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作者：Vahle, Patricia; Vallari, Zoya
作者单位：University System of Ohio; Ohio State University
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作者：Wei, Qi; Peter, Jonah S.; Ren, Hui; Wang, Weizhen; Zhou, Luwei; Liu, Qi; Ostermann, Stefan; Yin, Jun; Cai, Songhua; Yelin, Susanne F.; Li, Mingjie
作者单位：Hong Kong Polytechnic University; Harvard University; Harvard University; Harvard University; Hong Kong Polytechnic University; Hong Kong Polytechnic University
摘要：Superfluorescence (SF) is the collective emission of intense, coherent light from an interacting ensemble of quantum emitters(1, 2, 3-4). Although SF has been observed in several solid-state materials(5, 6, 7-8), the spontaneous generation of circularly polarized SF from chiral materials (chiral SF) has not been realized(9,10). Here, we report the observation of chiral SF originating from edge states in large-area (>100 & micro;m & times; 100 & micro;m), vertically aligned chiral perovskite su...
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作者：Sun, Fangmiao; Lim, Kayla Y.; Dang, James; Zhang, Li I.; Wu, Ye Emily; Hong, Weizhe
作者单位：University of California System; University of California Los Angeles; David Geffen School of Medicine at UCLA; University of California Los Angeles Medical Center; University of California System; University of California Los Angeles; David Geffen School of Medicine at UCLA; University of California Los Angeles Medical Center; University of Southern California; University of California System; University of California Los Angeles
摘要：Humans and other animals can sense the negative states of other individuals and respond with prosocial helping behaviour to improve their conditions1,2. Although prosocial helping behaviour is proposed to have an evolutionary root in caring for vulnerable newborn offspring1,3, whether the neural substrates underlying parenting may contribute to adult-directed helping behaviours remains largely unclear. Here we show that mice with higher levels of parenting show more prosocial allogrooming towa...
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作者：Liu, Shuxian; Liu, Yusong; Xue, Junchao; Li, Zhenzhen; Zhang, Yan; Li, Bailun; Xu, Lidan; Li, Lili; Yu, Zhenzhen; Yu, Hongtao; Gao, Haishan; Shen, En-Zhi
作者单位：Zhejiang University; Westlake University; Westlake Laboratory; Westlake University; Fudan University; Westlake University; Westlake University; Army Medical University; Westlake University
摘要：Mammalian oocytes are filled with fibric structures called cytoplasmic lattice (CPL) that are essential for oocyte maturation and early embryonic development1, 2-3. CPL comprises subcortical maternal complex (SCMC) and multiple components, including PADI62,4,5. Although it was first discovered in the 1960s, the molecular architecture and assembly mechanisms of CPL remain poorly understood. Here we present the cryo-electron microscopy structure of CPL isolated from mouse oocytes. Our analysis i...
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作者：Liu, Shaocheng; Pols, Mike; Zhang, Zhongyang; Huang, Xudan; Huang, Zijian; Han, Ying; Guo, Zhenyu; Li, Liang; Fan, Rundong; Zhang, De-Yi; Ping, Du; Yu, Wenjin; Gu, Jiazhen; Men, Luxuan; Dong, Hao; Tao, Shuxia; Wang, Lifen; Chen, Qi; Wang, Huan; Xu, Huaiyu; Sun, Ling-Dong; Yan, Chun-Hua; Zhou, Huanping
作者单位：Peking University; Chinese Academy of Sciences; Eindhoven University of Technology; Chinese Academy of Sciences; Nanjing Institute of Geology & Paleontology, CAS; Institute of Physics, CAS; Beijing University of Technology; Beijing Institute of Technology; Chinese Academy of Sciences; University of Science & Technology of China, CAS; Peking University
摘要：Metal halide perovskites have emerged as promising semiconductors for light-emitting diodes (LEDs) owing to their excellent luminescence properties1. However, their performance remains limited, primarily owing to the inherent contradiction between 'high crystallinity' and 'small size' in the in situ synthesis of perovskite nanocrystals on substrates. Here we report efficient blue perovskite LEDs (PeLEDs) achieved via in situ polymerization-driven nanocrystal confinement to synthesize perovskit...
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作者：[Anonymous]
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作者：Schmuck, Alexandra; Bele, Tiago G. A.; Withoeck, Daniel; Van Geem, Kevin M.; Ragaert, Kim; De Meester, Steven
作者单位：Ghent University; University of Erlangen Nuremberg; Ghent University; Maastricht University
摘要：Increasing recycling rates requires not only better technologies but also smarter collection of plastic packaging waste1. Source separation-sorting materials such as plastics and metals at the household level-captures substantial waste volumes2,3, yet significant quantities still remain in the residual household waste fraction owing to misthrows and non-participation4,5. Post-sorting of mixed waste has been proposed as a one-bin alternative to boost capture6,7, despite concerns that contaminat...
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作者：Ren, Zhenning; Chhetri, Abhishek; Liu, Chang; Offner, ShuYu; Sharma, Kedar; Borgnia, Mario J.; Im, Wonpil; Yokoyama, Kenichi; Lee, Seok-Yong
作者单位：Duke University; Lehigh University; Lehigh University; Lehigh University; National Institutes of Health (NIH) - USA; NIH National Institute of Environmental Health Sciences (NIEHS); Duke University
摘要：Invasive fungal infections pose life-threatening risks to the increasing population of immunocompromised patients1,2. Treatment remains challenging due to limited antifungal drugs and increasing resistance. beta-1,3-d-glucan synthase (GS), comprising the catalytic Fks1 and the regulatory small GTPase, Rho1 (refs. 3,4), is the target of clinically important echinocandin antifungals. Despite recent studies5, 6-7, the mechanisms of GS catalysis, Rho1 regulation and echinocandin inhibition and res...
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作者：De Jonghe, Joachim; Kim, Hyung Chul; Adedeji, Ayanfeoluwa; Leitao, Elsa; Dawes, Ruebena; Kajba, Christina M.; Cogne, Benjamin; Chen, Yuyang; Blakes, Alexander J. M.; Simons, Cas; Rius, Rocio; Alvi, Javeria R.; Amblard, Florence; Austin-Tse, Christina; Baer, Sarah; Balton, Elsa V.; Blanc, Pierre; Calame, Daniel G.; Coutton, Charles; Cunningham, Chloe A.; Dargie, Nitsuh; Dipple, Katrina M.; Du, Haowei; El Chehadeh, Salima; Glass, Ian; Gleeson, Joseph G.; Grunewald, Olivier; Gueguen, Paul; Harbuz, Radu; Jacquemont, Marie-Line; Leventer, Richard J.; Marijon, Pierre; Messaoud, Olfa; Sultan, Tipu; Thauvin, Christel; Vincent-Delorme, Catherine; Yilmaz Gulec, Elif; Thevenon, Julien; Mendez, Rodrigo; MacArthur, Daniel G.; Depienne, Christel; Nava, Caroline; Whiffin, Nicola; Findlay, Gregory M.
作者单位：Francis Crick Institute; University of Oxford; University of Oxford; Wellcome Centre for Human Genetics; University of London; University College London; University of Duisburg Essen; Centre National de la Recherche Scientifique (CNRS); Institut National de la Sante et de la Recherche Medicale (Inserm); Nantes Universite; CHU de Nantes; Nantes Universite; Centre National de la Recherche Scientifique (CNRS); Institut National de la Sante et de la Recherche Medicale (Inserm); CHU de Nantes; University of Manchester; Garvan Institute of Medical Research; Murdoch Children's Research Institute; CHU Grenoble Alpes; Centre National de la Recherche Scientifique (CNRS); CNRS - National Institute for Biology (INSB); Harvard University; Massachusetts Institute of Technology (MIT); Broad Institute; CHU Strasbourg; Universites de Strasbourg Etablissements Associes; Universite de Strasbourg; University of Washington; University of Washington Seattle; Baylor College of Medicine; Baylor College of Medicine; Baylor College Medical Hospital; Murdoch Children's Research Institute; Victorian Clinical Genetics Services; University of Melbourne; University of Washington; University of Washington Seattle; Baylor College of Medicine; Universites de Strasbourg Etablissements Associes; CHU Strasbourg; Universite de Strasbourg; Universites de Strasbourg Etablissements Associes; Universite de Lorraine; Institut National de la Sante et de la Recherche Medicale (Inserm); Universite de Strasbourg; University of California System; University of California San Diego; Universite de Lille; Institut National de la Sante et de la Recherche Medicale (Inserm); CHU Lille; Universite de Lille; CHU Lille; CHU Tours; Universite de Tours; CHU Tours; Royal Children's Hospital Melbourne; Harvard University; Harvard Medical School; Universite Bourgogne Europe; CHU Dijon Bourgogne; Universite Bourgogne Europe; Institut Agro; Institut Agro Dijon; CHU Dijon Bourgogne; Institut National de la Sante et de la Recherche Medicale (Inserm); Universite Bourgogne Europe; Institut Agro; Institut Agro Dijon; Universite de Lille; CHU Lille; Istanbul Medeniyet University; Stanford University; Assistance Publique Hopitaux Paris (APHP); Institut National de la Sante et de la Recherche Medicale (Inserm); Centre National de la Recherche Scientifique (CNRS); Sorbonne Universite; Hopital Universitaire Pitie-Salpetriere - APHP
摘要：Recently, de novo variants in an 18-nucleotide region in the centre of RNU4-2 were shown to cause ReNU syndrome, a syndromic neurodevelopmental disorder that is predicted to affect tens of thousands of individuals worldwide1,2. RNU4-2 is a non-protein-coding gene that is transcribed into the U4 small nuclear RNA component of the major spliceosome3. ReNU syndrome variants disrupt spliceosome function and alter 5 ' splice site selection1,4. Here we performed saturation genome editing (SGE) of RN...
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作者：Castelvecchi, Davide
