Vaccines to control tuberculosis in cattle

• 成果类型: Editorial Material
• 署名作者: Michel, Anita L.
• 署名单位: University of Pretoria
• 刊物名称: SCIENCE
• ISSN/ISSBN: 0036-12043
• DOI: 10.1126/science.ado4333
• 发表日期: 2024-03-29
• 页码: 1410-1411
• 关键词: zoonotic tuberculosis; bovine tuberculosis; mycobacterium-bovis; a call; HEALTH

摘要

The age-old cattle disease has resisted rigorous control, but the BCG vaccine may do better Tuberculosis (TB) has plagued humans around the globe for thousands of years and still causes 10 million new cases every year (1). The second leading cause of death from infectious disease in humans, TB also afflicts animals, both domestic and wild. Bovine TB in cattle causes socioeconomic implications as a result of decreased production, the compulsory slaughter of infected animals, and associated social knock-on effects (2). The BCG (Bacillus Calmette-Guerin) vaccine, which has been in use for 100 years, is currently the only vaccine available to protect children against human TB (caused by Mycobacterium tuberculosis); there is no TB vaccine for livestock (caused by the related bacterium Mycobacterium bovis). On page 1433 of this issue, Fromsa et al. (3) report field data from studies in Ethiopia that support the use of the human BCG vaccine in cattle, which could help eliminate bovine TB.