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作者:Brainard, Jeffrey
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作者:Yang, Wannan; Sun, Chen; Huszar, Roman; Hainmueller, Thomas; Kiselev, Kirill; Buzsaki, Gyorgy
作者单位:New York University; New York University; Mila Quebec Artificial Intelligence Institute; New York University; NYU Langone Medical Center; New York University
摘要:Experiences need to be tagged during learning for further consolidation. However, neurophysiological mechanisms that select experiences for lasting memory are not known. By combining large-scale neural recordings in mice with dimensionality reduction techniques, we observed that successive maze traversals were tracked by continuously drifting populations of neurons, providing neuronal signatures of both places visited and events encountered. When the brain state changed during reward consumpti...
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作者:Normile, Dennis
摘要:New monkey models promise insight into early stages of degenerative brain disease New monkey models promise insight into early stages of degenerative brain disease
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作者:Brainard, Jeffrey
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作者:Radhakrishnan, Adityanarayanan; Beaglehole, Daniel; Pandit, Parthe; Belkin, Mikhail
作者单位:Harvard University; Harvard University; Massachusetts Institute of Technology (MIT); Broad Institute; University of California System; University of California San Diego; Indian Institute of Technology System (IIT System); Indian Institute of Technology (IIT) - Bombay; University of California System; University of California San Diego
摘要:Understanding how neural networks learn features, or relevant patterns in data, for prediction is necessary for their reliable use in technological and scientific applications. In this work, we presented a unifying mathematical mechanism, known as average gradient outer product (AGOP), that characterized feature learning in neural networks. We provided empirical evidence that AGOP captured features learned by various neural network architectures, including transformer-based language models, co...
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作者:Wirthlin, Morgan E.; Schmid, Tobias A.; Elie, Julie E.; Zhang, Xiaomeng; Kowalczyk, Amanda; Redlich, Ruby; Shvareva, Varvara A.; Rakuljic, Ashley; Ji, Maria B.; Bhat, Ninad S.; Kaplow, Irene M.; Schaffer, Daniel E.; Lawler, Alyssa J.; Wang, Andrew Z.; Phan, BaDoi N.; Annaldasula, Siddharth; Brown, Ashley R.; Lu, Tianyu; Lim, Byung Kook; Azim, Eiman; Clark, Nathan L.; Meyer, Wynn K.; Pond, Sergei L. Kosakovsky; Chikina, Maria; Yartsev, Michael M.; Pfenning, Andreas R.
作者单位:Carnegie Mellon University; Carnegie Mellon University; University of California System; University of California Berkeley; University of California System; University of California Berkeley; University of California System; University of California Berkeley; University of California System; University of California Berkeley; Carnegie Mellon University; University of California System; University of California San Diego; Salk Institute; Pennsylvania Commonwealth System of Higher Education (PCSHE); University of Pittsburgh; Lehigh University; Pennsylvania Commonwealth System of Higher Education (PCSHE); Temple University; Pennsylvania Commonwealth System of Higher Education (PCSHE); University of Pittsburgh; Duke University; Allen Institute for Brain Science; Harvard University; Massachusetts Institute of Technology (MIT); Broad Institute
摘要:Vocal production learning (vocal learning) is a convergently evolved trait in vertebrates. To identify brain genomic elements associated with mammalian vocal learning, we integrated genomic, anatomical, and neurophysiological data from the Egyptian fruit bat (Rousettus aegyptiacus) with analyses of the genomes of 215 placental mammals. First, we identified a set of proteins evolving more slowly in vocal learners. Then, we discovered a vocal motor cortical region in the Egyptian fruit bat, an e...
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作者:Brainard, Jeffrey
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作者:Michel, Anita L.
作者单位:University of Pretoria
摘要:The age-old cattle disease has resisted rigorous control, but the BCG vaccine may do better Tuberculosis (TB) has plagued humans around the globe for thousands of years and still causes 10 million new cases every year (1). The second leading cause of death from infectious disease in humans, TB also afflicts animals, both domestic and wild. Bovine TB in cattle causes socioeconomic implications as a result of decreased production, the compulsory slaughter of infected animals, and associated soci...
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作者:Zhang, Han-Yue; Tang, Yuan-Yuan; Gu, Zhu-Xiao; Wang, Peng; Chen, Xiao-Gang; Lv, Hui-Peng; Li, Peng-Fei; Jiang, Qing; Gu, Ning; Ren, Shenqiang; Xiong, Ren-Gen
作者单位:Southeast University - China; Nanchang University; Nanjing University; Nanjing University; University System of Maryland; University of Maryland College Park
摘要:Transient implantable piezoelectric materials are desirable for biosensing, drug delivery, tissue regeneration, and antimicrobial and tumor therapy. For use in the human body, they must show flexibility, biocompatibility, and biodegradability. These requirements are challenging for conventional inorganic piezoelectric oxides and piezoelectric polymers. We discovered high piezoelectricity in a molecular crystal HOCH2(CF2)(3)CH2OH [2,2,3,3,4,4-hexafluoropentane-1,5-diol (HFPD)] with a large piez...
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作者:Handley, Margaret A.
作者单位:University of California System; University of California San Francisco