6730期

最新文章

• Prize-winning image showcases protein diversity AI翻译
  作者：Brainard, Jeffrey
• High-latitude eruption drove chill AI翻译
  作者：Brainard, Jeffrey
• Neuroethology of natural actions in freely moving monkeys AI翻译
  作者：Lanzarini, Francesca; Maranesi, Monica; Rondoni, Elena Hilary; Albertini, Davide; Ferretti, Elena; Lanzilotto, Marco; Micera, Silvestro; Mazzoni, Alberto; Bonini, Luca
  作者单位：University of Parma; Scuola Superiore Sant'Anna; Scuola Superiore Sant'Anna; Scuola Superiore Sant'Anna; Vita-Salute San Raffaele University; Scuola Superiore Sant'Anna; Swiss Federal Institutes of Technology Domain; Ecole Polytechnique Federale de Lausanne
  摘要：The current understanding of primate natural action organization derives from laboratory experiments in restrained contexts (RCs) under the assumption that this knowledge generalizes to freely moving contexts (FMCs). In this work, we developed a neurobehavioral platform to enable wireless recording of the same premotor neurons in both RCs and FMCs. Neurons often encoded the same hand and mouth actions differently in RCs and FMCs. Furthermore, in FMCs, we identified cells that selectively encod...
• Impacts of EPA's finalized power plant greenhouse gas standards AI翻译
  作者：Bistline, John; Bergman, Aaron; Blanford, Geoffrey; Brown, Maxwell; Burtraw, Dallas; Domeshek, Maya; Fawcett, Allen; Hamilton, Anne; Iyer, Gokul; Jenkins, Jesse; King, Ben; Kolus, Hannah; Levin, Amanda; Luo, Qian; Rennert, Kevin; Robertson, Molly; Roy, Nicholas; Russell, Ethan; Shawhan, Daniel; Steinberg, Daniel; van Brummen, Anna; Van Horn, Grace; Venkatesh, Aranya; Weyant, John; Wiser, Ryan; Zhao, Alicia
  作者单位：Electric Power Research Institute (EPRI); Resources for the Future; Colorado School of Mines; University System of Maryland; University of Maryland College Park; United States Department of Energy (DOE); National Renewable Energy Laboratory - USA; Princeton University; Stanford University; United States Department of Energy (DOE); Lawrence Berkeley National Laboratory
  摘要：Emissions reductions may be met with relatively small costs
• NIH sets out to double check biomedical studies AI翻译
  作者：Kaiser, Jocelyn
  摘要：But so far, few investigators seem interested in having their work repeated
• Bile acid synthesis impedes tumor-specific T cell responses during liver cancer AI翻译
  作者：Varanasi, Siva Karthik; Chen, Dan; Liu, Yingluo; Johnson, Melissa A.; Miller, Cayla M.; Ganguly, Souradipta; Lande, Kathryn; LaPorta, Michael A.; Hoffmann, Filipe Araujo; Mann, Thomas H.; Teneche, Marcos G.; Casillas, Eduardo; Mangalhara, Kailash C.; Mathew, Varsha; Sun, Ming; Jensen, Isaac J.; Farsakoglu, Yagmur; Chen, Timothy; Parisi, Bianca; Deota, Shaunak; Havas, Aaron; Lee, Jin; Chung, H. Kay; Schietinger, Andrea; Panda, Satchidananda; Williams, April E.; Farber, Donna L.; Dhar, Debanjan; Adams, Peter D.; Feng, Gen-Sheng; Shadel, Gerald S.; Sundrud, Mark S.; Kaech, Susan M.
  作者单位：Salk Institute; University of California System; University of California San Diego; Sanford Burnham Prebys Medical Discovery Institute; University of California System; University of California San Diego; Salk Institute; Columbia University; NewYork-Presbyterian Hospital; Columbia University; NewYork-Presbyterian Hospital; Salk Institute; Memorial Sloan Kettering Cancer Center; Cornell University; Dartmouth College; Dartmouth College; University of Massachusetts System; University of Massachusetts Worcester
  摘要：The metabolic landscape of cancer greatly influences antitumor immunity, yet it remains unclear how organ-specific metabolites in the tumor microenvironment influence immunosurveillance. We found that accumulation of primary conjugated and secondary bile acids (BAs) are metabolic features of human hepatocellular carcinoma and experimental liver cancer models. Inhibiting conjugated BA synthesis in hepatocytes through deletion of the BA-conjugating enzyme bile acid-CoA:amino acid N-acyltransfera...
• Fish could personalize cancer treatments AI翻译
  作者：Leslie, Mitch
  摘要：The first clinical trial of zebrafish embryos acting as cancer avatars will start soon
• Tropical forest clearance impacts biodiversity and function, whereas logging changes structure AI翻译
  作者：Marsh, Charles J.; Turner, Edgar C.; Blonder, Benjamin Wong; Bongalov, Boris; Both, Sabine; Cruz, Rudi S.; Elias, Dafydd M. O.; Hemprich-Bennett, David; Jotan, Palasiah; Kemp, Victoria; Kritzler, Ully H.; Milne, Sol; Milodowski, David T.; Mitchell, Simon L.; Pillco, Milenka Montoya; Nunes, Matheus Henrique; Riutta, Terhi; Robinson, Samuel J. B.; Slade, Eleanor M.; Bernard, Henry; Burslem, David F. R. P.; Chung, Arthur Y. C.; Clare, Elizabeth L.; Coomes, David A.; Davies, Zoe G.; Edwards, David P.; Johnson, David; Kratina, Pavel; Malhi, Yadvinder; Majalap, Noreen; Nilus, Reuben; Ostle, Nicholas J.; Rossiter, Stephen J.; Struebig, Matthew J.; Tobias, Joseph A.; Williams, Mathew; Ewers, Robert M.; Lewis, Owen T.; Reynolds, Glen; Teh, Yit Arn; Hector, Andy
  作者单位：University of Oxford; University of Cambridge; University of California System; University of California Berkeley; University of Cambridge; University of New England; University of Aberdeen; Universidad Nacional de San Antonio Abad del Cusco; Lancaster University; UK Centre for Ecology & Hydrology (UKCEH); University of London; Queen Mary University London; Czech University of Life Sciences Prague; University of Manchester; University of Edinburgh; University of Edinburgh; University of Kent; University of Aberdeen; University System of Maryland; University of Maryland College Park; University of Oxford; University of Oxford; UK Centre for Ecology & Hydrology (UKCEH); Imperial College London; Lancaster University; Nanyang Technological University; Universiti Malaysia Sabah; Pusat Penyelidikan Hutan; York University - Canada; University of Cambridge; Newcastle University - UK; University of Oxford; University of Oxford; National University of Singapore
  摘要：The impacts of degradation and deforestation on tropical forests are poorly understood, particularly at landscape scales. We present an extensive ecosystem analysis of the impacts of logging and conversion of tropical forest to oil palm from a large-scale study in Borneo, synthesizing responses from 82 variables categorized into four ecological levels spanning a broad suite of ecosystem properties: (i) structure and environment, (ii) species traits, (iii) biodiversity, and (iv) ecosystem funct...
• Building materials could store more than 16 billion tonnes of CO2 annually AI翻译
  作者：Van Roijen, Elisabeth; Miller, Sabbie A.; Davis, Steven J.
  作者单位：University of California System; University of California Davis; Stanford University
  摘要：Achieving net-zero greenhouse gas emissions likely entails not only lowering emissions but also deploying carbon dioxide (CO2) removal technologies. We explored the annual potential to store CO2 in building materials. We found that fully replacing conventional building materials with CO2-storing alternatives in new infrastructure could store as much as 16.6 +/- 2.8 billion tonnes of CO2 each year-roughly 50% of anthropogenic CO2 emissions in 2021. The total storage potential is far more sensit...
• Losing ground AI翻译
  作者：Cornwall, Warren
  摘要：Starved of sediment and losing protective reeds, the Mississippi River's sprawling delta could soon vanish