6814期

最新文章

• CURVED AIR AI翻译
  作者：Woolfson, Adrian
• Genomic predisposition is associated with the direction of sex chromosome evolution AI翻译
  作者：Zhou, Yang; Jin, Jiazheng; Jiang, Chuan; Dudchenko, Olga; Pinto, Brendan J.; Colaric, Zane; Khan, Ruqayya; Omer, Arina D.; Li, Xuemei; Song, Zhenzhen; Han, Li; Chen, Wanyi; Jiang, Lichun; Song, Zhangyue; Weisz, David; Xia, Yun; Qi, Yin; Cao, Zhengqing; Peng, Yudian; Zhu, Zexian; Zhou, Qi; Liu, Yan; Gu, Xiaosong; Nielsen, Stuart V.; Griffing, Aaron H.; Ezaz, Tariq; Georges, Arthur; Brennan, Ian; Aiden, Erez Lieberman; Gamble, Tony; Shi, Peng; Zhang, Guojie
  作者单位：Beijing Genomics Institute (BGI); Sun Yat Sen University; Sun Yat Sen University; University of Texas System; University of Texas Medical Branch Galveston; Rice University; Arizona State University; Arizona State University-Tempe; Chinese Academy of Sciences; University of Chinese Academy of Sciences, CAS; Skolkovo Institute of Science & Technology; Hunan Agricultural University; ShanghaiTech University; Chinese Academy of Sciences; Chengdu Institute of Biology, CAS; Northwest University Xi'an; South China Normal University; Zhejiang University; Zhejiang University; Nantong University; Nantong University; Louisiana State University System; Louisiana State University Shreveport; Princeton University; Princeton University; University of Canberra; University of Canberra; Australian National University; Rice University; Marquette University; University of Minnesota System; University of Minnesota Twin Cities; Chinese Academy of Sciences; Kunming Institute of Zoology, CAS; Chinese Academy of Sciences; Zhejiang University; Liangzhu Laboratory; National Institutes of Health (NIH) - USA; NIH National Human Genome Research Institute (NHGRI)
  摘要：Sex chromosome evolution is among the most dynamic genomic innovations in vertebrates, yet why some lineages evolve XY while others evolve ZW remains unclear. Using chromosome-level genomes from 19 geckos, we found that gecko sex chromosomes originated independently from 16 ancestral chromosomes. Their origins are nonrandom in both time and direction. Five of 11 datable origins coincide near the Middle Miocene Climatic Transition (similar to 10 million years ago). Ancestral gene content is ass...
• High-efficiency, long-lived lead-free perovskite light-emitting diodes AI翻译
  作者：Bai, Wenhao; Xuan, Tongtong; Ren, Guanhua; Song, Kunjie; Li, Huili; Hu, Chengkai; Mo, Fandi; Wang, Lixin; Xie, Rong-Jun
  作者单位：Xiamen University; Xiamen University; Xiamen University; Xiamen University; East China Normal University; Fudan University; Fudan University
  摘要：Tin halide perovskite light-emitting diodes (PeLEDs) offer promise due to their solution processability and low toxicity, yet low efficiency and poor stability hinder practical use. We found that electroluminescence failure in CsSnI3 is primarily driven by excessive hole injection-triggered electrochemical Sn2+ oxidation and an irreversible phase transition to Cs2SnI6. Through a dual-side optimization strategy combining formamidine doping with triphenylphosphine oxide modification to stabilize...
• Thermal cycling-induced nitriding increases energy-storage density in titanate ferroelectric films AI翻译
  作者：Yi, Jiaojiao; Zhong, Kangyu; Shen, Chen; Zhai, Yining; Sun, Lu; Zhang, Hongbin; Song, Zizheng; Chen, Zibin; Damjanovic, Dragan; Li, Jing-Feng; Zhang, Shujun; Liu, Lisha
  作者单位：Jiangsu University of Technology; Nanjing University of Science & Technology; Technical University of Darmstadt; Hong Kong Polytechnic University; Swiss Federal Institutes of Technology Domain; Ecole Polytechnique Federale de Lausanne; Tsinghua University; City University of Hong Kong; City University of Hong Kong
  摘要：Enhancing dielectric energy-storage density (Ue) requires maximizing the difference between maximum and remanent polarizations (Delta P). Improving Delta P remains fundamentally challenging, as existing strategies rarely achieve simultaneous high maximum polarization and low remanent polarization. We introduce a postsynthesis treatment method, cryogenic thermal cycling, in which liquid nitrogen infiltrates the film and then is rapidly cycled to 100 degrees C. This process markedly increases De...
• New chief of child health institute has MAHA ties AI翻译
  作者：Kaiser, Jocelyn
• Nonviral delivery of chemically modified tRNA rescues nonsense mutations in cystic fibrosis AI翻译
  作者：Chen, Jingan; Zhou, Muye; Dong, Songtao; Gong, Fanglin; Tennakoon, Rasangi; Seto, Breanna Y.; Chen, Ziyan Rachel; Zhou, Zhichang Peter; Pan, Jingyi; Xu, Yue; Luozhong, Sijin; Macarios, Colette Maya; Tijaro-Bulla, Santiago; Gonska, Tanja; Hu, Jim; Cui, Haissi; Li, Bowen
  作者单位：University of Toronto; University of Toronto; University of Toronto; University of Toronto; Hospital for Sick Children (SickKids); University of Toronto; University of Toronto; University of Toronto; University Health Network Toronto; Princess Margaret Cancer Centre
  摘要：Suppressor transfer RNAs (sup-tRNAs) can rescue disease-causing nonsense mutations by promoting readthrough of premature termination codons (PTCs). Their clinical translation is limited by suboptimal activity and inefficient in vivo delivery. In this work, we combined site-specific chemical modification of sup-tRNAs with cargo-tailored pulmonary lipid nanoparticle (LNP) engineering to overcome these barriers. Incorporation of N1-methyladenosine in sup-tRNAs improved PTC readthrough, enhanced t...
• Hypervision: An on-chip hyperspectral microsystem for online video-rate computational imaging AI翻译
  作者：Bian, Liheng; Meng, Qinghao; Li, Lianjie; Wang, Zhen; Feng, Yibo; Peng, Xuan; Zhao, Jiajun; Wang, Jingyi; Yang, Zhu; Zhang, Jun
  作者单位：Beijing Institute of Technology; Beijing Institute of Technology
  摘要：In this work, we tackled the long-standing challenge of the massive computation for hyperspectral imaging that is required to reconstruct and process large-volume spatial-spectral data cubes. Specifically, we designed a hardware accelerator, fabricated as a neural processing unit (NPU) capable of 9.3 tera operations per second at 16-bit integer (INT16), alongside a topology-aware structured pruning strategy for a lightweight reconstruction network. Through integration with our HyperspecI senso...
• Deep-sea mining outpaces both science and law AI翻译
  作者：Gao, Ji-Xi; Li, Hai-Dong; Zhao, Li-Jun; Tuoliewubieke, Dilinuer; Li, Ying-Kui; Shao, Ya-Mei
  作者单位：Nanjing Forestry University; Nanjing Forestry University; Nanjing Institute of Environmental Sciences, Ministry of Ecology & Environment; China Meteorological Administration; Institute of Desert Meteorology, China Meteorological Administration; China Meteorological Administration; University of Tennessee System; University of Tennessee Knoxville
• Hierarchical sensory processing in zebrafish thalamocortical-like circuits AI翻译
  作者：Trinh, Anh-Tuan; Ostenrath, Anna Maria; del Castillo-Berges, Ignacio; Cachin, Fanchon; Koc, Mina; Kraus, Susanne; Serneels, Bram; Kawakami, Koichi; Yaksi, Emre
  作者单位：Norwegian University of Science & Technology (NTNU); Norwegian University of Science & Technology (NTNU); Koc University; Research Organization of Information & Systems (ROIS); National Institute of Genetics (NIG) - Japan; Koc University
  摘要：Thalamocortical projections shape the functional regionalization and parallel sensory computations across the mammalian cortex. However, the principles of thalamocortical computations in nonmammalian vertebrates remain underexplored. In this work, we investigated how the zebrafish pallium, a homolog of the vertebrate cortex, receives and processes sensory information and how its architecture compares to thalamocortical circuits in other vertebrates. We revealed that the preglomerular complex (...
• Coral records suggest global warming is strengthening El Nino AI翻译
  作者：Vaz, Julia