8001期

最新文章

• Gender bias is more exaggerated in online images than in text AI翻译
  作者：Hofstra, Bas; Mulders, Anne Maaike
  作者单位：Radboud University Nijmegen
  摘要：A big-data analysis shows that men are starkly over-represented in online images, and that gender bias is stronger in images compared with text. Such images could influence enduring gender biases in our offline lives. Biased images on the Internet could influence beliefs about gender.
• Catching the rays: my part in Morocco's renewable-energy revolution AI翻译
  作者：[Anonymous]
  摘要：Soukaina El Idrissi Faouzi works to optimize the performance of the world's biggest working solar farm.
• Hypoblast from human pluripotent stem cells regulates epiblast development (vol 626, pg 357, 2024) AI翻译
  作者：Okubo, Takumi; Rivron, Nicolas; Kabata, Mio; Masaki, Hideki; Kishimoto, Keiko; Semi, Katsunori; Nakajima-Koyama, May; Kunitomi, Haruko; Kaswandy, Belinda; Sato, Hideyuki; Nakauchi, Hiromitsu; Woltjen, Knut; Saitou, Mitinori; Sasaki, Erika; Yamamoto, Takuya; Takashima, Yasuhiro
• Why reciprocity is common in humans but rare in other animals AI翻译
  作者：Mathew, Sarah
  作者单位：Arizona State University; Arizona State University-Tempe; Arizona State University; Arizona State University-Tempe
• The life and gruesome death of a bog man revealed after 5,000 years AI翻译
  作者：Callaway, Ewen
  摘要：Vittrup Man, who died in his thirties, was a Scandinavian wanderer who settled down between 3300 and 3100 bc.
• Identifying general reaction conditions by bandit optimization AI翻译
  作者：Wang, Jason Y.; Stevens, Jason M.; Kariofillis, Stavros K.; Tom, Mai-Jan; Golden, Dung L.; Li, Jun; Tabora, Jose E.; Parasram, Marvin; Shields, Benjamin J.; Primer, David N.; Hao, Bo; Del Valle, David; Disomma, Stacey; Furman, Ariel; Zipp, G. Greg; Melnikov, Sergey; Paulson, James; Doyle, Abigail G.
  作者单位：Princeton University; University of California System; University of California Los Angeles; Bristol-Myers Squibb; Bristol-Myers Squibb; Johnson & Johnson; Janssen Pharmaceuticals; Bristol-Myers Squibb; Columbia University; New York University; Bristol-Myers Squibb
  摘要：Reaction conditions that are generally applicable to a wide variety of substrates are highly desired, especially in the pharmaceutical and chemical industries1-6. Although many approaches are available to evaluate the general applicability of developed conditions, a universal approach to efficiently discover these conditions during optimizations is rare. Here we report the design, implementation and application of reinforcement learning bandit optimization models7-10 to identify generally appl...
• Protracted neuronal recruitment in the temporal lobes of young children AI翻译
  作者：Nascimento, Marcos Assis; Biagiotti, Sean; Herranz-Perez, Vicente; Santiago, Samara; Bueno, Raymund; Ye, Chun J.; Abel, Taylor J.; Zhang, Zhuangzhi; Rubio-Moll, Juan S.; Kriegstein, Arnold R.; Yang, Zhengang; Garcia-Verdugo, Jose Manuel; Huang, Eric J.; Alvarez-Buylla, Arturo; Sorrells, Shawn F.
  作者单位：University of California System; University of California San Francisco; University of California System; University of California San Francisco; Pennsylvania Commonwealth System of Higher Education (PCSHE); University of Pittsburgh; University of Valencia; CIBERNED; University of Valencia; Pennsylvania Commonwealth System of Higher Education (PCSHE); University of Pittsburgh; Pennsylvania Commonwealth System of Higher Education (PCSHE); University of Pittsburgh; University of California System; University of California San Francisco; University of California System; University of California San Francisco; University of California System; University of California San Francisco; University of California System; University of California San Francisco; Chan Zuckerberg Initiative (CZI); Pennsylvania Commonwealth System of Higher Education (PCSHE); University of Pittsburgh; Fudan University; Fudan University; Hospital Universitari i Politecnic La Fe; University of California System; University of California San Francisco; University of California System; University of California San Francisco
  摘要：The temporal lobe of the human brain contains the entorhinal cortex (EC). This region of the brain is a highly interconnected integrative hub for sensory and spatial information; it also has a key role in episodic memory formation and is the main source of cortical hippocampal inputs1-4. The human EC continues to develop during childhood5, but neurogenesis and neuronal migration to the EC are widely considered to be complete by birth. Here we show that the human temporal lobe contains many you...
• To unravel the origin of life, treat findings as pieces of a bigger puzzle AI翻译
  作者：Lane, Nick; Xavier, Joana C.
  作者单位：University of London; University College London; Imperial College London
  摘要：Explaining isolated steps on the road from simple chemicals to complex living organisms is not enough. Looking at the big picture could help to bridge rifts in this fractured research field.
• On the genetic basis of tail-loss evolution in humans and apes AI翻译
  作者：Xia, Bo; Zhang, Weimin; Zhao, Guisheng; Zhang, Xinru; Bai, Jiangshan; Brosh, Ran; Wudzinska, Aleksandra; Huang, Emily; Ashe, Hannah; Ellis, Gwen; Pour, Maayan; Zhao, Yu; Coelho, Camila; Zhu, Yinan; Miller, Alexander; Dasen, Jeremy S.; Maurano, Matthew T.; Kim, Sang Y.; Boeke, Jef D.; Yanai, Itai
  作者单位：NYU Langone Medical Center; NYU Langone Medical Center; Harvard University; Massachusetts Institute of Technology (MIT); Broad Institute; Harvard University; Pennsylvania Commonwealth System of Higher Education (PCSHE); Pennsylvania State University; Pennsylvania State University - University Park; NYU Langone Medical Center; NYU Langone Medical Center; NYU Langone Medical Center; New York University; New York University Tandon School of Engineering
  摘要：The loss of the tail is among the most notable anatomical changes to have occurred along the evolutionary lineage leading to humans and to the 'anthropomorphous apes'1-3, with a proposed role in contributing to human bipedalism4-6. Yet, the genetic mechanism that facilitated tail-loss evolution in hominoids remains unknown. Here we present evidence that an individual insertion of an Alu element in the genome of the hominoid ancestor may have contributed to tail-loss evolution. We demonstrate t...
• Bone marrow plasma cells require P2RX4 to sense extracellular ATP AI翻译
  作者：Ishikawa, Masaki; Hasanali, Zainul S.; Zhao, Yongge; Das, Arundhoti; Lavaert, Marieke; Roman, Carly J.; Londregan, Jennifer; Allman, David; Bhandoola, Avinash
  作者单位：National Institutes of Health (NIH) - USA; NIH National Cancer Institute (NCI); University of Pennsylvania; University of Pennsylvania
  摘要：Plasma cells produce large quantities of antibodies and so play essential roles in immune protection1. Plasma cells, including a long-lived subset, reside in the bone marrow where they depend on poorly defined microenvironment-linked survival signals1. We show that bone marrow plasma cells use the ligand-gated purinergic ion channel P2RX4 to sense extracellular ATP released by bone marrow osteoblasts through the gap-junction protein pannexin 3 (PANX3). Mutation of Panx3 or P2rx4 each caused de...