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作者：Cho, Adrian
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作者：Sahl, Steffen J.; Matthias, Jessica; Inamdar, Kaushik; Weber, Michael; Khan, Taukeer A.; Brueser, Christian; Jakobs, Stefan; Becker, Stefan; Griesinger, Christian; Broichhagen, Johannes; Hell, Stefan W.
作者单位：Max Planck Society; University of Gottingen; UNIVERSITY GOTTINGEN HOSPITAL; University of Gottingen; Max Planck Society
摘要：Optical investigations of nanometer distances between proteins, their subunits, or other biomolecules have been the exclusive prerogative of F & ouml;rster resonance energy transfer (FRET) microscopy for decades. In this work, we show that MINFLUX fluorescence nanoscopy measures intramolecular distances down to 1 nanometer-and in planar projections down to 1 angstrom-directly, linearly, and with angstrom precision. Our method was validated by quantifying well-characterized 1- to 10-nanometer d...
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作者：Nuijten, R. J. M.; Nguyen, T.; Eikelboom, J. A. J.; Drori, O.
作者单位：Wageningen University & Research
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作者：Offord, Catherine
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作者：An, Joon-Yong; Kim, Yujin
作者单位：Korea University; Korea University; Korea University
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作者：Sanczuk, Pieter; Verheyen, Kris; Lenoir, Jonathan; Zellweger, Florian; Lembrechts, Jonas J.; Rodriguez-Sanchez, Francisco; Baeten, Lander; Bernhardt-Roemermann, Markus; De Pauw, Karen; Vangansbeke, Pieter; Perring, Michael P.; Berki, Imre; Bjorkman, Anne D.; Brunet, Joerg; Chudomelova, Marketa; De Lombaerde, Emiel; Decocq, Guillaume; Dirnbock, Thomas; Durak, Tomasz; Greiser, Caroline; Hedl, Radim; Heinken, Thilo; Jandt, Ute; Jaroszewicz, Bogdan; Kopecky, Martin; Landuyt, Dries; Macek, Martin; Malis, Frantisek; Naaf, Tobias; Nagel, Thomas A.; Petrik, Petr; Reczynska, Kamila; Schmidt, Wolfgang; Standovar, Tibor; Staude, Ingmar R.; Swierkosz, Krzysztof; Teleki, Balazs; Vanneste, Thomas; Vild, Ondrej; Waller, Donald; De Frenne, Pieter
作者单位：Ghent University; Universite de Picardie Jules Verne (UPJV); Centre National de la Recherche Scientifique (CNRS); Swiss Federal Institutes of Technology Domain; Swiss Federal Institute for Forest, Snow & Landscape Research; University of Antwerp; Utrecht University; University of Sevilla; Friedrich Schiller University of Jena; German Research Foundation (DFG); German Centre for Integrative Biodiversity Research (iDiv); UK Centre for Ecology & Hydrology (UKCEH); University of Western Australia; University of West Hungary; University of Gothenburg; University of Gothenburg; Swedish University of Agricultural Sciences; Czech Academy of Sciences; Institute of Botany of the Czech Academy of Sciences; University of Rzeszow; Stockholm University; Swedish University of Agricultural Sciences; Palacky University Olomouc; University of Potsdam; Martin Luther University Halle Wittenberg; University of Warsaw; Czech Academy of Sciences; Institute of Botany of the Czech Academy of Sciences; Czech University of Life Sciences Prague; Technical University Zvolen; National Forest Center - Slovakia; Leibniz Association; Leibniz Zentrum fur Agrarlandschaftsforschung (ZALF); University of Ljubljana; Czech University of Life Sciences Prague; University of Gottingen; Eotvos Lorand University; Leipzig University; University of Wroclaw; University of Debrecen; University of Wisconsin System; University of Wisconsin Madison
摘要：Climate change is commonly assumed to induce species' range shifts toward the poles. Yet, other environmental changes may affect the geographical distribution of species in unexpected ways. Here, we quantify multidecadal shifts in the distribution of European forest plants and link these shifts to key drivers of forest biodiversity change: climate change, atmospheric deposition (nitrogen and sulfur), and forest canopy dynamics. Surprisingly, westward distribution shifts were 2.6 times more lik...
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作者：Chajwa, Rahul; Flaum, Eliott; Bidle, Kay D.; Van Mooy, Benjamin; Prakash, Manu
作者单位：Stanford University; Stanford University; Stanford University; Stanford University; Stanford University; Rutgers University System; Rutgers University New Brunswick; Woods Hole Oceanographic Institution
摘要：Gravity-driven sinking of marine snow sequesters carbon in the ocean, constituting a key biological pump that regulates Earth's climate. A mechanistic understanding of this phenomenon is obscured by the biological richness of these aggregates and a lack of direct observation of their sedimentation physics. Utilizing a scale-free vertical tracking microscopy in a field setting, we present microhydrodynamic measurements of freshly collected marine snow aggregates from sediment traps. Our observa...
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作者：Fabreges, Dimitri; Corominas-Murtra, Bernat; Moghe, Prachiti; Kickuth, Alison; Ichikawa, Takafumi; Iwatani, Chizuru; Tsukiyama, Tomoyuki; Daniel, Nathalie; Gering, Julie; Stokkermans, Anniek; Wolny, Adrian; Kreshuk, Anna; Duranthon, Veronique; Uhlman, Virginie; Hannezo, Edouard; Hiiragi, Takashi
作者单位：Royal Netherlands Academy of Arts & Sciences; Hubrecht Institute (KNAW); European Molecular Biology Laboratory (EMBL); University of Graz; Kyoto University; Kyoto University; Shiga University of Medical Science; INRAE; Universite Paris Saclay; European Molecular Biology Laboratory (EMBL); Universite Paris Saclay; Ecole Nationale Veterinaire d'Alfort (ENVA); European Molecular Biology Laboratory (EMBL); European Bioinformatics Institute; Institute of Science & Technology - Austria; Technische Universitat Dresden; Max Planck Society; University of Zurich
摘要：How living systems achieve precision in form and function despite their intrinsic stochasticity is a fundamental yet ongoing question in biology. We generated morphomaps of preimplantation embryogenesis in mouse, rabbit, and monkey embryos, and these morphomaps revealed that although blastomere divisions desynchronized passively, 8-cell embryos converged toward robust three-dimensional shapes. Using topological analysis and genetic perturbations, we found that embryos progressively changed the...
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作者：Tsang, Chi Shing; Zheng, Xiaodong; Yang, Tong; Yan, Zhangyuan; Han, Wei; Wong, Lok Wing; Liu, Haijun; Gao, Shan; Leung, Ka Ho; Lee, Chun-Sing; Lau, Shu Ping; Yang, Ming; Zhao, Jiong; Ly, Thuc Hue
作者单位：Hong Kong Polytechnic University; City University of Hong Kong; City University of Hong Kong; Hong Kong Polytechnic University; City University of Hong Kong; City University of Hong Kong; Shenzhen Research Institute, City University of Hong Kong; Hong Kong Polytechnic University; Hong Kong Polytechnic University; Hong Kong Polytechnic University
摘要：We report the observation of an electric field in twisted-bilayer molybdenum disulfide (MoS2) and elucidate its correlation with local polar domains using four-dimensional scanning transmission electron microscopy (4D-STEM) and first-principles calculations. We reveal the emergence of in-plane topological vortices within the periodic moir & eacute; patterns for both commensurate structures at small twist angles and the incommensurate quasicrystal structure that occurs at a 30 degrees twist. Th...
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作者：Bommasani, Rishi; Kapoor, Sayash; Klyman, Kevin; Longpre, Shayne; Ramaswami, Ashwin; Zhang, Daniel; Schaake, Marietje; Ho, Daniel E.; Narayanan, Arvind; Liang, Percy
作者单位：Stanford University; Stanford University; Princeton University; Princeton University; Massachusetts Institute of Technology (MIT); Georgetown University; Stanford University; Stanford University; Stanford University; Stanford University; Stanford University; Stanford University
摘要：Foundation models (e.g., GPT-4 and Llama 3.1) are at the epicenter of artificial intelligence (AI), driving technological innovation and billions of dollars in investment. This has sparked widespread demands for regulation. Central to the debate about how to regulate foundation models is the process by which foundation models are released (1)-whether they are made available only to the model developers, fully open to the public, or somewhere in between. Open foundation models can benefit socie...
