作者：Bai, Rui; Yuan, Meng; Zhang, Pu; Luo, Ting; Shi, Yigong; Wan, Ruixue
作者单位：Westlake University; Westlake Laboratory; Westlake University; Tsinghua University
摘要：The minor spliceosome, which is responsible for the splicing of U12-type introns, comprises five small nuclear RNAs (snRNAs), of which only one is shared with the major spliceosome. In this work, we report the 3.3-angstrom cryo-electron microscopy structure of the fully assembled human minor spliceosome pre-B complex. The atomic model includes U11 small nuclear ribonucleoprotein (snRNP), U12 snRNP, and U4atac/U6atac.U5 tri-snRNP. U11 snRNA is recognized by five U11-specific proteins (20K, 25K,...
作者：Bryson, Joanna
作者单位：Hertie School
摘要：Policy that prioritizes human agency is possible, even in an age of artificial intelligence
作者：Hatton, Ian A.; Mazzarisi, Onofrio; Altieri, Ada; Smerlak, Matteo
作者单位：Max Planck Society; McGill University; University of Kansas; Abdus Salam International Centre for Theoretical Physics (ICTP); Istituto Nazionale di Oceanografia e di Geofisica Sperimentale; Centre National de la Recherche Scientifique (CNRS); Universite Paris Cite; Centre National de la Recherche Scientifique (CNRS); CNRS - Institute of Chemistry (INC); Universite PSL; Ecole Superieure de Physique et de Chimie Industrielles de la Ville de Paris (ESPCI)
摘要：The worldwide loss of species diversity brings urgency to understanding how diverse ecosystems maintain stability. Whereas early ecological ideas and classic observations suggested that stability increases with diversity, ecological theory makes the opposite prediction, leading to the long-standing diversity-stability debate. Here, we show that this puzzle can be resolved if growth scales as a sublinear power law with biomass (exponent <1), exhibiting a form of population self-regulation analo...
作者：Reardon, Sara
摘要：The mystery of infantile amnesia suggests memory works differently in the developing brain
