作者：Varilly, Patrick; Schifferli, Mark; Yang, Katherine; Cronan, Paul; Specht, Ivan; Burcham, Tim; Glennon, Olivia; Jacks, Olivia; Laning, Ellory; Marrs, Libby; Oba, Kyle; Yeung, Shannon; Zhao, Karlie Wenran; Parker, Edyth; Omah, Ifeanyi; Pekar, Jonathan E.; Luebbert, Laura; Andersen, Kristian G.; Park, Daniel J.; Schaffner, Stephen F.; MacInnis, Bronwyn L.; Happi, Christian; Lemieux, Jacob E.; Ozonoff, Al; Mitzenmacher, Michael; Fry, Ben; Sabeti, Pardis C.
摘要：Pathogen genomic analysis is central to tracking, understanding and containing outbreaks1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12-13, but the complexity and cost of state-of-the-art phylogenetic tools limit global access and impact. Here we introduce Delphy, an exact reformulation of Bayesian phylogenetics14, 15, 16-17 designed to transform its speed, scalability and accessibility while retaining Bayesian state-of-the-art accuracy. Delphy's central data structure, an explicit mutation-annotated tr...
作者：Havdahl, Alexandra Karoline; Corfield, Elizabeth C.
作者单位：Norwegian Institute of Public Health (NIPH); University of Bristol
作者：Zukowski, Alan; Stepien, Martyna
作者单位：Polish Academy of Sciences; University of Wroclaw
