Nature

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• Robotic exoskeleton adapts to changes in leg movements in real time AI翻译
  作者：Kim, Myunghee; Major, Matthew J.
  作者单位：University of Illinois System; University of Illinois Chicago; University of Illinois Chicago Hospital; Northwestern University; Feinberg School of Medicine; US Department of Veterans Affairs; Veterans Health Administration (VHA); Jesse Brown VA Medical Center; US Department of Veterans Affairs; Veterans Health Administration (VHA); Jesse Brown VA Medical Center
  摘要：Wearable robots that assist leg movements could transform the lives of people with reduced mobility - but only if the devices can adapt in real time to support a vast range of human activities. Machine learning provides a way forward.
• The quest to build bionic limbs that feel like the real thing AI翻译
  作者：Schwaller, Fred
• Ignoring journal metrics on CVs is an act of privilege AI翻译
  作者：Souza-Neto, Valerio
  作者单位：Griffith University
• No hearing aids needed: bats' ears stay keen well into old age AI翻译
  作者：[Anonymous]
• Temporally distinct 3D multi-omic dynamics in the developing human brain AI翻译
  作者：Heffel, Matthew G.; Zhou, Jingtian; Zhang, Yi; Lee, Dong-Sung; Hou, Kangcheng; Pastor-Alonso, Oier; Abuhanna, Kevin D.; Galasso, Joseph; Kern, Colin; Tai, Chu-Yi; Garcia-Padilla, Carlos; Nafisi, Mahsa; Zhou, Yi; Schmitt, Anthony D.; Li, Terence; Haeussler, Maximilian; Wick, Brittney; Zhang, Martin Jinye; Xie, Fangming; Ziffra, Ryan S.; Mukamel, Eran A.; Eskin, Eleazar; Nowakowski, Tomasz J.; Dixon, Jesse R.; Pasaniuc, Bogdan; Ecker, Joseph R.; Zhu, Quan; Bintu, Bogdan; Paredes, Mercedes F.; Luo, Chongyuan
  作者单位：University of California System; University of California Los Angeles; University of California System; University of California Los Angeles; Salk Institute; University of California System; University of California San Diego; Seoul National University (SNU); Seoul National University (SNU); University of California System; University of California Los Angeles; University of California Los Angeles Medical Center; David Geffen School of Medicine at UCLA; University of California System; University of California Los Angeles; University of California Los Angeles Medical Center; David Geffen School of Medicine at UCLA; University of California System; University of California San Francisco; University of California System; University of California Los Angeles; University of California Los Angeles Medical Center; David Geffen School of Medicine at UCLA; University of California System; University of California San Diego; University of California System; University of California San Diego; University of California System; University of California Santa Cruz; Carnegie Mellon University; Harvard University; Harvard T.H. Chan School of Public Health; University of California System; University of California San Diego; University of California System; University of California San Francisco; University of California System; University of California San Francisco; University of California System; University of California San Francisco; University of California System; University of California San Francisco; University of California System; University of California Los Angeles; Salk Institute; Howard Hughes Medical Institute; Salk Institute; University of California System; University of California San Francisco; University of California System; University of California San Francisco; University of California System; University of California San Francisco
  摘要：The human hippocampus and prefrontal cortex play critical roles in learning and cognition1,2, yet the dynamic molecular characteristics of their development remain enigmatic. Here we investigated the epigenomic and three-dimensional chromatin conformational reorganization during the development of the hippocampus and prefrontal cortex, using more than 53,000 joint single-nucleus profiles of chromatin conformation and DNA methylation generated by single-nucleus methyl-3C sequencing (snm3C-seq3)...
• Scientists must hold President Trump to account with courage and unity AI翻译
  作者：[Anonymous]
• Dopamine dynamics are dispensable for movement but promote reward responses AI翻译
  作者：Cai, Xintong; Liu, Changliang; Tsutsui-Kimura, Iku; Lee, Joon-Hyuk; Guo, Chong; Banerjee, Aditi; Lee, Jinoh; Amo, Ryunosuke; Xie, Yudi; Patriarchi, Tommaso; Li, Yulong; Watabe-Uchida, Mitsuko; Uchida, Naoshige; Kaeser, Pascal S.
  作者单位：Harvard University; Harvard Medical School; Harvard University; University of Zurich; Swiss Federal Institutes of Technology Domain; ETH Zurich; University of Zurich; Peking University
  摘要：Dopamine signalling modes differ in kinetics and spatial patterns of receptor activation1,2. How these modes contribute to motor function, motivation and learning has long been debated3-21. Here we show that action-potential-induced dopamine release is dispensable for movement initiation but supports reward-oriented behaviour. We generated mice with dopamine-neuron-specific knockout of the release site organizer protein RIM to disrupt action-potential-induced dopamine release. In these mice, r...
• CIRCULAR LOGIC: UNPICKING RNA'S STRANGEST FORM YET AI翻译
  作者：Dance, Amber
• Systemic biases are leading to an intersex research void AI翻译
  作者：Stokes, Alexander J.; Vary, Nick G.; Lorshbough, Erika L.
  作者单位：University of Hawaii System
• Selective ion transport through hydrated micropores in polymer membranes AI翻译
  作者：Wang, Anqi; Breakwell, Charlotte; Foglia, Fabrizia; Tan, Rui; Lovell, Louie; Wei, Xiaochu; Wong, Toby; Meng, Naiqi; Li, Haodong; Seel, Andrew; Sarter, Mona; Smith, Keenan; Alvarez-Fernandez, Alberto; Furedi, Mate; Guldin, Stefan; Britton, Melanie M.; McKeown, Neil B.; Jelfs, Kim E.; Song, Qilei
  作者单位：Imperial College London; Imperial College London; University of London; University College London; University of Birmingham; UK Research & Innovation (UKRI); Science & Technology Facilities Council (STFC); STFC Rutherford Appleton Laboratory; University of London; Royal Holloway University London; University of London; University College London; University of Edinburgh; King Abdullah University of Science & Technology
  摘要：Ion-conducting polymer membranes are essential in many separation processes and electrochemical devices, including electrodialysis1, redox flow batteries2, fuel cells3 and electrolysers4,5. Controlling ion transport and selectivity in these membranes largely hinges on the manipulation of pore size. Although membrane pore structures can be designed in the dry state6, they are redefined upon hydration owing to swelling in electrolyte solutions. Strategies to control pore hydration and a deeper u...