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作者：Pan, Grace A.; Segedin, Dan Ferenc; TenHuisen, Sophia F. R.; Bhatt, Lopa; LaBollita, Harrison; Jiang, Abigail Y.; Song, Qi; Turkiewicz, Ari B.; Baykusheva, Denitsa R.; Nag, Abhishek; Agrestini, Stefano; Zhou, Ke-Jin; Pelliciari, Jonathan; Bisogni, Valentina; Zhou, Hua; Dean, Mark P. M.; Paik, Hanjong; Muller, David A.; Kourkoutis, Lena F.; Brooks, Charles M.; Mitrano, Matteo; Botana, Antia S.; Goodge, Berit H.; Mundy, Julia A.
作者单位：Harvard University; Harvard University; Cornell University; Arizona State University; Arizona State University-Tempe; Diamond Light Source; United States Department of Energy (DOE); Brookhaven National Laboratory; United States Department of Energy (DOE); Argonne National Laboratory; United States Department of Energy (DOE); Brookhaven National Laboratory; Cornell University; Cornell University; Max Planck Society
摘要：The discovery of superconductivity in square-planar nickelates has offered a rich materials platform to explore the origins of high-temperature superconductivity. However, experimental investigations have largely been limited to the infinite-layer RNiO2 (R, rare earth) nickelates. We constructed a phase diagram of multilayer square-planar Ndn+1NinO2n+2 compounds and found signatures of superconductivity for dimensionality n = 4 to 8. Upon decreasing n, the superconducting anisotropy evolves ow...
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作者：Winge, Marten C. G.; Jackrazi, Leandra V.; Porter, Douglas F.; Srinivasan, Suhas; Lopez-Pajares, Vanessa; Li, Dayan J.; Pham, Benjamin; Houser, Aubrey; Cha, Spencer H.; Meyers, Robin M.; Ko, Lisa A.; Ducoli, Luca; Miao, Weili; Meservey, Lindsey M.; Zarnegar, Brian J.; Smith, Mark; Ji, Andrew L.; Longaker, Michael T.; Khavari, Paul A.
作者单位：Stanford University; Stanford University; Stanford University; Stanford Medicine; Icahn School of Medicine at Mount Sinai; Amgen; Stanford University; US Department of Veterans Affairs; Veterans Health Administration (VHA); VA Palo Alto Health Care System
摘要：Stratified epithelial differentiation involves transcriptional and proteomic remodeling. Here, multiomic profiling implicated ubiquitin and related posttranslational networks in differentiation dynamics. Systematic perturbation of ubiquitin-like machinery in primary human keratinocytes which uncovered opposite functions of neural-precursor-cell-expressed, developmentally down-regulated 8 (NEDD8) and small ubiquitin-related modifier 2 (SUMO2). Generation of conditional knockout mice established...
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作者：Zhu, Yinjie; Wang, Xiaoxiong; Tong, Yifan; Jia, Chengzhen; Cao, Huansheng; Hu, Hongying; Tao, Yi
作者单位：Tsinghua University; Tsinghua University; Tsinghua University; Tsinghua University; Tsinghua University; Tsinghua Shenzhen International Graduate School; Tsinghua University; Tsinghua Shenzhen International Graduate School; Duke Kunshan University; Tsinghua University
摘要：Harmful algal blooms, the most severe ecological hazards worldwide, terminate abruptly within a few days. In this work, we identified that iron-catalyzed active lipid peroxides predominantly trigger individual cell ferroptosis and drive the population collapse of blooming cyanobacteria. We reveal the chronological sequence of labile iron burst, oxidative stress, lipid peroxidation, and cell death during a Microcystis bloom demise event. Dead cells exhibit a nonrandom spatial distribution withi...
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作者：Zeng, Biao; Roussos, Panos
作者单位：Icahn School of Medicine at Mount Sinai; Icahn School of Medicine at Mount Sinai; Icahn School of Medicine at Mount Sinai; Icahn School of Medicine at Mount Sinai; US Department of Veterans Affairs; Veterans Health Administration (VHA); James J. Peters VA Medical Center; US Department of Veterans Affairs; Veterans Health Administration (VHA); James J. Peters VA Medical Center
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作者：Crawford, Kate
作者单位：University of Southern California
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作者：Huang, Junhao; Tao, Hui; Chen, Sheng; Cui, Yahua; Xu, Yiran; Yan, Chuangye; Yan, Nieng
作者单位：Tsinghua University; Shenzhen Medical Academy of Research & Translation (SMART); Shenzhen Bay Laboratory
摘要：The chemical complexity and nontemplated biosynthesis of glycans have posed considerable challenges for establishing sequence-structure relationships. Here we report cryo-electron microscopy structures of tubular mastigonemes from a golden alga species, Ochromonas danica, in which a large number of N- and O-glycans are resolved at 1.8- to 2.2-angstrom resolution. Beyond high-mannose and complex N-glycans, we identify a noncanonical N-glycan on the Ala-Asn-Asp (AND) motif. The surface spikes co...
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作者：Lamers, K. P.; Ouwehand, J.; Ubels, R.; Nicolaus, M.; Camacho, C.; Potti, J.; Bell, F.; Burgess, M.; Lampe, H. M.; Nilsson, J. A.; Kerimov, A.; Ilyina, T.; Belskii, E.; Grinkov, V. G.; Sternberg, H.; Both, C.
作者单位：University of Groningen; Consejo Superior de Investigaciones Cientificas (CSIC); CSIC - Estacion Biologica de Donana (EBD); University of Exeter; Royal Society for Protection of Birds; University of Oslo; Lund University; Lomonosov Moscow State University; Russian Academy of Sciences; Institute of Plant & Animal Ecology of the Russian Academy of Sciences; Lomonosov Moscow State University
摘要：Migratory birds connect ecosystems worldwide and often show connectivity between breeding and nonbreeding areas, meaning that individuals have nonbreeding (wintering) locations close to others from the same breeding population. Although much work has characterized migration routes, we know little about what determines nonbreeding areas. We tracked pied flycatchers (Ficedula hypoleuca) from their entire breeding range and identified population-specific nonbreeding areas. Using an egg translocat...
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作者：Shubin, Neil H.
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作者：Yuan, Qian
作者单位：Texas A&M University System; Texas A&M University College Station
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作者：Hutson, Matthew
