作者:Wang, Quan; Wang, Tao; Cao, Lin; Mu, An; Fu, Sheng; Wang, Peipei; Gao, Yan; Ji, Wenxin; Liu, Zhenyu; Du, Zhanqiang; Guddat, Luke W.; Zhang, Wenchi; Li, Shuang; Li, Xuemei; Lou, Zhiyong; Wang, Xiangxi; Hu, Zhongyu; Rao, Zihe
作者单位:ShanghaiTech University; Chinese Academy of Sciences; Shanghai Advanced Research Institute, CAS; Tsinghua University; Nankai University; Chinese Academy of Sciences; Chinese Academy of Sciences; University of Chinese Academy of Sciences, CAS; University of Queensland; National Institute of Food & Drug Control - China
摘要:Chronic hepatitis B virus (HBV) infection poses a major global health challenge with massive morbidity and mortality. Despite a preventive vaccine, current treatments provide limited virus clearance, necessitating lifelong commitment. The HBV surface antigen (HBsAg) is crucial for diagnosis and prognosis, yet its high-resolution structure and assembly on the virus envelope remain elusive. Utilizing extensive datasets and advanced cryo-electron microscopy analysis, we present structural insight...
作者:Huetner, Johanna I.; Conti, Andrea; Kugler, David; Mittendorfer, Florian; Kresse, Georg; Schmid, Michael; Diebold, Ulrike; Balajka, Jan
作者单位:Technische Universitat Wien; University of Vienna
摘要:Macroscopic properties of materials stem from fundamental atomic-scale details, yet for insulators, resolving surface structures remains a challenge. We imaged the basal (0001) plane of alpha-aluminum oxide (alpha-Al2O3) using noncontact atomic force microscopy with an atomically defined tip apex. The surface formed a complex (root 31 x root 31)R +/- 9 degrees reconstruction. The lateral positions of the individual oxygen and aluminum surface atoms come directly from experiment; we determined ...
作者:Tannenbaum, Benn
作者单位:George Washington University
作者:He, Danfeng; Zhang, Xiaolin; Zhou, Fujiang
作者单位:Qiongtai Normal University
作者:Jupp, Andrew R.
作者单位:University of Birmingham
摘要:The structural relationship between Lewis adduct isomers is resolved
作者:O'Reilly, Meaghan A.
作者单位:University of Toronto; Sunnybrook Research Institute; Sunnybrook Health Science Center; University of Toronto
摘要:Focused ultrasound is a platform technology capable of eliciting a wide range of biological responses with high spatial precision deep within the body. Although focused ultrasound is already in clinical use for focal thermal ablation of tissue, there has been a recent growth in development and translation of ultrasound-mediated nonthermal therapies. These approaches exploit the physical forces of ultrasound to produce a range of biological responses dependent on exposure conditions. This revie...