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作者:Petrini, Alessandro; Conti, Claudio; Pierangeli, Davide
作者单位:Sapienza University Rome; Sapienza University Rome; Consiglio Nazionale delle Ricerche (CNR); Istituto dei Sistemi Complessi (ISC-CNR)
摘要:Spatial light modulation is a cornerstone of modern photonics. Crucial advances in photonic information processing1, 2-3 rely on the spatial manipulation of the optical phase4, 5, 6, 7, 8, 9, 10, 11-12 and state of polarization (SOP)13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26-27. The degree of polarization (DOP)28, 29-30 is a fundamental property that can serve as an extra resource. However, no technology exists at present that can spatially modulate the DOP in a programmable manner...
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作者:Robinson, Andrew
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作者:Wu, Canrong; Jin, Sanshan; Xu, Jiuyin; Wang, James Jiqi; Guo, Xiaoqi; Li, Yunhai; Cao, Zhenyu; Jiang, Mengting; Yuan, Qingning; Hu, Wen; Li, Changyao; Xu, Youwei; Wang, Ming-Wei; Jiang, Yi; Xu, H. Eric
作者单位:Shanghai Jiao Tong University; Lin Gang Laboratory; ShanghaiTech University; Huazhong University of Science & Technology; Huazhong University of Science & Technology; Nanjing Medical University; Xiamen University; Nanjing University of Chinese Medicine; Chinese Academy of Sciences; Shanghai Institute of Materia Medica, CAS; Chinese Academy of Sciences; University of Chinese Academy of Sciences, CAS
摘要:Glycosphingolipids are essential membrane components that organize lipid microdomains and orchestrate cellular signalling, differentiation and neuronal function1, 2, 3-4. In humans, these functions arise from a repertoire of several hundred glycosphingolipid species generated through stepwise glycan elaboration5,6. Entry into this network is controlled by a single committed reaction catalysed by UDP-glucose ceramide glucosyltransferase (UGCG), the gatekeeper that dictates the scale and composi...
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作者:Pelaz, Sara G.; Mitsui, Katsukuni; Kolosowska, Natalia; Fritch, Haley; Neupane, Chiranjivi; Casha, Vanessa H.; Alonso-Gardon, Marta; Pandey, Vijaya; Wang, Lizheng; Kawaguchi, Riki; Wohlschlegel, James A.; Guo, Jiami; McCarroll, Steven A.; Berretta, Sabina; Khakh, Baljit S.
作者单位:University of California System; University of California Los Angeles; David Geffen School of Medicine at UCLA; University of California Los Angeles Medical Center; Harvard University; Harvard University Medical Affiliates; McLean Hospital; Harvard University; Harvard Medical School; Harvard University; Massachusetts Institute of Technology (MIT); Broad Institute; University of California System; University of California Los Angeles; David Geffen School of Medicine at UCLA; University of California Los Angeles Medical Center; University of Calgary; University of California System; University of California Los Angeles; David Geffen School of Medicine at UCLA; University of California Los Angeles Medical Center; University of California System; University of California Los Angeles; Howard Hughes Medical Institute; Harvard University; Harvard Medical School; University of California System; University of California Los Angeles; David Geffen School of Medicine at UCLA; University of California Los Angeles Medical Center; Cardiff University
摘要:Understanding how adverse life events trigger stress-related behavioural changes remains an unresolved challenge. The amygdala is integral to emotion and stress responses1 and comprises astrocytes, neurons and other cells. Here we show that amygdala astrocytes contribute to stress-related behaviours through signalling mechanisms related to their primary cilia2. Amygdala astrocytes are altered during stress at the protein and gene expression level, display reduced expression of molecules relate...
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作者:Zhu, Zheng; Zhang, Peiqi; Gao, Bin; Ly, Kit San; Tao, Hongyi; Fu, Yiyi; Lin, Zhenyang; Quan, Yangjian
作者单位:Hong Kong University of Science & Technology; Chinese University of Hong Kong
摘要:Migration is a fundamental chemical transformation. Beyond scientific curiosity and mechanistic intrigue, migration reactions offer approaches to remote or otherwise challenging reaction sites, complementary to traditional synthetic methodologies1. While single-site migration has been extensively studied with great regioselectivity control, orchestrating the concurrent migration of two distant sites along a carbon chain remains largely unexplored2,3. This is primarily due to the exponentially ...
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作者:Shen, Yuan; Yu, Linghua
作者单位:Zhejiang University
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作者:Wu, Zhenlin; Duka, Tim; Isaza-Monsalve, Mariano; Kautzky, Miriam; Svarc, Vojtech; Turci, Andrea; Nardi, Rene; Gronowski, Marcin; Tomza, Michal; Furey, Brandon J.; Schindler, Philipp
作者单位:University of Innsbruck; Palacky University Olomouc; University of Warsaw
摘要:Absorption spectroscopy is a fundamental tool for probing molecular structure1. However, performing absorption spectroscopy on individual molecules is challenging because of the low signal-to-noise ratio2,3. Here we report on non-destructive absorption spectroscopy on a mid-infrared vibrational transition in a single molecular ion that is co-trapped with an atomic ion. The absorption of a single photon is detected by the momentum transfer from the absorbed photon onto the molecule. This recoil...
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作者:Zhu, Sihui; Tang, Haibao; Jones, Tyler; Fumia, Nathan; Zhou, Jing; Cai, Lingmin; Wang, Wen; Zhou, Yanhong; Mao, Haoming; Zuo, Liping; Zheng, Yutong; Zhang, Yixing; Ji, Zhaoqian; Tao, Huanhuan; Pan, Jianling; Xu, Yating; Chen, Huiru; Nagai, Chifumi; Ming, Ray
作者单位:Fujian Agriculture & Forestry University
摘要:Variations of meiosis, which normally halve genetic complements prior to fertilization, can have profound consequences. For example, whole-genome duplications (polyploidy) have shaped the evolution and diversification of most angiosperm lineages. The century-long success of sugarcane interspecific hybrids has been attributed to unusual female restitution-an unreduced maternal gamete fusing with a normal haploid paternal gamete1,2. Here we generated haplotype-resolved genomes of octoploid Sacch...
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作者:King, Anthony
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作者:[Anonymous]