6808期

最新文章

• The rise and fall of the Amazon Soy Moratorium AI翻译
  作者：Rausch, Lisa; Reis, Tiago N. P.; Mazzetti, Cristiane; Barrozo, Marcos; Skidmore, Marin; Gibbs, Holly K.
  作者单位：University of Wisconsin System; University of Wisconsin Madison; DePaul University; University of Illinois System; University of Illinois Urbana-Champaign
• NSF bans almost all research collaborations with China AI翻译
  作者：Mervis, Jeffrey
• AI in scientific publishing: Slower, worse, and more expensive AI翻译
  作者：Thorp, H. Holden
• The Therabot will see you now AI翻译
  作者：Jacobson, Nicholas C.
  作者单位：Dartmouth College
• In Other Journals AI翻译
  作者：Maroso, Mattia
• A transcriptional biosensor reveals mechanisms of α-ketoglutarate signaling to chromatin AI翻译
  作者：Sternisha, Alex C.; Li, Haocheng; Gajendra, Kumar; Xiao, Yi; Zhao, Xin; Traylor, Jeffrey I.; Guo, Lei; Jun, Ji Hyung; Fleishman, Morgan; Shipman, Tracey; Puliyappadamba, Vinesh T.; Kaphle, Pranita; Ouyang, Qing; Schmidt, Michael; Shi, Diana D.; Savani, Milan R.; Tsai, Alexander C. -Y.; Lee, Joyce H.; Gordillo, Ruth; Garcia-Bermudez, Javier; Kim, Yoon Jung; Tso, Shih-Chia; Brautigam, Chad A.; Zacharias, Lauren G.; Mathews, Thomas P.; Xu, Lin; Doench, John G.; Koduri, Vidyasagar; Abdullah, Kalil G.; Agathocleous, Michalis; Banaszynski, Laura A.; DeBerardinis, Ralph J.; Morrow, Eric M.; McBrayer, Samuel K.
  作者单位：University of Texas System; University of Texas Southwestern Medical Center; University of Texas System; University of Texas Southwestern Medical Center; Brown University; Brown University; Brown University; University of Texas System; University of Texas Southwestern Medical Center; University of Texas System; University of Texas Southwestern Medical Center; University of Texas System; University of Texas Southwestern Medical Center; University of Texas System; University of Texas Southwestern Medical Center; University of Texas System; University of Texas Southwestern Medical Center; Mass General Brigham; Harvard University; Harvard Medical School; Harvard University; Harvard University Medical Affiliates; Massachusetts General Hospital; Harvard University; Harvard Medical School; Harvard University Medical Affiliates; Dana-Farber Cancer Institute; University of Texas System; University of Texas Southwestern Medical Center; University of Texas System; University of Texas Southwestern Medical Center; University of Texas System; University of Texas Southwestern Medical Center; University of Texas System; University of Texas Southwestern Medical Center; Harvard University; Massachusetts Institute of Technology (MIT); Broad Institute; Harvard University; Harvard Medical School; Harvard University Medical Affiliates; Brigham & Women's Hospital; Pennsylvania Commonwealth System of Higher Education (PCSHE); University of Pittsburgh; Pennsylvania Commonwealth System of Higher Education (PCSHE); University of Pittsburgh; Howard Hughes Medical Institute; University of Texas System; University of Texas Southwestern Medical Center; University of Texas System; University of Texas Southwestern Medical Center; University of Texas System; University of Texas Southwestern Medical Center
  摘要：The metabolite alpha-ketoglutarate (alpha KG) is required for chromatin demethylation, but mechanisms that control alpha KG abundance in the nucleus are poorly defined. We designed a biosensor to monitor this metabolite pool in human cells using an alpha KG-responsive cyanobacterial transcription factor, NtcA, and used it to identify genes that regulate alpha KG in the nucleus. We defined an interorganelle pathway in which sequential mitochondrial activities of glutamic-pyruvic transaminase 2 ...
• Direct interaction of Vδ7 TCRs with IL17RA drives the differentiation of TH1-like γδT cells AI翻译
  作者：Ye, Kewei; Francis, Nimmy; Dunst, Josefine; Borgenstam, Amanda; Rocamonde-Lago, Iris; Koehler, Stefanie; You, Yuanyuan; Dubnovitsky, Anatoly; Kramer, Anja; Meng, Fanxi; Zollner, Valentin; Vogg, Lisa; Ryan, Tomas J.; Hanada, Ken-ichi; Regen, Tommy; Waisman, Ari; Malmstrom, Vivianne; Benson, Erik; Kisielow, Jan; Krey, Thomas; Winkler, Thomas H.; Hanke, Leo; Kreslavsky, Taras
  作者单位：Karolinska Institutet; Karolinska University Hospital; Karolinska Institutet; Karolinska University Hospital; University of Chicago; Karolinska Institutet; Karolinska University Hospital; SciLifeLab; Karolinska Institutet; University of Lubeck; Karolinska Institutet; Karolinska University Hospital; University of Erlangen Nuremberg; Trinity College Dublin; Trinity College Dublin; University of Melbourne; Florey Institute of Neuroscience & Mental Health; Canadian Institute for Advanced Research (CIFAR); National Institutes of Health (NIH) - USA; NIH National Cancer Institute (NCI); Johannes Gutenberg University of Mainz; Johannes Gutenberg University of Mainz; Hannover Medical School; German Center for Infection Research; Hannover Medical School
  摘要：Of the three classes of lymphocytes that constitute the adaptive immune system, gamma delta T cells are the only class for which the principles of antigen recognition remain enigmatic. Although endogenous gamma delta T cell antigen receptor (gamma delta TCR) ligands are thought to regulate gamma delta T cell development, their identities are largely elusive. Here, we identified the interleukin 17 receptor A chain (IL17RA) as a gamma delta TCR ligand that drove the differentiation of V delta 7+...
• Robust single-electron memory with quantum states manipulation AI翻译
  作者：Liu, Chunsen; Xiang, Yutong; Wang, Chong; Zhou, Peng
  作者单位：Fudan University
  摘要：The ultimate goal of information storage is single-electron memory. Quantum mechanics predicts that two distinguishable quantum states can be realized by confining a single electron within an ultrasmall space. However, scaling down such devices paradoxically amplifies fringe capacitance effects, which hinders the experimental observation of single-electron memory. We report a two-dimensional single-electron memory device based on a coplanar drain-channel-source structure that suppressed fringe...
• Reprogramming synthesis AI翻译
  作者：Zheng, Zhiling
  作者单位：Washington University (WUSTL)
• What tears can say AI翻译
  作者：Schwarz, Gavin