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作者:Bogdanov, Georgii; Strzelecka, Aleksandra Anna; Kaimal, Nikhil; Senft, Stephen L.; Lee, Sanghoon; Hanlon, Roger T.; Gorodetsky, Alon A.
作者单位:University of California System; University of California Irvine; Marine Biological Laboratory - Woods Hole; University of California System; University of California Irvine
摘要:The manipulation of light by means of materials with varying refractive index distributions is widespread among natural systems and modern technologies. However, understanding how animals leverage refractive index differences for dynamic color changes and then translating such insight into tunable optical devices remains challenging. We experimentally and computationally demonstrated that iridescent cells (iridophores) containing Bragg reflectors with sinusoidal-wave (rugate) refractive index ...
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作者:Moya, Ivan M.
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作者:Yin, Xiaobo
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作者:Mervis, Jeffrey
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作者:Mohajer, Mercede Azizbaig; Basuri, Pallab; Evdokimov, Andrei; David, Gregory; Zindel, Daniel; Miliordos, Evangelos; Signorell, Ruth
作者单位:Swiss Federal Institutes of Technology Domain; ETH Zurich; Auburn University System; Auburn University
摘要:Urea is a key molecule in the search for the origin of life and a basic chemical produced in large quantities by industry. Its formation from ammonia and carbon dioxide requires either high pressures and temperatures or, under milder conditions, catalysts or additional reagents. In this study, we observed the spontaneous formation of urea under ambient conditions from ammonia and carbon dioxide in the surface layer of aqueous droplets. Single, optically trapped droplets were probed by using Ra...
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作者:Nelson, Alondra
作者单位:Institute for Advanced Study - USA
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作者:Ozawa, Shinzaburo; Munekane, Hiroshi; Suito, Hisashi; Yarai, Hiroshi
摘要:Using Global Navigation Satellite System data, we investigated the interplate slip before, during, and after the 2024 Hyuga-nada earthquake in Japan. Before the earthquake, a moment magnitude (Mw) 6.0 slow-slip event (SSE) was observed from late 2023 in a downdip extension of the mainshock. The coseismic slip was adjacent to the 1996 Hyuga-nada earthquake source. The afterslip resolved near the hypocenter area and in the downdip extension of the mainshock, reaching Mw 6.7 on 16 September 2024....
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作者:Ma, Wei Jen; Wang, Changqing; Kothandapani, Jagatheeswaran; Luzentales-Simpson, Matthew; Menzies, Susan C.; Bescucci, Danisa M.; Lange, Maximo E.; Fraser, Alexander S. C.; Gusse, Jenny F.; House, Kathaleen E.; Moote, Paul E.; Xing, Xiaohui; Grondin, Julie M.; Hui, Benjamin Wei-Qiang; Clarke, Sandra T.; Shelton, Tara G.; Haskey, Natasha; Gibson, Deanna L.; Martens, Eric C.; Abbott, D. Wade; Inglis, G. Douglas; Sly, Laura M.; Brumer, Harry
作者单位:University of British Columbia; University of British Columbia; BC Children's Hospital; University of British Columbia; University of British Columbia; Agriculture & Agri Food Canada; University of British Columbia; University of British Columbia Okanagan; University of Michigan System; University of Michigan
摘要:The gut microbiota of mammals possess distinctive metabolic pathways with untapped therapeutic potential. Using molecular insights into dietary fiber metabolism by the human gut microbiota, we designed a targeted drug delivery system, called GlycoCaging, that is based on bespoke glycoconjugates of a complex plant oligosaccharide. GlycoCaging of exemplar anti-inflammatory drugs enabled release of active molecules triggered by specific glycosidases of autochthonous gut bacteria. GlycoCaging ensu...
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作者:Edgington, Joshua R.; Saffer, Demian M.; Williams, Charles A.
作者单位:University of Texas System; University of Texas Austin; GNS Science - New Zealand
摘要:Patterns of strain accumulation and release offshore in subduction zones are directly linked to the potential for shallow coseismic slip and tsunamigenesis, but these patterns remain elusive. In this work, we analyze formation pore pressure records from three offshore borehole observatories at the Nankai subduction zone, Honshu, Japan, to capture detailed slip-time histories of two slow slip events (SSEs) along the outermost reaches of the plate boundary. Slip initiates similar to 30 kilometer...
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作者:Zhang, Zining; Dong, Guangbin
作者单位:University of Chicago
摘要:In drug development, replacement of a skeletal carbon with a sulfur atom can result in analogs of bioactive compounds with improved properties. Currently, the sulfur analogs are almost exclusively prepared by de novo synthesis; the existing approach to swap carbon with sulfur is inefficient and involves stoichiometric mercury reagents. In this study, we report a two-step carbonyl-to-sulfur (CO-to-S) atom swap approach, enabled by a rationally designed N '-alkyl-hydrazonamide (NAHA) reagent tha...