Nature

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• Martian rock hints at ancient dense atmosphere AI翻译
  作者：[Anonymous]
• The do's and don'ts of scientific image editing AI翻译
  作者：Reardon, Sara
• Eugenics is on the rise again: human geneticists must take a stand AI翻译
  作者：Wojcik, Genevieve L.
  作者单位：Johns Hopkins University; Johns Hopkins Bloomberg School of Public Health
• The distribution of subsurface microplastics in the ocean AI翻译
  作者：Zhao, Shiye; Kvale, Karin F.; Zhu, Lixin; Zettler, Erik R.; Egger, Matthias; Mincer, Tracy J.; Amaral-Zettler, Linda A.; Lebreton, Laurent; Niemann, Helge; Nakajima, Ryota; Thiel, Martin; Bos, Ryan P.; Galgani, Luisa; Stubbins, Aron
  作者单位：Japan Agency for Marine-Earth Science & Technology (JAMSTEC); East China Normal University; Northeastern University; Utrecht University; Royal Netherlands Institute for Sea Research (NIOZ); State University System of Florida; Florida Atlantic University; University of Amsterdam; Utrecht University; Universidad Catolica del Norte; Smithsonian Institution; Smithsonian Environmental Research Center; Harvard University; University of Siena; National Biodiversity Future Center; Northeastern University; Northeastern University
  摘要：Marine plastic pollution is a global issue, with microplastics (1 mu m-5 mm) dominating the measured plastic count(1,2). Although microplastics can be found throughout the oceanic water column(3,4), most studies collect microplastics from surface waters (less than about 50-cm depth) using net tows(5). Consequently, our understanding of the microplastics distribution across ocean depths is more limited. Here we synthesize depth-profile data from 1,885 stations collected between 2014 and 2024 to...
• The end of AIDS is in sight: don't abandon PEPFAR now AI翻译
  作者：[Anonymous]
• Brief antibiotic use drives human gut bacteria towards low-cost resistance AI翻译
  作者：Yaffe, Eitan; Dethlefsen, Les; Patankar, Arati V.; Gui, Chen; Holmes, Susan; Relman, David A.
  作者单位：Stanford University; US Department of Veterans Affairs; Veterans Health Administration (VHA); VA Palo Alto Health Care System; Stanford University; Stanford University
  摘要：Understanding the relationship between antibiotic use and the evolution of antimicrobial resistance is vital for effective antibiotic stewardship. Yet, animal models and in vitro experiments poorly replicate real-world conditions1. To explain how resistance evolves in vivo, we exposed 60 human participants to ciprofloxacin and used longitudinal stool samples and a new computational method to assemble the genomes of 5,665 populations of commensal bacterial species within participants. Analysis ...
• Perception of viral infections and initiation of antiviral defence in rice AI翻译
  作者：Huang, Yu; Yang, Jialin; Sun, Xi; Li, Jiahao; Cao, Xiaoqiang; Yao, Shengze; Han, Yanhong; Chen, Changtian; Du, Linlin; Li, Shuo; Ji, Yinghua; Zhou, Tong; Wang, He; Han, Jia-jia; Wang, Wenming; Wei, Chunhong; Xie, Qi; Yang, Zhirui; Li, Yi
  作者单位：Peking University; Peking University; Fujian Agriculture & Forestry University; Chinese Academy of Sciences; Institute of Genetics & Developmental Biology, CAS; Chinese Academy of Sciences; University of Chinese Academy of Sciences, CAS; Jiangsu Academy of Agricultural Sciences; Sichuan Agricultural University; Yunnan University; China Agricultural University; Sichuan Academy of Agricultural Sciences (SAAS)
  摘要：Crop production faces persistent threats from insect-vector-borne viral diseases1,2. Recent advancements have revealed the intricate immune mechanisms that plants deploy against viral pathogens3, 4, 5, 6, 7-8. However, the molecular mechanisms through which plant hosts recognize viral infections and initiate antiviral defence at disease onset have not been elucidated. Here, through the natural infection of rice by inoculation with insect vectors carrying the natural forms of viruses, we show t...
• Atomic lift-off of epitaxial membranes for cooling-free infrared detection AI翻译
  作者：Zhang, Xinyuan; Ericksen, Owen; Lee, Sangho; Akl, Marx; Song, Min-Kyu; Lan, Haihui; Pal, Pratap; Suh, Jun Min; Lindemann, Shane; Jung-El Ryu; Shao, Yanjie; Zheng, Xudong; Han, Ne Myo; Bhatia, Bikram; Kim, Hyunseok; Kum, Hyun S.; Chang, Celesta S.; Shi, Yunfeng; Eom, Chang-Beom; Kim, Jeehwan
  作者单位：Massachusetts Institute of Technology (MIT); University of Wisconsin System; University of Wisconsin Madison; Massachusetts Institute of Technology (MIT); Rensselaer Polytechnic Institute; Massachusetts Institute of Technology (MIT); Massachusetts Institute of Technology (MIT); Massachusetts Institute of Technology (MIT); University of Louisville; University of Illinois System; University of Illinois Urbana-Champaign; Yonsei University; Seoul National University (SNU); Massachusetts Institute of Technology (MIT)
  摘要：Recent breakthroughs in ultrathin, single-crystalline, freestanding complex oxide systems have sparked industry interest in their potential for next-generation commercial devices1,2. However, the mass production of these ultrathin complex oxide membranes has been hindered by the challenging requirement of inserting an artificial release layer between the epilayers and substrates3,4. Here we introduce a technique that achieves atomic precision lift-off of ultrathin membranes without artificial ...
• Twenty years of genome-wide association studies AI翻译
  作者：Southam, Lorraine; Zeggini, Eleftheria
  作者单位：Technical University of Munich
• Granzyme K activates the entire complement cascade AI翻译
  作者：Donado, Carlos A.; Theisen, Erin; Zhang, Fan; Nathan, Aparna; Fairfield, Madison L.; Rupani, Karishma Vijay; Jones, Dominique; Johannes, Kellsey P.; Accelerating Med Partnership RA SLE Network, Christopher; Raychaudhuri, Soumya; Dwyer, Daniel F.; Jonsson, A. Helena; Brenner, Michael B.
  作者单位：Harvard University; Harvard University Medical Affiliates; Brigham & Women's Hospital; Harvard University; Harvard Medical School; Harvard University; Harvard University Medical Affiliates; Brigham & Women's Hospital; University of Colorado System; University of Colorado Anschutz Medical Campus; University of Colorado System; University of Colorado Anschutz Medical Campus; Harvard University; Harvard University Medical Affiliates; Brigham & Women's Hospital; Harvard University; Harvard Medical School; Harvard University; Harvard University Medical Affiliates; Brigham & Women's Hospital; Harvard University; Massachusetts Institute of Technology (MIT); Broad Institute; University of Colorado System; University of Colorado Anschutz Medical Campus; Harvard University; Harvard University Medical Affiliates; Brigham & Women's Hospital
  摘要：Granzymes are a family of serine proteases that are mainly expressed by CD8+ T cells, natural killer cells and innate-like lymphocytes1. Although their primary function is thought to be the induction of cell death in virally infected cells and tumours, accumulating evidence indicates that some granzymes can elicit inflammation by acting on extracellular substrates1. We previously found that most tissue CD8+ T cells in rheumatoid arthritis synovium, and in inflamed organs for some other disease...