6747期

最新文章

• Spontaneous formation of robust two-dimensional perovskite phases AI翻译
  作者：Tan, Shaun; Shih, Meng-Chen; Lu, Yongli; Choi, Seung-Gu; Dong, Yifan; Lee, Joo-Hong; Yavuz, Ilhan; Larson, Bryon W.; Park, So Yeon; Kodalle, Tim; Zhang, Ruiqi; Grotevent, Matthias J.; Lin, Yu-Kuan; Zhu, Hua; Bulovic, Vladimir; Sutter-Fella, Carolin M.; Park, Nam-Gyu; Beard, Matthew C.; Lee, Jin-Wook; Zhu, Kai; Bawendi, Moungi G.
  作者单位：Sungkyunkwan University (SKKU); Sungkyunkwan University (SKKU); United States Department of Energy (DOE); National Renewable Energy Laboratory - USA; Marmara University; United States Department of Energy (DOE); Lawrence Berkeley National Laboratory; United States Department of Energy (DOE); Lawrence Berkeley National Laboratory; Massachusetts Institute of Technology (MIT); Sungkyunkwan University (SKKU); Sungkyunkwan University (SKKU)
  摘要：The two-dimensional on three-dimensional (2D/3D) perovskite bilayer heterostructure can improve the stability and performance of perovskite solar cells. We show that the 2D/3D perovskite stack in a device evolves dynamically during its end-of-life decomposition. Initially phase-pure 2D interlayers can evolve differently, resulting in different device stabilities. We show that a robust 2D interlayer can be formed using mixed solvents to regulate its crystallinity and phase purity. The resulting...
• Moving past the detractors AI翻译
  作者：Chaplin, Lan Nguyen
  作者单位：Northwestern University
• Sedentary chromosomal integrons as biobanks of bacterial antiphage defense systems AI翻译
  作者：Darracq, Baptiste; Littner, Eloi; Brunie, Manon; Bos, Julia; Kaminski, Pierre Alexandre; Depardieu, Florence; Slesak, Weronika; Debatisse, Kevin; Touchon, Marie; Bernheim, Aude; Bikard, David; Le Roux, Frederique; Mazel, Didier; Rocha, Eduardo P. C.; Loot, Celine
  作者单位：Pasteur Network; Universite Paris Cite; Institut Pasteur Paris; Centre National de la Recherche Scientifique (CNRS); CNRS - National Institute for Biology (INSB); Sorbonne Universite; Centre National de la Recherche Scientifique (CNRS); CNRS - National Institute for Biology (INSB); Pasteur Network; Universite Paris Cite; Institut Pasteur Paris; Pasteur Network; Universite Paris Cite; Institut Pasteur Paris; Centre National de la Recherche Scientifique (CNRS); CNRS - National Institute for Biology (INSB); Pasteur Network; Universite Paris Cite; Institut Pasteur Paris; Centre National de la Recherche Scientifique (CNRS); CNRS - National Institute for Biology (INSB); Universite de Montreal
  摘要：Integrons are genetic systems that drive bacterial adaptation by acquiring, expressing, and shuffling gene cassettes. While mobile integrons are well known for spreading antibiotic resistance genes, the functions of the hundreds of cassettes carried by sedentary integrons remain largely unexplored. We show that many of these cassettes encode small variants of known antiphage systems that favor their inclusion in the integron. We also demonstrate that nearly 10% of the integron cassettes in the...
• The hunt for common tumor antigens AI翻译
  作者：Tuveson, David A.
  作者单位：Cold Spring Harbor Laboratory
• NIH dismantles training pipeline for Deaf researchers AI翻译
  作者：Jacobs, Phie
• Mobile integrons encode phage defense systems AI翻译
  作者：Kieffer, Nicolas; Hipolito, Alberto; Ortiz-Miravalles, Laura; Blanco, Paula; Delobelle, Thomas; Vizuete, Patricia; Ojeda, Francisco Manuel; Jove, Thomas; Jurenas, Dukas; Garcia-Quintanilla, Meritxell; Carvalho, Andre; Domingo-Calap, Pilar; Escudero, Jose Antonio
  作者单位：Complutense University of Madrid; Complutense University of Madrid; CHU Limoges; Universite de Limoges; Institut National de la Sante et de la Recherche Medicale (Inserm); Fundacion Jimenez Diaz; Instituto de Salud Carlos III; Consejo Superior de Investigaciones Cientificas (CSIC); Institut National de la Sante et de la Recherche Medicale (Inserm)
  摘要：Integrons are bacterial genetic elements that capture, stockpile, and modulate the expression of genes encoded in integron cassettes. Mobile integrons (MIs) are borne on plasmids, acting as a vehicle for hundreds of antimicrobial resistance genes among key pathogens. These elements also carry gene cassettes of unknown function (gcus) whose role and adaptive value remain unexplored. In this work, we show that gcus encode phage resistance systems, many of which are newly discovered. Bacteriophag...
• Trump slashes studies of online lies-and how to counter them AI翻译
  作者：Kupferschmidt, Kai
• Science's enduring role in climate policy AI翻译
  作者：Yang, Y. Tony
  作者单位：George Washington University
• De novo design of porphyrin-containing proteins as efficient and stereoselective catalysts AI翻译
  作者：Hou, Kaipeng; Huang, Wei; Qi, Miao; Tugwell, Thomas H.; Alturaifi, Turki M.; Chen, Yuda; Zhang, Xingjie; Lu, Lei; Mann, Samuel I.; Liu, Peng; Yang, Yang; DeGrado, William F.
  作者单位：University of California System; University of California San Francisco; University of California System; University of California San Francisco; University of California System; University of California Santa Barbara; Pennsylvania Commonwealth System of Higher Education (PCSHE); University of Pittsburgh; University of California System; University of California Riverside; University of California System; University of California Santa Barbara
  摘要：De novo design of protein catalysts with high efficiency and stereoselectivity provides an attractive approach toward the design of environmentally benign catalysts. Here, we design proteins that incorporate histidine-ligated synthetic porphyrin and heme ligands. Four of 10 designed proteins catalyzed cyclopropanation with an enantiomeric ratio greater than 99:1. A second class of proteins were designed to catalyze a silicon-hydrogen insertion and were optimized by directed evolution in whole ...
• How Trump upended science AI翻译
  作者：Malakoff, David