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作者:Geremia, Chris; Hamilton, E. William; Merkle, Jerod A.
作者单位:United States Department of the Interior; US National Park Service; Washington & Lee University; University of Wyoming
摘要:Although momentum is building to restore bison across North America, most efforts focus on small, managed herds, leaving unclear how large, migrating herds shape landscapes and whether their effects enhance or degrade ecosystems. We assessed carbon and nitrogen dynamics across the northern Yellowstone ecosystem, where one of the last remaining large migratory populations resides. Bison stabilized net aboveground production while accelerating nitrogen turnover, increasing aboveground nitrogen p...
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作者:Zhang, Yichi; Broberg, Robert; Zhu, Alan; Li, Gushu; Ge, Li; Smith, Jonathan M.; Feng, Liang
作者单位:University of Pennsylvania; University of Pennsylvania; University of Pennsylvania; City University of New York (CUNY) System; College of Staten Island (CUNY); City University of New York (CUNY) System
摘要:Classical and quantum technologies have traditionally been viewed as orthogonal, with classical systems being deterministic and quantum systems inherently probabilistic. This distinction hinders the development of a scalable quantum internet even as the global internet continues expanding. We report a classical-decisive quantum internet architecture in which the integration of quantum information into advanced photonic technologies enables efficient entanglement distribution over a commerciall...
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作者:Frantz, Laurent
作者单位:University of Munich; University of London; Queen Mary University London
摘要:Although horses have played a transformative role in the recent evolution of humans, altering communication, transportation, farming, and warfare, their domestication occurred unexpectedly late, only around 4500 years ago-more than 5000 years after the domestication of pigs, goats, cattle, and sheep. On page 925 of this issue, Liu et al. (1) report using a combination of ancient DNA analysis and experimental work with mouse models to provide new evidence of the biological changes that transfor...
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作者:Raiken, Harper; Stein, Amelie
作者单位:University of Copenhagen
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作者:Yu, Xiaotong; Hu, Yanan; Lim, Hwee Ying; Li, Ziyi; Jaitin, Diego Adhemar; Yang, Katharine; Kong, Wan Ting; Xu, Jiaqian; Bejarano, David Alejandro; Bied, Mathilde; Orliaguet, Lucie; Rengasamy, Gowshika; Chow, Zachary; Lee, Christopher Zhe Wei; Lum, Josephine; Tian, Jing; Zhang, Xiao-Meng; Liu, Honghao; Tan, Shu Wen; Chen, Jinmiao; See, Peter; Loh, Yuin-Han; Malleret, Benoit; Baig, Sonia; Yassin, M. Shabeer M.; Toh, Sue-Anne Ee Shiow; Malissen, Bernard; Fu, Xiujun; Kabashima, Kenji; Ng, Lai Guan; Bleriot, Camille; Liu, Zhaoyuan; Sheng, Lingling; Zheng, Dan-Ning; Qu, Junwen; Venteclef, Nicolas; Su, Bing; Amit, Ido; Schlitzer, Andreas; Angeli, Veronique; Ginhoux, Florent; Chakarov, Svetoslav
作者单位:Shanghai Jiao Tong University; National University of Singapore; National University of Singapore; Weizmann Institute of Science; Agency for Science Technology & Research (A*STAR); A*STAR - Singapore Immunology Network (SIgN); UNICANCER; Gustave Roussy; University of Bonn; Universite Paris Cite; Agency for Science Technology & Research (A*STAR); Agency for Science Technology & Research (A*STAR); A*STAR - Institute of Molecular & Cell Biology (IMCB); National University of Singapore; Institut National de la Sante et de la Recherche Medicale (Inserm); Aix-Marseille Universite; Aix-Marseille Universite; Shanghai Jiao Tong University; Kyoto University; Shanghai Jiao Tong University; Shanghai Jiao Tong University; Shanghai Jiao Tong University; Central South University
摘要:Tissue macrophages reside in anatomically distinct subtissular niches that shape their identity and function. In white adipose tissue (WAT), we identified three macrophage populations with distinct localization, turnover, and phenotypes. Septal adipose tissue macrophages (sATMs), marked by CD209b and lymphatic vessel endothelial hyaluronan receptor 1, were long-lived and positioned in close proximity to adipocyte stem cells (ASCs) within the WAT septum. Within this shared niche, sATMs instruct...
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作者:Li, Guoping; Sun, Lingfei; Xin, Cuiyan; Hao, Tian; Kharel, Prakash; Manning, Aidan C.; O'Connor, Christopher L.; Moore, Henry; Lei, Shuwen; Gokulnath, Priyanka; Yang, Xinyu; Sharma, Ritin; Garcia-Mansfield, Krystine; Pantham, Priyadarshini; Xiao, Chunyang; Wang, Hanna Y.; Chatterjee, Emeli; Yim, Seungbin; Ren, Leo B.; Spanos, Michail; Zhu, Hua; Li, Haobo; Lei, Ji; Markmann, James F.; Laurent, Louise C.; Rossi, John J.; Akeju, Oluwaseun; Sheng, Quanhu; Shah, Ravi V.; Goddard, William A., III; Lowe, Todd M.; Pirrotte, Patrick; Bitzer, Markus; Ivanov, Pavel; Bonventre, Joseph V.; Das, Saumya
作者单位:Harvard University; Harvard Medical School; Harvard University Medical Affiliates; Massachusetts General Hospital; Harvard University; Harvard Medical School; Harvard University Medical Affiliates; Massachusetts General Hospital; Harvard University; Harvard Medical School; Harvard University Medical Affiliates; Brigham & Women's Hospital; Harvard University; Harvard Medical School; Harvard University Medical Affiliates; Brigham & Women's Hospital; University of California System; University of California Santa Cruz; University of Michigan System; University of Michigan; California Institute of Technology; Beijing University of Chinese Medicine; Translational Genomics Research Institute; University of California System; University of California San Diego; University System of Ohio; Ohio State University; University of Pennsylvania; Pennsylvania Medicine; City of Hope; Vanderbilt University; Vanderbilt University; US Department of Veterans Affairs; Veterans Health Administration (VHA); VA Ann Arbor Healthcare System
摘要:Transfer RNA-derived small RNAs (tsRNAs or tDRs) perform a range of cellular functions. Here, we showed that tRNA-Asp-GTC-3 ' tDR, a hypoxia-induced tDR derived from the 3 ' end of tRNA-Asp-GTC, activated autophagic flux in kidney cells and its silencing blocked autophagic flux. Functional gain-/loss-of-function studies in murine kidney disease models demonstrated a substantial renoprotective function of tRNA-Asp-GTC-3 ' tDR. Mechanistically, tRNA-Asp-GTC-3 ' tDR assembled stable G-quadruplex ...
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作者:Yang, Luhua; Li, Shun; Zhang, Ruiyong
作者单位:Chinese Academy of Sciences; Institute of Oceanology, CAS; Shandong University
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作者:Greenbaum, Dov
作者单位:Reichman University; Reichman University; Yale University
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作者:Greenbaum, Dov
作者单位:Reichman University; Reichman University; Yale University
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作者:Hu, Feng; Yang, Gaoyuan; Zheng, Lu-Ming; Liang, Gui-Jie; Wang, Quan-Ming
作者单位:Tsinghua University; Hubei University of Arts & Science
摘要:Determining the atomic structure of nanoparticles (NPs) is critical for understanding their structural evolution and properties. However, controlling the growth of multiply-twinned metal NPs remains challenging because of numerous competing pathways. In this work, we report the synthesis of two giant silver icosahedral nanoclusters, [Ag213(C equivalent to CR1)96]5- and [Ag429Cl24(C equivalent to CR2)150]5- (Ag213 and Ag429, R1 =3,4,5-F3C6H2 and R2 = 4-CF3C6H4), achieved through ligand engineer...