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作者:Bernhart, Erik; Rohrle, Marvin; Singh, Vijay Pal; Mathey, Ludwig; Amico, Luigi; Ott, Herwig
作者单位:RPTU University Kaiserslautern; RPTU University Kaiserslautern; Technology Innovation Institute; University of Hamburg; University of Hamburg; University of Hamburg; University of Catania; Istituto Nazionale di Fisica Nucleare (INFN)
摘要:The current-voltage characteristic of a driven superconducting Josephson junction displays discrete steps. This phenomenon, called the Shapiro steps, forms today's voltage standard. In this work, we report the observation of Shapiro steps in a driven Josephson junction in a gas of ultracold atoms. We demonstrate that the steps exhibit universal features and provide insight into the microscopic dissipative dynamics that we directly observe in the experiment. We find that the steps are directly ...
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作者:Gao, Shuo; Shao, Qinglong
作者单位:Chinese Academy of Sciences; University of Science & Technology of China, CAS; University of Oxford; Sun Yat Sen University
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作者:Jervis, Dylan; Girard, Marianne; MacLean, Jean-Philippe W.; Marshall, David; McKeever, Jason; Strupler, Mathias; Ramier, Antoine; Tarrant, Ewan; Young, David; Maasakkers, Joannes D.; Aben, Ilse; Scarpelli, Tia R.
摘要:Methane emissions from energy sector facilities (oil, gas, and coal) represent a substantial contribution to greenhouse gas emissions with substantial mitigation potential. We estimated global 2023 methane emissions from energy sector point sources using the high spatial resolution GHGSat satellite constellation. GHGSat detected 8.30 +/- 0.24 million tonnes per year of methane emissions from 3114 emission sites. Detected oil and gas- and coal-emitting sites were found to be emitting 16 and 48%...
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作者:Krammer, Sorin M. S.
作者单位:University of Southampton
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作者:Vernimmen, Tim
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作者:Nguyen, Tuan-Anh; Lin, Jung-Ming G.; Marques, Anne-Sophie M. C.; Fottner, Maximilian; Bauer, Ludwig G.; Reicher, Andreas; Daum, Diana; Scrofani, Lorenzo; Liu, Yusi; Cheng, Carol; D'Angelo, L. d. D. Luna; Sanchez, Juan; Bueschl, Christoph; Marella, Nara; Buphamalai, Pisanu; Traversi, Florian; Beres, Masa; Moll, Herwig P.; Siklos, Marton; Genger, Jakob-Wendelin; Hofstaetter, Gerald; Villanti, Ludovica; Malik, Monika; Klimek, Christoph; Runggatscher, Kathrin; Guertl, Bettina; Hansen, Jesper S.; Dobner, Sarah; Babosova, Olga; Becirovic, Tina; de Rooij, Laura P. M. H.; Casanova, Emilio; Koren, Anna; Froese, D. Sean; Rosenblatt, David S.; Klavins, Kristaps; Bergthaler, Andreas; Menche, Jorg; Hannich, J. Thomas; Abele, Miriam; Sdelci, Sara; Lang, Kathrin; Huber, Kilian V. M.; Kubicek, Stefan
作者单位:Austrian Academy of Sciences; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences; University of Oxford; University of Oxford; Swiss Federal Institutes of Technology Domain; ETH Zurich; University of Zurich; University Children's Hospital Zurich; University Children's Hospital Zurich; University of Zurich; Medical University of Vienna; Medical University of Vienna; Medical University of Vienna; Ludwig Boltzmann Institute; McGill University; Medical University of Vienna; Pompeu Fabra University; Barcelona Institute of Science & Technology; Centre de Regulacio Genomica (CRG)
摘要:Folate metabolism is intricately linked to purine de novo synthesis through the incorporation of folate-derived one-carbon units into the purine scaffold. By investigating chemical and genetic dependencies caused by mutations in methylenetetrahydrofolate dehydrogenase, cyclohydrolase, and formyltetrahydrofolate synthetase 1 (MTHFD1), we discovered a key role for Nudix hydrolase 5 (NUDT5) in regulating purine de novo synthesis. Genetic depletion and selective chemical degradation showed that a ...
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作者:Gaylord, Eliza A.; Foecke, Mariko H.; Samuel, Ryan M.; Soygur, Bikem; Detweiler, Angela M.; Mcintyre, Tara I.; Dorman, Leah C.; Borja, Michael; Laird, Amy E.; Arjyal, Ritwicq; Du, Juan; Gardner, James M.; Neff, Norma; Fattahi, Faranak; Laird, Diana J.
作者单位:University of California System; University of California San Francisco; University of California System; University of California San Francisco; University of California System; University of California San Francisco; University of California System; University of California San Francisco; Buck Institute for Research on Aging; Chan Zuckerberg Initiative (CZI); Portland State University; Oregon Health & Science University; University of California System; University of California San Francisco; University of California System; University of California San Francisco; University of California System; University of California San Francisco; University of California System; University of California San Francisco
摘要:The mouse is a tractable model for human ovarian biology; however, its utility is limited by incomplete understanding of how transcription and signaling differ interspecifically and with age. We compared ovaries between species using three-dimensional imaging, single-cell transcriptomics, and functional studies. In mice, we mapped declining follicle numbers and oocyte competence during aging; in human ovaries, we identified cortical follicle pockets and decreases in density. Oocytes had specie...
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作者:Servick, Kelly
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作者:Valencia-Montoya, Wendy A.; Lienard, Marjorie A.; Rosser, Neil; Calonje, Michael; Salzman, Shayla; Tsai, Cheng-Chia; Yu, Nanfang; Carlson, John R.; Cogni, Rodrigo; Pierce, Naomi E.; Bellono, Nicholas W.
作者单位:Harvard University; Harvard University; Harvard University; University of Liege; University of Miami; University System of Georgia; University of Georgia; Columbia University; Yale University; Universidade de Sao Paulo
摘要:Color and scent are well-known pollinator cues. Some plants also produce heat, but its role remains unclear. Here, we report that plant-generated thermal infrared radiation serves as a pollination signal and describe the underlying mechanisms of heat production and infrared detection. Mitochondrial adaptations heat plant reproductive structures in a circadian pattern, radiating infrared that is sufficient to attract beetle pollinators. Beetle antennae contain infrared-activated neurons with th...
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作者:Van Kerkhove, Maria D.; Ihekweazu, Chikwe
作者单位:World Health Organization; World Health Organization