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作者：THALL, PF; SIMON, R; ELLENBERG, SS
作者单位：National Institutes of Health (NIH) - USA; NIH National Cancer Institute (NCI)
摘要：A two-stage design which selects the best of several experimental treatments and compares it to a standard control is proposed. The design allows early termination with acceptance of the global null hypothesis. Optimal sample size and cut-off parameters are obtained by minimizing expected total sample size for fixed significance level and power.
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作者：VENZON, DJ; MOOLGAVKAR, SH
摘要：Several parametric families of relative risk functions have been proposed as models for matched case-control and survival data. Some advantages accrue to those in which relative risks are invariant under arbitrary translations of the origin of the covariate space, such as in the reassignment of values to dichotomous factors. It is shown in this paper that the family proposed by Guerrero and Johnson, which includes the commonly-used exponential and linear relative risk functions, has the simple...
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作者：CHRISTENSEN, R; JOHNSON, W
作者单位：University of California System; University of California Davis
摘要：The relationship between survival times and covariates is modelled via the accelerated failure time model with a Dirichlet process prior assumed for the underlying baseline survival function. Emphasis is placed on estimating the survival distribution for future individuals with given covariates. A method of estimating regression coefficients which uses the marginal distribution for observed censored data is given. The proposed procedures are shown to perform reasonably on two artificial data s...
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作者：MULLER, HG; STADTMULLER, U
作者单位：Ulm University
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作者：WALDEN, AT
摘要：An important problem in the physical sciences is estimation of the innovations of a noninvertible linear process. Here the problem of deconvolving such a time series containing a phase-lead is investigated. A compensating phase-lag filter is sought, and is estimated by maximization of a chosen statistic or projection index. It is demonstrated by simulation that a statistic which is superior to another in the ideal case of a full-band time series can be substantially inferior in the band-limite...
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作者：ROSENBAUM, PR
摘要：In observational studies, treated and control subjects may differ in ways that have not been observed, so that reference distributions for statistics that would be appropriate in randomized experiments may lead to incorrect inferences. A previous paper (Rosenbaum, 1987a) proposed a method for displaying the sensitivity of permutation inferences to bias due to an unobserved covariate in two cases: (i) the case of matched pairs, with arbitrary response variables, and (ii) the case of matching wi...
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作者：HOMMEL, G
摘要：Simes (1986) has proposed a modified Bonferroni procedure for the test of an overall hypothesis which is the combination of n individual hypotheses. In contrast to the classical Bonferroni procedure, it is not obvious how statements about individual hypotheses are to be made for this procedure. In the present paper a multiple test procedure allowing statements on individual hypotheses is proposed. It is based on the principle of closed test procedures (Marcus, Peritz and Gabriel, 1976) and con...
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作者：TIBSHIRANI, R
摘要：We investigate the use of a variance stabilizing transformation for the computation of a bootstrap t confidence interval. The transformation is estimated in an ''automatic'' manner through an initial bootstrap step. A bootstrap t interval is then computed for the variance stabilized parameter and the interval is mapped back to the original scale. The resultant procedure is second-order correct in some settings, invariant and in a number of examples it performs better than the usual untransform...
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作者：COX, DR; SOLOMON, PJ
作者单位：University of Adelaide
摘要：Methods are outlined for testing for serial correlation in large numbers of small samples, emphasis being placed on samples of size three. Some data on pulse rates are analyzed in illustration.
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作者：TONG, H
摘要：We have shown how a locally orthogonal reparameterization of an autoregressive model leads to the Levinson-Durbin algorithm.
