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作者：Moraga, Paula
作者单位：University of London; London School of Hygiene & Tropical Medicine
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作者：Roberts, Margaret E.; Stewart, Brandon M.; Airoldi, Edoardo M.
作者单位：University of California System; University of California San Diego; Princeton University; Harvard University
摘要：Statistical models of text have become increasingly popular in statistics and computer science as a method of exploring large document collections. Social scientists often want to move beyond exploration, to measurement and experimentation, and make inference about social and political processes that drive discourse and content. In this article, we develop a model of text data that supports this type of substantive research. Our approach is to posit a hierarchical mixed membership model for an...
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作者：Lee, Kyu Ha; Dominici, Francesca; Schrag, Deborah; Haneuse, Sebastien
作者单位：Harvard University; Harvard University Medical Affiliates; Forsyth Institute; Harvard University; Harvard School of Dental Medicine; Harvard University; Harvard T.H. Chan School of Public Health; Harvard University; Harvard University Medical Affiliates; Dana-Farber Cancer Institute
摘要：Readmission following discharge from an initial hospitalization is a key marker of quality of healthcare in the United States. For the most part, readmission has been studied among patients with acute health conditions, such as pneumonia and heart failure, with analyses based on a logistic-Normal generalized linear mixed model. Naive application of this model to the study of readmission among patients with advanced health conditions such as pancreatic cancer, however, is problematic because it...
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作者：Tavakoli, Shahin; Panaretos, Victor M.
作者单位：University of Cambridge; Swiss Federal Institutes of Technology Domain; Ecole Polytechnique Federale de Lausanne
摘要：Motivated by the problem of inferring the molecular dynamics of DNA in solution, and linking them with its base-pair composition, we consider the problem of comparing the dynamics of functional time series (FTS), and of localizing any inferred differences in frequency and along curvelength. The approath we take is one of Fourier analysis, where the complete second-order structure of the FTS is encoded by its spectral density operator, indexed by frequency and curvelength. The comparison is bro...
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作者：Guan, Qian; Laber, Eric B.; Reich, Brian J.
作者单位：North Carolina State University
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作者：Hannig, Jan; Iyer, Hari; Lai, Randy C. S.; Lee, Thomas C. M.
作者单位：University of North Carolina; University of North Carolina Chapel Hill; National Institute of Standards & Technology (NIST) - USA; University of California System; University of California Davis; University of Maine System; University of Maine Orono
摘要：R. A. Fisher, the father of modern statistics, proposed the idea of fiducial inference during the first half of the 20th century. While his proposal led to interesting methods for quantifying uncertainty, other prominent statisticians of the time did-not accept Fisher's approach as it became apparent that some of Fisher's bold claims about the properties of fiducial distribution did not hold up for multi-parameter problems. Beginning around the year 2000, the authors, and collaborators started...
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作者：Muller, Ulrich K.; Norets, Andriy
作者单位：Princeton University; Brown University
摘要：We consider the construction of set estimators that possess both Bayesian credibility and frequentist coverage properties. We show that under mild regularity conditions there exists a prior distribution that induces (1 - alpha) frequentist coverage of a (1 - alpha) credible set. In contrast to the previous literature, this result does not rely on asymptotic normality or invariance, so it can be applied in nonstandard inference problems. Supplementary materials for this article are available on...
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作者：Sengupta, Srijan; Volgushev, Stanislav; Shao, Xiaofeng
作者单位：Virginia Polytechnic Institute & State University; University of Toronto; University of Illinois System; University of Illinois Urbana-Champaign
摘要：The bootstrap is a popular and powerful method for assessing precision of estimators and inferential methods. However, for massive datasets that are increasingly prevalent, the bootstrap becomes prohibitively costly in computation and its feasibility is questionable even with modern parallel computing platforms. Recently, Kleiner and co-authors, proposed a method called BLB (bag of little bootstraps) for massive data, which is more computationally scalable with little sacrifice of statistical ...
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作者：Jentsch, Carsten; Kirch, Claudia
作者单位：University of Mannheim; Otto von Guericke University
摘要：This article is motivated by several articles that propose statistical inference where the independence of wavelet coefficients for both short- as well as long-range dependent time series is assumed. We focus on the sample variance and investigate the influence of the dependence between wavelet coefficients and this statistic. To this end, we derive asymptotic distributional properties of the sample variance for a time series that is synthesized, ignoring some or all dependence between wavelet...
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作者：Blocker, Alexander W.; Airoldi, Edoardo M.
作者单位：Harvard University
摘要：We consider the problem of estimating the genome-wide distribution of nucleosome positions from paired end sequencing data. We develop a modeling approach based on nonparametric templates to control for the variability along the sequence of read counts associated with nucleosomal DNA due to enzymatic digestion and other sample preparation steps, and we develop a calibrated Bayesian method to detect local concentrations of nucleosome positions. We also introduce a set of estimands that provides...
