6773期

最新文章

• Shrinking interconnects beyond copper AI翻译
  作者：Kiani, Mehrdad T.; Cha, Judy J.
  作者单位：State University System of Florida; Florida State University; Cornell University
• Advancing research on financial stability and climate-related financial risk AI翻译
  作者：Pizer, William; Stock, James
  作者单位：Resources for the Future; Harvard University; Harvard University
• Unbiased discovery of neuronal architectures AI翻译
  作者：Squair, Jordan W.; Skinnider, Michael A.; Courtine, Gregoire
  作者单位：Swiss Federal Institutes of Technology Domain; University of Lausanne; Ecole Polytechnique Federale de Lausanne; Centre Hospitalier Universitaire Vaudois (CHUV); University of Lausanne; Centre Hospitalier Universitaire Vaudois (CHUV); University of Lausanne; Swiss Federal Institutes of Technology Domain; Ecole Polytechnique Federale de Lausanne; Princeton University; Princeton University; Ludwig Institute for Cancer Research
• AI hallucinates because it's trained to fake it till it makes it AI翻译
  作者：Zhao, Celina
• Frankenstein; or, The Modern Prometheus AI翻译
  作者：Greenbaum, Dov
  作者单位：Reichman University; Reichman University
• Adipogenin promotes the development of lipid droplets by binding a dodecameric seipin complex AI翻译
  作者：Li, Chao; Sun, Xue-Nan; Funcke, Jan-Bernd; Vanharanta, Lauri; Prasanna, Xavier; Gov, Kaitlynn; Li, Yan; Virostek, Megan; Joung, Chanmin; Joffin, Nolwenn; Kanerva, Kristiina; Szkalisity, Abel; Kulig, Waldemar; Straub, Leon; Chen, Shiuhwei; Velasco, Joselin; Cobb, Ayanna; La Padula, Davide; Wang, May-Yun; Onodera, Toshiharu; Voros, Csaba; Kim, Dae-Seok; Kim, Min; Varlamov, Oleg; Li, Yang; Liu, Chen; Nawrocki, Andrea R.; Zhao, Shangang; Oh, Da Young; Wang, Zhao V.; Gordillo, Ruth; Goodman, Joel M.; Wynn, R. Max; Henne, W. Mike; Vattulainen, Ilpo; Han, Yan; Ikonen, Elina; Scherer, Philipp E.
  作者单位：University of Texas System; University of Texas Southwestern Medical Center; University of Helsinki; University of Helsinki; University of Helsinki; University of Texas System; University of Texas Southwestern Medical Center; Magna Graecia University of Catanzaro; University of Osaka; University of Osaka; HUN-REN; HUN-REN Biological Research Center; Ulsan National Institute of Science & Technology (UNIST); Oregon Health & Science University; Oregon National Primate Research Center; University of Texas System; University of Texas Southwestern Medical Center; University of Texas System; University of Texas Southwestern Medical Center; Johnson & Johnson; Janssen Pharmaceuticals; University of Texas System; University of Texas at San Antonio; City of Hope; Beckman Research Institute of City of Hope; University of Texas System; University of Texas Southwestern Medical Center; University of Texas System; University of Texas Southwestern Medical Center; University of Texas System; University of Texas Southwestern Medical Center
  摘要：The microprotein adipogenin (Adig) is predominantly expressed in adipose tissues. Here, we found that Adig interacts with seipin to form a stable, rigid complex. We present the structure of the seipin-Adig complex at an overall resolution of similar to 3.0 angstroms. The structure revealed that mammalian seipin assembles into two distinct oligomeric forms: undecamers and dodecamers. Adig selectively bound to the dodecameric form and enhanced seipin assembly by bridging and stabilizing adjacent...
• Preventing hypocontractility-induced fibroblast expansion alleviates dilated cardiomyopathy AI翻译
  作者：Bretherton, Ross C.; Reichardt, Isabella M.; Zabrecky, Kristin A.; Nagle, Abigail; Bailey, Logan R. J.; Bugg, Darrian; Smolgovsky, Sasha; Gifford, Amy L.; Mcmillen, Timothy S.; Goldstein, Alex J.; Kooiker, Kristina B.; Flint, Galina V.; Martinson, Amy; Gunaje, Jagdambika; Koser, Franziska; Plaster, Elizabeth; Linke, Wolfgang A.; Regnier, Michael; Moussavi-Harami, Farid; Sniadecki, Nathan J.; Deforest, Cole A.; Davis, Jennifer
  作者单位：University of Washington; University of Washington Seattle; University of Washington; University of Washington Seattle; University of Washington; University of Washington Seattle; University of Washington; University of Washington Seattle; University of Washington; University of Washington Seattle; University of Washington; University of Washington Seattle; University of Washington; University of Washington Seattle; University of Munster; University of Washington; University of Washington Seattle; University of Washington; University of Washington Seattle; University of Washington; University of Washington Seattle; University of Washington; University of Washington Seattle; University of Washington; University of Washington Seattle; University of Washington; University of Washington Seattle
  摘要：Cardiomyocyte hypocontractility underlies inherited dilated cardiomyopathy (DCM). Yet, whether fibroblasts modify DCM phenotypes remains unclear despite their regulation of fibrosis, which strongly predicts disease severity. Expression of a hypocontractility-linked sarcomeric variant in mice triggered cardiac fibroblast expansion from the de novo formation of hyperproliferative mechanosensitized fibroblast states, which occurred prior to eccentric myocyte remodeling. Initially, this fibroblast...
• Platforms of power AI翻译
  作者：Garfinkel, Simson L.
  作者单位：Harvard University; National Institute of Standards & Technology (NIST) - USA
• Ultrafast inverse chirality-induced spin selectivity observed by THz emission AI翻译
  作者：Dong, Yifan; McConnell, Aeron; Hautzinger, Matthew P.; Haque, Md Azimul; Comstock, Andrew H.; Theiler, Pius M.; Luther, Joseph M.; Sercel, Peter C.; Sun, Dali; Beard, Matthew C.
  作者单位：United States Department of Energy (DOE); National Renewable Energy Laboratory - USA; University of California System; University of California Riverside; North Carolina State University; North Carolina State University; University of Colorado System; University of Colorado Boulder
  摘要：Chirality-induced spin selectivity (CISS) phenomena arise from an interplay among structural chirality, electron spin orientation, and charge current. Steady-state observations such as magnetoresistance offer little insight into the timescales that govern the spin-charge interconversion and often conflate interfacial and bulk phenomena. By contrast, inverse CISS involves the conversion of spin to a charge current. Using terahertz (THz) emission spectroscopy, we directly measured an ultrafast c...
• Multi-timescale frequency-phase matching for high-yield nonlinear photonics AI翻译
  作者：Mehrabad, Mahmoud Jalali; Xu, Lida; Moille, Gregory; Flower, Christopher J.; Sarkar, Supratik; Padhye, Apurva; Ou, Shao-Chien; Suarez-Forero, Daniel G.; Ghafariasl, Mahdi; Chembo, Yanne; Srinivasan, Kartik; Hafezi, Mohammad
  作者单位：University System of Maryland; University of Maryland College Park; National Institute of Standards & Technology (NIST) - USA; University System of Maryland; University of Maryland College Park
  摘要：Integrated nonlinear photonics struggles to deliver wafer-scale functional device yields: Nanometer-level fabrication variations compromise the strict frequency-phase matching mandated by energy- and momentum-conserving nonlinear processes. We introduce nested frequency-phase matching, a passive scheme that relaxes these constraints, and implement it in a two-timescale lattice of commercially available silicon nitride (SiN) coupled ring resonators for harmonic generation. The nested lattice si...