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作者：OMAN, SD; SEIDEN, E
摘要：Switch-back designs, originally proposed for cow lactation experiments, are repeated measurement designs appropriate for experiments in which the responses of experimental units vary with time according to different rates. A method for constructing such designs to compare an arbitrary number of treatments is presented, together with their analysis of variance. Robustness of the switch-back design when the treatments have residual as well as main effects is considered. Switch-back and balanced ...
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作者：TAM, SM
摘要：A probability sampling plan is suggested in this paper for drawing the sample so that the linear least-squares predictor of the total of a finite population is made asymptotically design-unbiased. Conditions are given for the sampling plan to reduce to the more familiar sample designs discussed in the literature.
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作者：TAWN, JA
摘要：Bivariate extreme value distributions arise as the limiting distributions of renormalized componentwise maxima. No natural parametric family exists for the dependence between the marginal distributions, but there are considerable restrictions on the dependence structure. We consider modelling the dependence function with parametric models, for which two new models are presented. Tests for independence, and discriminating between models, are also given. The estimation procedure, and the flexibi...
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作者：WEI, LJ
摘要：In comparing two treatments in a clinical trial, the randomized play-the-winner rule tends to assign more study subjects to the better treatment. It is applicable when patients have delayed responses to treatments. It is not deterministic and is less vulnerable to experimental bias than other adaptive designs. In this paper, an efficient algorithm is provided to construct exact permutation tests for testing the equality of the two treatments with the randomized play-the winner rule. The test p...
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作者：TSAI, WY
摘要：The maximum conditional likelihood estimator of the survival function with increasing hazard rate is derived, based on left truncated and right censored data. This estimator always exists, whereas the fully nonparametric conditional maximum likelihood estimator may not exist. A strong consistency theorem is established based on the total time on test transformation.
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作者：BOLSTAD, WM
摘要：This paper introduces biased perturbation distributions into the multiprocess dynamic linear model in order to represent growth hormone levels in animals, which are characteristically noisy pulsatile time series. The use of biased perturbation distributions allows a pulse to be detected on the first observation immediately after it occurs, thus allowing the process to be modelled in real time. This approach is found to be quite effective at detecting the occurrence of a pulse in growth hormone...
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作者：HOCHBERG, Y
摘要：A simple procedure for multiple tests of significance based on individual p-values is derived. This simple procedure is sharper than Holm''s (1979) sequentially rejective procedure. Both procedures contrast the ordered p-values with the same set of critical values. Holm''s procedure rejects an hypothesis only if its p-value and each of the smaller p-values are less than their corresponding critical-values. The new procedure rejects all hypothesis with smaller or equal p-values to that of any o...
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作者：BARNWAL, RK; PAUL, SR
摘要：Two C(.alpha.) statistics (Neyman, 1959) for testing the equality of the means of several groups of count data in the presence of a common dispersion parameter are derived. The performance of the two C(.alpha.) statistics, the likelihood ratio statistic and two more statistics based on transformed data (Anscombe, 1948) is then compared in terms of size and power by using Monte Carlo simulations. The C(.alpha.) statistics are recommended. The C(.alpha.) statistics for testing the equality of th...
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作者：MATTHEWS, DE
摘要：Methods described first by Madansky (1965) and revived more recently by Cox and Oakes (1984, pp. 51-2) are extended to incorporate the calculation of likelihood-based confidence intervals for functions of many parameters. Examples involving failure time data are used to illustrate the techniques.
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作者：DAVIDIAN, M; CARROLL, RJ; SMITH, W
作者单位：Texas A&M University System; Texas A&M University College Station; Eli Lilly; Lilly Research Laboratories; Eli Lilly; Lilly Research Laboratories
摘要：Assay data are often fitted by a nonlinear heteroscedastic regression model with the standard deviation of the response typically taken to be proportional to a power .theta. of the mean. For many assays, how one estimates .theta. does not greatly affect estimates of the mean regression function. Assay analysis also involves estimation of auxiliary calibration constructs such as minimum detectable concentration. An asymptotic theory is developed to show that standard methods for estimating .the...
