作者：Stachowicz, Izabela; Zambrano, Vilisa Moron; Giordano, Anthony J.; Ferrer-Paris, Jose R.; Kreft, Stefan
作者单位：University of Lodz; University of New South Wales Sydney
作者：Lin, Gang; Zhao, Yanan; Fu, Jingying; Jiang, Dong
作者单位：Chinese Academy of Sciences; Institute of Geographic Sciences & Natural Resources Research, CAS; Chinese Academy of Sciences; University of Chinese Academy of Sciences, CAS; Ministry of Natural Resources of the People's Republic of China
作者：Markley, Robert
作者单位：University of Illinois System; University of Illinois Urbana-Champaign
作者：Rein, Jonas; Rozema, Soren D.; Langner, Olivia C.; Zacate, Samson B.; Hardy, Melissa A.; Siu, Juno C.; Mercado, Brandon Q.; Sigman, Matthew S.; Miller, Scott J.; Lin, Song
作者单位：Cornell University; Yale University; Utah System of Higher Education; University of Utah
摘要：Catalytic enantioselective methods that are generally applicable to a broad range of substrates are rare. We report a strategy for the oxidative desymmetrization of meso-diols predicated on a nontraditional catalyst optimization protocol by using a panel of screening substrates rather than a singular model substrate. Critical to this approach was rational modulation of a peptide sequence in the catalyst incorporating a distinct aminoxyl-based active residue. A general catalyst emerged, providi...
作者：Falk, Adam F.; Espinosa, Lorelle L.
