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作者：Sigsgaard, Torben; Hoffmann, Barbara
作者单位：Aarhus University; Aarhus University; Heinrich Heine University Dusseldorf
摘要：A broader approach to assessing the burden of disease from air pollution is required
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作者：Servick, Kelly
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作者：Curry, Andrew
摘要：Complex tools from 300,000-year-old deposit at Schoningen in Germany point to a wood age
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作者：[Anonymous]
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作者：Thongchol, Jirapat; Yu, Zihao; Harb, Laith; Lin, Yiruo; Koch, Matthias; Theodore, Matthew; Narsaria, Utkarsh; Shaevitz, Joshua; Gitai, Zemer; Wu, Yinghao; Zhang, Junjie; Zeng, Lanying
作者单位：Texas A&M University System; Texas A&M University College Station; Texas A&M University System; Texas A&M University College Station; Texas A&M University System; Texas A&M University College Station; Princeton University; Princeton University; Princeton University; Texas A&M University System; Texas A&M University College Station; Montefiore Medical Center; Albert Einstein College of Medicine; Yeshiva University
摘要：The retractile type IV pilus (T4P) is important for virulence of the opportunistic human pathogen Pseudomonas aeruginosa. The single-stranded RNA (ssRNA) phage PP7 binds to T4P and is brought to the cell surface through pilus retraction. Using fluorescence microscopy, we discovered that PP7 detaches T4P, which impairs cell motility and restricts the pathogen's virulence. Using cryo-electron microscopy, mutagenesis, optical trapping, and Langevin dynamics simulation, we resolved the structure o...
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作者：Drazen, Jeffrey M.; Fredberg, Jeffrey J.
作者单位：Harvard University; Harvard T.H. Chan School of Public Health
摘要：Bronchoconstriction causes epithelial cell extrusion that promotes airway inflammation
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作者：Pennisi, Elizabeth
摘要：London's Natural History Museum gets nearly $200 million to scan country's collections
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作者：Choi, Hwa Seob; Lin, Jun; Wang, Gang; Wong, Walter P. D.; Park, In-Hyeok; Lin, Fang; Yin, Jun; Leng, Kai; Lin, Junhao; Loh, Kian Ping
作者单位：Hong Kong Polytechnic University; Southern University of Science & Technology; National University of Singapore; Chungnam National University; South China Agricultural University; Hong Kong Polytechnic University
摘要：Recently, the emergence of all-organic perovskites with three-dimensional (3D) structures has expanded the potential applications of perovskite materials. However, the synthesis and utilization of all-organic perovskites in 2D form remain largely unexplored because the design principle has not been developed. We present the successful synthesis of a metal-free 2D layered perovskite, denoted as the Choi-Loh van der Waals phase (CL-v phase), with the chemical formula A2B2X4, where A represents a...
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作者：Uppalapati, Siva; Kant, Sashi; Liu, Lin; Kim, Ju-Sim; Orlicky, David; Mcclelland, Michael; Vazquez-Torres, Andres
作者单位：University of Colorado System; University of Colorado Anschutz Medical Campus; University of Colorado System; University of Colorado Anschutz Medical Campus; University of California System; University of California Irvine
摘要：Phage viruses shape the evolution and virulence of their bacterial hosts. The Salmonella enterica genome encodes several stress-inducible prophages. The Gifsy-1 prophage terminase protein, whose canonical function is to process phage DNA for packaging in the virus head, unexpectedly acts as a transfer ribonuclease (tRNase) under oxidative stress, cleaving the anticodon loop of tRNALeu. The ensuing RNA fragmentation compromises bacterial translation, intracellular survival, and recovery from ox...
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作者：Ye Qian; Gao Yuzhou; Patel, Rishi Jai; Cao Bo; Li Aikang; Powell, Jackson; Cai Yifei; Marin-Beltran, Isabel; Tao Zecheng; Ejaz, Maryam; Zaidi, Syed S.; Gupta, Ankita; See, Ming She; Cao, Xiangkun Elvis; Fulco, Ginevra; Lei Chaoyu; Han Sutao; Teng Dequn; Bezerra, Paulo; Xia Yuanxing; Montesdeoca Molina, Becky Raquel; Zhang Tianwei; Heim, Ashley Barbara; Uzonyi, Anna
作者单位：Anhui Medical University; University of Pennsylvania; Xi'an Jiaotong University; Shantou University; Shanghai Jiao Tong University; Universite de Bordeaux; INRAE; Banaras Hindu University (BHU); Universiti Malaysia Terengganu; Massachusetts Institute of Technology (MIT); Shanghai Jiao Tong University; Ghent University; University of Cambridge; Universidade Federal Rural do Semi-Arido (UFERSA); Hohai University; Southwest University - China; Cornell University; Weizmann Institute of Science
