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作者：BROOKS, RJ
作者单位：University of London; University College London
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作者：KNOKE, JD
作者单位：University System of Ohio; Case Western Reserve University
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作者：WYNN, HP
作者单位：Imperial College London; University of London
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作者：MENDOZA, G; IGLEWICZ, B
作者单位：Pennsylvania Commonwealth System of Higher Education (PCSHE); Temple University
摘要：The sequential version of Colton''s decision-theoretic model for comparing 2 medical treatments was modified by considering both the patients who are in the experiment and also the patients who do not participate in the experiment, while the experiment is in progress. The consideration of the patients who do not participate in the experiment leads to major changes in the results. Both the minimax and Bayesian solutions are obtained and are compared with Colton''s equivalent results.
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作者：DIGGLE, PJ
作者单位：Newcastle University - UK
摘要：The author''s earlier analytical results on the robustness of distance-based estimators of density are supplemented by a simulation study, with particular attention being given to various types of aggregated spatial point patterns. Remarks on heterogeneous patterns are made. Finally, the results of an application to data on tree locations are described.
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作者：POCOCK, SJ
作者单位：University of Edinburgh
摘要：In clinical trials with sequential patient entry, fixed sample size designs are unjustified on ethical grounds and sequential designs are often impracticable. One solution is a group sequential design dividing patient entry into a number of equal-sized groups so that the decision to stop the trial or continue is based on repeated significance tests of the accumulated data after each group is evaluated. Exact results are obtained for a trial with 2 treatments and a normal response with known va...
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作者：AITCHISON, J
作者单位：University of Hong Kong
摘要：A statistical diagnostic system devised for a particular clinic may require appreciable modification when either the method of measurement of any of the diagnostic features changes within the clinic, or the system is applied to another clinic where different methods of measurement are used. In either circumstance, the transfer can be effectively made only on the basis of information from a calibration experiment designed to establish the relationship between the different methods of measuremen...
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作者：BUHRMAN, JM
摘要：Fisher''s (1925) test can deal with the hypothesis of equal probabilities of success of 2 experiments, A and B. The test requires a fixed number of experiments of both kinds. If the experimental design is changed into randomizing the numbers of experiments A and B, other kinds of hypotheses can be tested exactly and exact confidence intervals can be constructed.
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作者：OAKES, D
作者单位：Harvard University
摘要：Various procedures are considered for fitting a regression model to censored survival data in continuous time with time-dependent covariate functions. These include maximum likelihood with the underlying hazard function known completely and known up to a multiplicative constant and the maximization of Cox''s partial likelihood. Explicit formulae for the asymptotic variances of the estimators are derived informally and compared. It is shown how sample second derivatives may be used to estimate ...
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作者：HYDE, J
作者单位：Stanford University
摘要：In some area of life testing, subjects may enter or leave the study after they have been put on test. Statistics are presented for testing the hypothesis that the lifetimes have a given distribution for both the discrete and continuous cases. They are shown to be asymptotically normal by associating a martingale with the life process and using basic results about stopping times. There is some discussion of the effect of weight functions on power. An example of the test is provided.
