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作者：PHADKE, MS; KEDEM, G
作者单位：University of Rochester
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作者：WOOD, CL; ALTAVELA, MM
作者单位：Cornell University
摘要：The asymptotic distributions of the Kolmogorov-Smirnov goodness-of-fit statistics are considered when the hypothesized distribution is discrete. Each of the statistics apparently has the same distribution as a continuous functional of an associated empirical process on the unit interval. Using known weak convergence properties for the empirical process, the asymptotic distributions of the Kolmogorov-Smirnov statistics are derived. A discussion and example are included.
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作者：ALI, MM
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作者：LAIRD, NM
作者单位：Harvard University
摘要：An empirical Bayes method for smoothing 2-way tables is presented. It is based on the use of the log linear model and a normal prior distribution. Estimation of the variance component in the prior is discussed, and 2 approximations are considered, 1 which utilizes the EM [expectation maximization] algorithm.
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作者：PRENTICE, RL; BRESLOW, NE
作者单位：Fred Hutchinson Cancer Center; University of Washington; University of Washington Seattle
摘要：The proportional hazards failure time model of Cox (1972) is adapted to the retrospective epidemiological study in which cases and controls are sampled from a population to relate disease incidence rates to exposure to suspected risk factors. The method permits simultaneous study of several exposure variables that may be discrete or continuous or a mixture of both, in the presence of additional explanatory variables and competing risks. The proportional hazards framework provides a fresh look ...
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作者：PRENTICE, RL
作者单位：University of Washington; University of Washington Seattle
摘要：Linear rank statistics are developed for tests on regression coefficients with censored data. These statistics arise as score statistics based on the marginal probability of a generalized rank vector. The observed Fisher information provides a variance estimator generally, while in certain special cases a permutation approach to variance estimation is also possible. The Wilcoxon test is generalized to regression tests with censored data. The log rank test is also produced as a special case.
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作者：MCKEAN, JW; HETTMANSPERGER, TP
作者单位：Pennsylvania Commonwealth System of Higher Education (PCSHE); Pennsylvania State University; Pennsylvania State University - University Park
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作者：RIPLEY, BD; SILVERMAN, BW
作者单位：University of Oxford
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作者：CLAYTON, DG
作者单位：University of London; University College London; Royal Free London NHS Foundation Trust; UCL Medical School
摘要：The application of Cox''s (1972) regression model for censored survival data to epidemiological studies of chronic disease incidence is discussed. A related model for association in bivariate survivorship time distributions is proposed for the analysis of familial tendency in [human] disease incidence. The possible extension of the model to general multivariate survivorship distributions is indicated.
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作者：ROBINSON, JA
摘要：Let Y(x) be the toxicity associated with some [drug] dosage level x. Let the conditional distribution of Y be normal with mean linear in x. The optimal dosage is defined to be the largest value of x such that the probability that Y(x) does not exceed .eta. is at least .gamma., where .eta. is some threshold toxicity level and .gamma. is some specified tolerance probability. Recently, Eichhorn and Zacks have introduced the problem of sequentially and consistently estimating the optimal dosage at...
