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作者：Bloomfield, Doni; Pannu, Jaspreet; Zhu, Alex W.; Ng, Madelena Y.; Lewis, Ashley; Bendavid, Eran; Asch, Steven M.; Hernandez-Boussard, Tina; Cicero, Anita; Inglesby, Tom
作者单位：Johns Hopkins University; Johns Hopkins Bloomberg School of Public Health; Fordham University; Stanford University; Stanford University; Stanford University; Stanford University
摘要：Governments should evaluate advanced models and if needed impose safety measures Great benefits to humanity will likely ensue from advances in artificial intelligence (AI) models trained on or capable of meaningfully manipulating substantial quantities of biological data, from speeding up drug and vaccine design to improving crop yields (1-3). But as with any powerful new technology, such biological models will also pose considerable risks. Because of their general-purpose nature, the same bio...
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作者：Jose, Jithu K.
作者单位：University of Hyderabad
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作者：Greenbaum, Dov
作者单位：Reichman University; Yale University
摘要：A celebrated election forecaster proposes a framework for confronting risk
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作者：Stokstad, Erik
摘要：Bluetongue spreads rapidly in sheep and cattle in six countries despite vaccination efforts
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作者：Wu, Tianyu; Luo, Yuxi; Zhang, Meiling; Chen, Biaobang; Du, Xingzhu; Gu, Hao; Xie, Siyuan; Pan, Zhiqi; Yu, Ran; Hai, Ruiqi; Niu, Xiangli; Hao, Guimin; Jin, Liping; Shi, Juanzi; Sun, Xiaoxi; Kuang, Yanping; Li, Wen; Sang, Qing; Wang, Lei
作者单位：Fudan University; Shanghai Jiao Tong University; Shanghai Jiao Tong University; Fudan University; Shanghai Academy of Science & Technology; Fudan University; Fudan University; Shanghai Jiao Tong University
摘要：Spindle bipolarization, the process of a microtubule mass transforming into a bipolar spindle, is a prerequisite for accurate chromosome segregation. In contrast to mitotic cells, the process and mechanism of spindle bipolarization in human oocytes remains unclear. Using high-resolution imaging in more than 1800 human oocytes, we revealed a typical state of multipolar intermediates that form during spindle bipolarization and elucidated the mechanism underlying this process. We found that the m...
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作者：Xu, Liuwei; Ji, Chen; Meng, Lingsen; Ampuero, Jean-Paul; Yunjun, Zhang; Mohanna, Saeed; Aoki, Yosuke
作者单位：University of California System; University of California Los Angeles; University of California System; University of California Santa Barbara; Institut de Recherche pour le Developpement (IRD); Universite Cote d'Azur; Observatoire de la Cote d'Azur; Centre National de la Recherche Scientifique (CNRS); Chinese Academy of Sciences; Aerospace Information Research Institute, CAS; Chinese Academy of Sciences; University of Chinese Academy of Sciences, CAS; University of Tokyo
摘要：To reveal the connections between the 2024 moment magnitude (M (w)) 7.5 Noto earthquake in Japan and the seismicity swarms that preceded it, we investigated its rupture process through near-source waveform analysis and source imaging techniques, combining seismic and geodetic datasets. We found notable complexity in the initial rupture stages. A strong fault asperity, which remained unbroken in preceding seismic swarms, slowed down the rupture. Then, a second rupture initiated at the opposite ...
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作者：Clarke, Ryan W.; Rognerud, Erik G.; Puente-Urbina, Allen; Barnes, David; Murdy, Paul; McGraw, Michael L.; Newkirk, Jimmy M.; Beach, Ryan; Wrubel, Jacob A.; Hamernik, Levi J.; Chism, Katherine A.; Baer, Andrea L.; Beckham, Gregg T.; Murray, Robynne E.; Rorrer, Nicholas A.
作者单位：United States Department of Energy (DOE); National Renewable Energy Laboratory - USA; United States Department of Energy (DOE); National Renewable Energy Laboratory - USA
摘要：Wind energy is helping to decarbonize the electrical grid, but wind blades are not recyclable, and current end-of-life management strategies are not sustainable. To address the material recyclability challenges in sustainable energy infrastructure, we introduce scalable biomass-derivable polyester covalent adaptable networks and corresponding fiber-reinforced composites for recyclable wind blade fabrication. Through experimental and computational studies, including vacuum-assisted resin-transf...
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作者：Keuroghlian, Alex S.; Radix, Asa E.
作者单位：Harvard University; Harvard University Medical Affiliates; Massachusetts General Hospital
摘要：Ever since the Cass Review was released in April-an evaluation by the United Kingdom's National Health Service that has led to a ban on pubertysuppressing medication for transgender and gender diverse (TGD) youth-there has been criticism of the assessment and its recommendations, and concern about how it could be leveraged to more broadly affect public health care. In response, physicians, researchers, and major medical organizations worldwide have emphasized that scientific studies point to t...
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作者：Cohen, Jon
摘要：New variants that elude immunity have caused a massive summer wave
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作者：Jean-Louis, Girardin; Seixas, Azizi A.
作者单位：University of Miami; University of Miami; University of Miami
摘要：BACKGROUND Decentralized clinical trials (DCTs) are innovative approaches to clinical research that leverage digital technologies to address the limitations of traditional site-based trials. Traditional trials often face barriers such as geographical constraints, lack of diversity among participants, and logistical challenges, limiting participant engagement and retention. These issues are particularly pronounced for historically marginalized groupings, who often experience greater obstacles i...
