diverse ligands1. Nevertheless, the receptors use shared CD3 subunits to initiate signalling. Whereas the structural organization of alpha beta TCRs is understood2,3, t...
• Spillover of highly pathogenic avian influenza H5N1 virus to dairy cattle AI翻译
  作者：Caserta, Leonardo C.; Frye, Elisha A.; Butt, Salman L.; Laverack, Melissa; Nooruzzaman, Mohammed; Covaleda, Lina M.; Thompson, Alexis C.; Koscielny, Melanie Prarat; Cronk, Brittany; Johnson, Ashley; Kleinhenz, Katie; Edwards, Erin E.; Gomez, Gabriel; Hitchener, Gavin; Martins, Mathias; Kapczynski, Darrell R.; Suarez, David L.; Morris, Ellen Ruth Alexander; Hensley, Terry; Beeby, John S.; Lejeune, Manigandan; Swinford, Amy K.; Elvinger, Francois; Dimitrov, Kiril M.; Diel, Diego G.
  作者单位：Cornell University; Texas A&M University System; Texas A&M University College Station; United States Department of Agriculture (USDA)
  摘要：The highly pathogenic avian influenza (HPAI) H5N1 virus clade 2.3.4.4b has caused the death of millions of domestic birds and thousands of wild birds in the USA since January 2022 (refs. 1-4). Throughout this outbreak, spillovers to mammals have been frequently documented5-12. Here we report spillover of the HPAI H5N1 virus to dairy cattle across several states in the USA. The affected cows displayed clinical signs encompassing decreased feed intake, altered faecal consistency, respiratory dis...
• Rwanda: seven swift steps for managing Marburg virus AI翻译
  作者：Rwagasore, Edson; Muvunyi, Claude Mambo; Butera, Yvan; Nsanzimana, Sabin; Condo, Jeanine
  作者单位：Rwanda Biomedical Center