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作者：Warbinek, Jessica; Rickert, Elisabeth; Raeder, Sebastian; Albrecht-Schonzart, Thomas; Andelic, Brankica; Auler, Julian; Bally, Benjamin; Bender, Michael; Berndt, Sebastian; Block, Michael; Brizard, Alexandre; Chauveau, Pierre; Cheal, Bradley; Chhetri, Premaditya; Claessens, Arno; de Roubin, Antoine; Devlin, Charlie; Dorrer, Holger; Duellmann, Christoph E.; Ezold, Julie; Ferrer, Rafael; Gadelshin, Vadim; Gaiser, Alyssa; Giacoppo, Francesca; Goriely, Stephane; Gutierrez, Manuel J.; Harvey, Ashley; Hasse, Raphael; Heinke, Reinhard; Hessberger, Fritz-Peter; Hilaire, Stephane; Kaja, Magdalena; Kaleja, Oliver; Kieck, Tom; Kim, Eunkang; Kneip, Nina; Koester, Ulli; Kraemer, Sandro; Laatiaoui, Mustapha; Lantis, Jeremy; Lecesne, Nathalie; Loria Basto, Andrea Tzeitel; Mistry, Andrew Kishor; Mokry, Christoph; Moore, Iain; Murboeck, Tobias; Muenzberg, Danny; Nazarewicz, Witold; Niemeyer, Thorben; Nothhelfer, Steven; Peru, Sophie; Raggio, Andrea; Reinhard, Paul-Gerhard; Renisch, Dennis; Rey-Herme, Emmanuel; Romans, Jekabs; Romero Romero, Elisa; Runke, Joerg; Ryssens, Wouter; Savajols, Herve; Schneider, Fabian; Sperling, Joseph; Stemmler, Matou; Studer, Dominik; Thoerle-Pospiech, Petra; Trautmann, Norbert; Urquiza-Gonzalez, Mitzi; van Beek, Kenneth; Van Cleve, Shelley; Van Duppen, Piet; Vandebrouck, Marine; Verstraelen, Elise; Walther, Thomas; Weber, Felix; Wendt, Klaus
作者单位：Helmholtz Association; GSI Helmholtz-Center for Heavy Ion Research; Johannes Gutenberg University of Mainz; Colorado School of Mines; University of Groningen; Universite Paris Saclay; CEA; Centre National de la Recherche Scientifique (CNRS); CNRS - National Institute of Nuclear and Particle Physics (IN2P3); Universite Claude Bernard Lyon 1; CEA; University of Liverpool; KU Leuven; United States Department of Energy (DOE); Oak Ridge National Laboratory; Johannes Gutenberg University of Mainz; Michigan State University; Michigan State University; Universite Libre de Bruxelles; CEA; Universite Paris Saclay; CEA; Universitat Greifswald; Institut Laue-Langevin (ILL); Helmholtz Association; GSI Helmholtz-Center for Heavy Ion Research; Technical University of Darmstadt; University of Jyvaskyla; Michigan State University; University of Erlangen Nuremberg; CEA; Universite Paris Saclay; University of Gothenburg; European Organization for Nuclear Research (CERN)
摘要：The quantum-mechanical nuclear-shell structure determines the stability and limits of the existence of the heaviest nuclides with large proton numbers Z greater than or similar to 100 (refs. 1-3). Shell effects also affect the sizes and shapes of atomic nuclei, as shown by laser spectroscopy studies in lighter nuclides4. However, experimental information on the charge radii and the nuclear moments of the heavy actinide elements, which link the heaviest naturally abundant nuclides with artifici...
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作者：Gattinoni, Chiara
作者单位：University of London; King's College London
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作者：Bai, Xiuhui; Hu, Pengfei; Li, Ang; Zhang, Youwei; Li, Aowen; Zhang, Guangjie; Xue, Yufeng; Jiang, Tianxing; Wang, Zezhou; Cui, Hanke; Kang, Jianxin; Zhao, Hewei; Gu, Lin; Zhou, Wu; Liu, Li-Min; Qiu, Xiaohui; Guo, Lin
作者单位：Beihang University; Chinese Academy of Sciences; University of Chinese Academy of Sciences, CAS; Chinese Academy of Sciences; National Center for Nanoscience & Technology, CAS; Beihang University; Tsinghua University; Tsinghua University; Chinese Academy of Sciences; University of Chinese Academy of Sciences, CAS
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作者：Ruetz, Tyson J.; Pogson, Angela N.; Kashiwagi, Chloe M.; Gagnon, Stephanie D.; Morton, Bhek; Sun, Eric D.; Na, Jeeyoon; Yeo, Robin W.; Leeman, Dena S.; Morgens, David W.; Tsui, C. Kimberly; Li, Amy; Bassik, Michael C.; Brunet, Anne
作者单位：Stanford University; Stanford University; Stanford University; Stanford University; Stanford University; Stanford University
摘要：Ageing impairs the ability of neural stem cells (NSCs) to transition from quiescence to proliferation in the adult mammalian brain. Functional decline of NSCs results in the decreased production of new neurons and defective regeneration following injury during ageing(1-4). Several genetic interventions have been found to ameliorate old brain function(5-8), but systematic functional testing of genes in old NSCs-and more generally in old cells-has not been done. Here we develop in vitro and in v...
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作者：Gazzard, Abigail; Macdonald, David W.; Lund Rasmussen, Sophie
作者单位：University of Oxford
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作者：Islam, Mirazul; Yang, Yilin; Simmons, Alan J.; Shah, Vishal M.; Musale, Krushna Pavan; Xu, Yanwen; Tasneem, Naila; Chen, Zhengyi; Trinh, Linh T.; Molina, Paola; Ramirez-Solano, Marisol A.; Sadien, Iannish D.; Dou, Jinzhuang; Rolong, Andrea; Chen, Ken; Magnuson, Mark A.; Rathmell, Jeffrey C.; Macara, Ian G.; Winton, Douglas J.; Liu, Qi; Zafar, Hamim; Kalhor, Reza; Church, George M.; Shrubsole, Martha J.; Coffey, Robert J.; Lau, Ken S.
作者单位：Vanderbilt University; Vanderbilt University; Indian Institute of Technology System (IIT System); Indian Institute of Technology (IIT) - Kanpur; Vanderbilt University; Vanderbilt University; Vanderbilt University; Vanderbilt University; University of Cambridge; CRUK Cambridge Institute; Cancer Research UK; University of Texas System; UTMD Anderson Cancer Center; Vanderbilt University; Vanderbilt University; Vanderbilt University; Indian Institute of Technology System (IIT System); Indian Institute of Technology (IIT) - Kanpur; Johns Hopkins University; Harvard University; Harvard Medical School; Harvard University; Vanderbilt University; Vanderbilt University; Vanderbilt University; Vanderbilt University
摘要：Temporal ordering of cellular events offers fundamental insights into biological phenomena. Although this is traditionally achieved through continuous direct observations1,2, an alternative solution leverages irreversible genetic changes, such as naturally occurring mutations, to create indelible marks that enables retrospective temporal ordering3-5. Using a multipurpose, single-cell CRISPR platform, we developed a molecular clock approach to record the timing of cellular events and clonality ...
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作者：Ledford, Heidi
摘要：'Bricks' of DNA, some of which have chemical tags, could one day be an alternative to storing information electronically.
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作者：Naddaf, Miryam
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作者：Nozaki, Tadasu; Weiner, Beth; Kleckner, Nancy
作者单位：Harvard University
摘要：A central feature of meiosis is the pairing of homologous maternal and paternal chromosomes ('homologues') along their lengths(1-3). Recognition between homologues and their juxtaposition in space is mediated by axis-associated recombination complexes. Also, pairing must occur without entanglements among unrelated chromosomes. Here we examine homologue juxtaposition in real time by four-dimensional fluorescence imaging of tagged chromosomal loci at high spatio-temporal resolution in budding ye...
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作者：[Anonymous]
