6705期

最新文章

• Natural selection drives emergent genetic homogeneity in a century-scale experiment with barley AI翻译
  作者：Landis, Jacob B.; Guercio, Angelica M.; Brown, Keely E.; Fiscus, Christopher J.; Morrell, Peter L.; Koenig, Daniel
  作者单位：University of California System; University of California Riverside; University of California System; University of California Riverside; University of Minnesota System; University of Minnesota Twin Cities
  摘要：Direct observation is central to our understanding of adaptation, but evolution is rarely documented in a large, multicellular organism for more than a few generations. In this study, we observed evolution across a century-scale competition experiment, barley composite cross II (CCII). CCII was founded in 1929 in Davis, California, with thousands of genotypes, but we found that natural selection has massively reduced genetic diversity, leading to a single lineage constituting most of the popul...
• Adaptive fungal invasion of bat cells AI翻译
  作者：Vargas-Muniz, Jose M.
  作者单位：Virginia Polytechnic Institute & State University; Marine Biological Laboratory - Woods Hole
• The Great River: The Making and Unmaking of the Mississippi AI翻译
  作者：Doyle, Martin
  作者单位：Duke University
  摘要：A rich introduction captures some but not all the remarkable river has to offer
• Rat poison's long reach AI翻译
  作者：Maron, Dina Fine
• A quantum-network register assembled with optical tweezers in an optical cavity AI翻译
  作者：Hartung, Lukas; Seubert, Matthias; Welte, Stephan; Distante, Emanuele; Rempe, Gerhard
  作者单位：Max Planck Society; Swiss Federal Institutes of Technology Domain; ETH Zurich; Barcelona Institute of Science & Technology; Universitat Politecnica de Catalunya; Institut de Ciencies Fotoniques (ICFO)
  摘要：Quantum computation and quantum communication are expected to provide users with capabilities inaccessible by classical physics. However, scalability to larger systems with many qubits is challenging. One solution is to develop a quantum network consisting of small-scale quantum registers containing computation qubits that are reversibly interfaced to communication qubits. In this study, we report on a register that uses both optical tweezers and optical lattices to deterministically assemble ...
• A crystal capping layer for formation of black-phase FAPbI3 perovskite in humid air AI翻译
  作者：Zou, Yu; Yu, Wenjin; Guo, Haoqing; Li, Qizhi; Li, Xiangdong; Li, Liang; Liu, Yueli; Wang, Hantao; Tang, Zhenyu; Yang, Shuang; Chen, Yanrun; Qu, Bo; Gao, Yunan; Chen, Zhijian; Wang, Shufeng; Zhang, Dongdong; Chen, Yihua; Chen, Qi; Zakeeruddin, Shaik M.; Peng, Yingying; Zhou, Huanping; Gong, Qihuang; Wei, Mingyang; Graetzel, Michael; Xiao, Lixin
  作者单位：Peking University; Peking University; Peking University; Tsinghua University; Beijing Institute of Technology; Swiss Federal Institutes of Technology Domain; Ecole Polytechnique Federale de Lausanne; Huairou Laboratory
  摘要：Black-phase formamidinium lead iodide (alpha-FAPbI(3)) perovskites are the desired phase for photovoltaic applications, but water can trigger formation of photoinactive impurity phases such as delta-FAPbI(3). We show that the classic solvent system for perovskite fabrication exacerbates this reproducibility challenge. The conventional coordinative solvent dimethyl sulfoxide (DMSO) promoted delta-FAPbI(3) formation under high relative humidity (RH) conditions because of its hygroscopic nature. ...
• Unmasking immune suppression AI翻译
  作者：Pitarresi, Jason R.; Fitzgerald, Katherine A.
  作者单位：University of Massachusetts System; UMass Chan Medical School; University of Massachusetts Worcester; University of Massachusetts System; University of Massachusetts Worcester; UMass Chan Medical School
• Neanderthals and moderns mingled early and often AI翻译
  作者：Gibbons, Ann
• Integrated translation and metabolism in a partially self-synthesizing biochemical network AI翻译
  作者：Giaveri, Simone; Bohra, Nitin; Diehl, Christoph; Yang, Hao Yuan; Ballinger, Martine; Paczia, Nicole; Glatter, Timo; Erb, Tobias J.
  作者单位：Max Planck Society; Max Planck Society; Max Planck Society
  摘要：One of the hallmarks of living organisms is their capacity for self-organization and regeneration, which requires a tight integration of metabolic and genetic networks. We sought to construct a linked metabolic and genetic network in vitro that shows such lifelike behavior outside of a cellular context and generates its own building blocks from nonliving matter. We integrated the metabolism of the crotonyl-CoA/ethyl-malonyl-CoA/hydroxybutyryl-CoA cycle with cell-free protein synthesis using re...
• Molecular mechanism of plasmid elimination by the DdmDE defense system AI翻译
  作者：Loeff, Luuk; Adams, David W.; Chanez, Christelle; Stutzmann, Sandrine; Righi, Laurie; Blokesch, Melanie; Jinek, Martin
  作者单位：University of Zurich; Swiss School of Public Health (SSPH+); Swiss Federal Institutes of Technology Domain; Ecole Polytechnique Federale de Lausanne
  摘要：Seventh-pandemic Vibrio cholerae strains contain two pathogenicity islands that encode the DNA defense modules DdmABC and DdmDE. In this study, we used cryogenic electron microscopy to determine the mechanistic basis for plasmid defense by DdmDE. The helicase-nuclease DdmD adopts an autoinhibited dimeric architecture. The prokaryotic Argonaute protein DdmE uses a DNA guide to target plasmid DNA. The structure of the DdmDE complex, validated by in vivo mutational studies, shows that DNA binding...