作者：Alig, Stefan K.; Shahrokh Esfahani, Mohammad; Garofalo, Andrea; Li, Michael Yu; Rossi, Cedric; Flerlage, Tim; Flerlage, Jamie E.; Adams, Ragini; Binkley, Michael S.; Shukla, Navika; Jin, Michael C.; Olsen, Mari; Telenius, Adele; Mutter, Jurik A.; Schroers-Martin, Joseph G.; Sworder, Brian J.; Rai, Shinya; King, Daniel A.; Schultz, Andre; Bogeholz, Jan; Su, Shengqin; Kathuria, Karan R.; Liu, Chih Long; Kang, Xiaoman; Strohband, Maya J.; Langfitt, Deanna; Pobre-Piza, Kristine Faye; Surman, Sherri; Tian, Feng; Spina, Valeria; Tousseyn, Thomas; Buedts, Lieselot; Hoppe, Richard; Natkunam, Yasodha; Fornecker, Luc-Matthieu; Castellino, Sharon M.; Advani, Ranjana; Rossi, Davide; Lynch, Ryan; Ghesquieres, Herve; Casasnovas, Olivier; Kurtz, David M.; Marks, Lianna J.; Link, Michael P.; Andre, Marc; Vandenberghe, Peter; Steidl, Christian; Diehn, Maximilian; Alizadeh, Ash A.
作者单位：Stanford University; Universite Bourgogne Europe; CHU Dijon Bourgogne; Institut National de la Sante et de la Recherche Medicale (Inserm); Universite Bourgogne Europe; Institut Agro; AgroSup Dijon; St Jude Children's Research Hospital; St Jude Children's Research Hospital; Stanford University; Stanford University; St Jude Children's Research Hospital; KU Leuven; KU Leuven; Stanford University; Institut National de la Sante et de la Recherche Medicale (Inserm); Universites de Strasbourg Etablissements Associes; Universite de Strasbourg; Emory University; Children's Healthcare of Atlanta (CHOA); Institute of Oncology Research (IOR); Universita della Svizzera Italiana; Fred Hutchinson Cancer Center; CHU Lyon; Universite Catholique Louvain; KU Leuven; University Hospital Leuven
摘要：The scarcity of malignant Hodgkin and Reed-Sternberg cells hampers tissue-based comprehensive genomic profiling of classic Hodgkin lymphoma (cHL). By contrast, liquid biopsies show promise for molecular profiling of cHL due to relatively high circulating tumour DNA (ctDNA) levels1-4. Here we show that the plasma representation of mutations exceeds the bulk tumour representation in most cases, making cHL particularly amenable to noninvasive profiling. Leveraging single-cell transcriptional prof...
作者：Ledmyr, Helena; Abrams, Mathew; McIntosh, Randy
作者单位：Simon Fraser University
作者：Choras, Michal; Pawlicki, Marek; Kozik, Rafal; Pawlicka, Aleksandra
作者单位：Bydgoszcz University of Science & Technology; University of Warsaw
作者：Brodie, Jedediah F.; Mohd-Azlan, Jayasilan; Chen, Cheng; Wearn, Oliver R.; Deith, Mairin C. M.; Ball, James G. C.; Slade, Eleanor M.; Burslem, David F. R. P.; Teoh, Shu Woan; Williams, Peter J.; Nguyen, An; Moore, Jonathan H.; Goetz, Scott J.; Burns, Patrick; Jantz, Patrick; Hakkenberg, Christopher R.; Kaszta, Zaneta M.; Cushman, Sam; Coomes, David; Helmy, Olga E.; Reynolds, Glen; Rodriguez, Jon Paul; Jetz, Walter; Luskin, Matthew Scott
作者：Pahil, Karanbir S.; Gilman, Morgan S. A.; Baidin, Vadim; Clairfeuille, Thomas; Mattei, Patrizio; Bieniossek, Christoph; Dey, Fabian; Muri, Dieter; Baettig, Remo; Lobritz, Michael; Bradley, Kenneth; Kruse, Andrew C.; Kahne, Daniel
