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作者:Asare, Kwabena Boahen; Stanford, Fatima Cody
作者单位:Dartmouth College; Harvard University; Harvard Medical School
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作者:Kraft, Florian; Rodriguez-Aliaga, Piere; Yuan, Weimin; Franken, Lena; Zajt, Kamil; Hasan, Dimah; Lee, Ting-Ting; Flex, Elisabetta; Hentschel, Andreas; Innes, A. Micheil; Zheng, Bixia; Suh, Dong Sun Julia; Knopp, Cordula; Lausberg, Eva; Krause, Jeremias; Zhang, Xiaomeng; Trapane, Pamela; Carroll, Riley; Mcclatchey, Martin; Fry, Andrew E.; Wang, Lisa; Giesselmann, Sebastian; Hoang, Hieu; Baldridge, Dustin; Silverman, Gary A.; Radio, Francesca Clementina; Bertini, Enrico; Ciolfi, Andrea; Blood, Katherine A.; Agathe, Jean-Madeleine de Sainte; Charles, Perrine; Bergant, Gaber; Cuturilo, Goran; Peterlin, Borut; Diderich, Karin; Streff, Haley; Robak, Laurie; Oegema, Renske; van Binsbergen, Ellen; Herriges, John; Saunders, Carol J.; Maier, Andrea; Wolking, Stefan; Weber, Yvonne; Lochmuller, Hanns; Meyer, Stefanie; Aleman, Alberto; Polavarapu, Kiran; Nicolas, Gael; Goldenberg, Alice; Guyant, Lucie; Pope, Kathleen; Hehmeyer, Katherine N.; Monaghan, Kristin G.; Quade, Annegret; Smol, Thomas; Caumes, Roseline; Duerinckx, Sarah; Depondt, Chantal; Van Paesschen, Wim; Rieubland, Claudine; Poloni, Claudia; Guipponi, Michel; Arcioni, Severine; Meuwissen, Marije; Jansen, Anna C.; Rosenblum, Jessica; Haack, Tobias B.; Bertrand, Miriam; Gerstner, Lea; Magg, Janine; Riess, Olaf; Schulz, Joerg B.; Wagner, Norbert; Wiesmann, Martin; Weis, Joachim; Eggermann, Thomas; Begemann, Matthias; Roos, Andreas; Haeusler, Martin; Schedl, Tim; Tartaglia, Marco; Bremer, Juliane; Pak, Stephen C.; Frydman, Judith; Elbracht, Miriam; Kurth, Ingo
作者单位:RWTH Aachen University; Stanford University; Washington University (WUSTL); RWTH Aachen University; RWTH Aachen University Hospital; RWTH Aachen University; RWTH Aachen University Hospital; Dortmund University of Technology; Leibniz Association; Leibniz Institut fur Analytische Wissenschaften (ISAS); University of Calgary; University of Calgary; Nanjing Medical University; State University System of Florida; University of Florida; Cardiff University; Cardiff University; IRCCS Bambino Gesu; IRCCS Bambino Gesu; University of British Columbia; Assistance Publique Hopitaux Paris (APHP); Hopital Universitaire Pitie-Salpetriere - APHP; Sorbonne Universite; Sorbonne Universite; University Medical Centre Ljubljana; University of Belgrade; University of Belgrade; Erasmus University Rotterdam; Erasmus MC; Baylor College of Medicine; Utrecht University; Utrecht University Medical Center; Children's Mercy Hospital; University of Missouri System; University of Missouri Kansas City; RWTH Aachen University; RWTH Aachen University Hospital; RWTH Aachen University; RWTH Aachen University Hospital; RWTH Aachen University; University of Ottawa; Ottawa Hospital Research Institute; Children's Hospital of Eastern Ontario; University of Ottawa; National Institute of Mental Health & Neurosciences - India; Institut National de la Sante et de la Recherche Medicale (Inserm); Universite de Rouen Normandie; Universite de Rouen Normandie; CHU de Rouen; State University System of Florida; University of South Florida; RWTH Aachen University; RWTH Aachen University Hospital; Universite de Lille; CHU Lille; Universite Libre de Bruxelles; Universite Libre de Bruxelles; KU Leuven; KU Leuven; University Hospital Leuven; University of Geneva; University of Geneva; University of Antwerp; University of Antwerp; Eberhard Karls University of Tubingen; Eberhard Karls University of Tubingen; TUBINGEN UNIVERSITY CHILDRENS HOSPITAL; RWTH Aachen University; RWTH Aachen University Hospital; University of Duisburg Essen; Heinrich Heine University Dusseldorf; Heinrich Heine University Dusseldorf Hospital; Washington University (WUSTL)
摘要:Malformations of the brain are common and vary in severity, from negligible to potentially fatal. Their causes have not been fully elucidated. Here, we report pathogenic variants in the core protein-folding machinery TRiC/CCT in individuals with brain malformations, intellectual disability, and seizures. The chaperonin TRiC is an obligate hetero-oligomer, and we identify variants in seven of its eight subunits, all of which impair function or assembly through different mechanisms. Transcriptom...
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作者:Li, Ziqiang P.; Moreau, Hortense; Petit, Jules D.; Moraes, Tatiana S.; Smokvarska, Marija; Perez-Sancho, Jessica; Petrel, Melina; Decoeur, Fanny; Brocard, Lysiane; Chambaud, Clement; Grison, Magali S.; Paterlini, Andrea; Glavier, Marie; Hoornaert, Lucie; Joshi, Amit S.; Gontier, Etienne; Prinz, William A.; Jaillais, Yvon; Taly, Antoine; Campelo, Felix; Caillaud, Marie-Cecile; Bayer, Emmanuelle M.
作者单位:Centre National de la Recherche Scientifique (CNRS); CNRS - National Institute for Biology (INSB); Universite de Bordeaux; Universite de Bordeaux; Centre National de la Recherche Scientifique (CNRS); Institut National de la Sante et de la Recherche Medicale (Inserm); INRAE; University of Tennessee System; University of Tennessee Knoxville; University of Texas System; University of Texas Dallas; University of Texas Southwestern Medical Center; Centre National de la Recherche Scientifique (CNRS); Ecole Normale Superieure de Lyon (ENS de LYON); Universite Claude Bernard Lyon 1; INRAE; Centre National de la Recherche Scientifique (CNRS); CNRS - Institute of Chemistry (INC); Universite Paris Cite; Barcelona Institute of Science & Technology; Universitat Politecnica de Catalunya; Institut de Ciencies Fotoniques (ICFO); University of Edinburgh
摘要:Diverging from conventional cell division models, plant cells undergo incomplete division to generate plasmodesmata communication bridges between daughter cells. Although fundamental for plant multicellularity, the molecular events leading to bridge stabilization, as opposed to severing, remain unknown. Using electron tomography, we mapped the transition from cell plate fenestrae to plasmodesmata. We show that the endoplasmic reticulum (ER) connects daughter cells across fenestrae, and as the ...
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作者:Brainard, Jeffrey
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作者:Mariani, Michela; Wills, Alastair; Herbert, Annika; Adeleye, Matthew; Florin, S. Anna; Cadd, Haidee; Connor, Simon; Kershaw, Peter; Theuerkauf, Martin; Stevenson, Janelle; Fletcher, Michael-Shawn; Mooney, Scott; Bowman, David; Haberle, Simon
作者单位:University of Nottingham; Australian National University; Australian National University; Australian National University; University of Cambridge; Australian National University; University of Wollongong; University of Wollongong; Monash University; Universitat Greifswald; Leuphana University Luneburg; University of Melbourne; University of Melbourne; University of Melbourne; University of New South Wales Sydney; University of Tasmania
摘要:Wildfires in forests globally have become more frequent and intense because of changes in climate and human management. Shrub layer fuels allow fire to spread vertically to forest canopy, creating high-intensity fires. Our research provides a deep-time perspective on shrub fuel loads in fire-prone southeastern Australia. Comparing 2833 records for vegetation cover, past climate, biomass burning, and human population size across different phases of human occupation, we demonstrated that Indigen...
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作者:Mcdermott, Luca; Walters, Zach G.; French, Sarah A.; Clark, Allison M.; Ding, Jiaming; Kelleghan, Andrew V.; Houk, K. N.; Garg, Neil K.
作者单位:University of California System; University of California Los Angeles
摘要:The pi-bonds in unsaturated organic molecules are typically associated with having well-defined geometries that are conserved across diverse structural contexts. Nonetheless, these geometries can be distorted, leading to heightened reactivity of the pi-bond. Although pi-bond-containing compounds with bent geometries are well utilized in synthetic chemistry, the corresponding leveraging of pi-bond-containing compounds that display twisting or pyramidalization remains underdeveloped. We report a...
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作者:Schwarzer, Michael; Borodin, Dmitriy; Wang, Yingqi; Fingerhut, Jan; Kitsopoulos, Theofanis N.; Auerbach, Daniel J.; Guo, Hua; Wodtke, Alec M.
作者单位:University of Gottingen; University of New Mexico; University of Southern Mississippi
摘要:Atomic-scale structures that account for the acceleration of reactivity by heterogeneous catalysts often form only under reaction conditions of high temperatures and pressures, making them impossible to observe with low-temperature, ultra-high-vacuum methods. We present velocity-resolved kinetics measurements for catalytic hydrogen oxidation on palladium over a wide range of surface concentrations and at high temperatures. The rates exhibit a complex dependence on oxygen coverage and step dens...
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作者:Yaqub, Muneer
作者单位:University of Texas System; University of Texas Dallas
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作者:Brainard, Jeffrey
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作者:Ding, Yong; Ding, Bin; Shi, Pengju; Romano-deGea, Jan; Li, Yahui; Turnell-Ritson, Roland C.; Syzgantseva, Olga A.; Yavuz, Ilhan; Xia, Ming; Yu, Ruohan; Syzgantseva, Maria A.; Audinot, Jean-Nicolas; Miao, Xiaohe; Liao, Xiaobin; Li, Jiantao; Doerflinger, Patrick; Dyakonov, Vladimir; Liu, Cheng; Yang, Yi; Tao, Li; Brooks, Keith G.; Slonopas, Andre; Pan, Jiahong; Zhang, Lei; An, Qinyou; Rong, Yaoguang; Peng, Jun; Ding, Liming; Shi, Enzheng; Mai, Liqiang; Dai, Songyuan; Zhao, Kangning; Sheng, Jiang; Wang, Rui; Dyson, Paul J.; Nazeeruddin, Mohammad Khaja
作者单位:North China Electric Power University; Swiss Federal Institutes of Technology Domain; Ecole Polytechnique Federale de Lausanne; Soochow University - China; Westlake University; Lomonosov Moscow State University; Marmara University; Wuhan University of Technology; Mendeleev University of Chemical Technology of Russia; Luxembourg Institute of Science & Technology; United States Department of Energy (DOE); Argonne National Laboratory; University of Wurzburg; Hubei University; Johns Hopkins University; Guangxi University; Chinese Academy of Sciences; National Center for Nanoscience & Technology, CAS; Changzhou Institute of Technology
摘要:Perovskite solar modules (PSMs) show outstanding power conversion efficiencies (PCEs), but long-term operational stability remains problematic. We show that incorporating N,N-dimethylmethyleneiminium chloride into the perovskite precursor solution formed dimethylammonium cation and that previously unobserved methyl tetrahydrotriazinium ([MTTZ](+)) cation effectively improved perovskite film. The in situ formation of [MTTZ](+) cation increased the formation energy of iodine vacancies and enhanc...