2025

最新文章

• Building materials could store more than 16 billion tonnes of CO2 annually (vol 387, pg 176, 2025) AI翻译
  作者：[Anonymous]
• Enabling evolvability to evolve AI翻译
  作者：Kussell, Edo
  作者单位：New York University; New York University
• Antiviral signaling of a type III CRISPR-associated deaminase AI翻译
  作者：Li, Yutao; Li, Zhaoxing; Yan, Purui; Hua, Chenyang; Kong, Jianping; Wu, Wanqian; Cui, Yurong; Duan, Yan; Li, Shunxiang; Li, Guanglei; Ji, Shunli; Chen, Yijun; Zhao, Yucheng; Yang, Peng; Hu, Chunyi; Lu, Meiling; Chen, Meirong; Xiao, Yibei
  作者单位：China Pharmaceutical University; China Pharmaceutical University; China Pharmaceutical University; China Pharmaceutical University; Hunan University of Chinese Medicine; Nanjing University of Finance & Economics; China Pharmaceutical University; National University of Singapore; National University of Singapore
  摘要：Prokaryotes have evolved diverse defense strategies against viral infection, including foreign nucleic acid degradation by CRISPR-Cas systems and DNA and RNA synthesis inhibition through nucleotide pool depletion. Here, we report an antiviral mechanism of type III CRISPR-Cas-regulated adenosine triphosphate (ATP) depletion in which ATP is converted into inosine triphosphate (ITP) by CRISPR-Cas-associated adenosine deaminase (CAAD) upon activation by either cA(4) or cA(6), followed by hydrolysi...
• Spiro-C(sp3)-atom transfer: Creating rigid three-dimensional structures with Ph2SCN2 AI翻译
  作者：Sun, Qiu; Belting, Jan-Niklas; Hauda, Julian; Tymann, David; Antoni, Patrick W.; Goddard, Richard; Hansmann, Max M.
  作者单位：Dortmund University of Technology; Max Planck Society
  摘要：The introduction of a single C-atom into organic substrates typically results in the formation of flat molecules containing unsaturated C(sp)-centers. Adding a single C(sp(3))-atom surrounded by four sigma-C-C bonds, which opens up the three-dimensional space, is an unresolved problem in synthetic chemistry. We report the synthesis and application of the diazosulfur ylide Ph2S=C=N-2 reagent that combines the reactivity of both sulfur ylides and diazo compounds to create carbon spiro-centers in...
• Flu shot for chickens advances AI翻译
  作者：Brainard, Jeffrey
• Interfacial bonding enhances thermoelectric cooling in 3D-printed materials AI翻译
  作者：Xu, Shengduo; Horta, Sharona; Lawal, Abayomi; Maji, Krishnendu; Lorion, Magali; Ibanez, Maria
  作者单位：Institute of Science & Technology - Austria
  摘要：Thermoelectric coolers (TECs) are pivotal in modern heat management but face limitations in efficiency and manufacturing scalability. We address these challenges by using an extrusion-based 3D printing technique to fabricate high-performance thermoelectric materials. Our ink formulations ensure the integrity of the 3D-printed structure and effective particle bonding during sintering, achieving record-high figure of merit (zT) values of 1.42 for p-type bismuth antimony telluride [(Bi,Sb)(2)Te-3...
• Quantum computing requires high-performance software AI翻译
  作者：Chow, Jerry M.
  作者单位：International Business Machines (IBM); IBM USA
• The perils of labor AI翻译
  作者：Gainty, Caitjan
  作者单位：University of London; King's College London
• ENERGY TECHNOLOGY Sodium batteries power up AI翻译
  作者：Service, Robert F.
• High-performance computing at a crossroads AI翻译
  作者：Deelman, Ewa; Dongarra, Jack; Hendrickson, Bruce; Randles, Amanda; Reed, Daniel; Seidel, Edward; Yelick, Katherine
  作者单位：University of Southern California; University of Tennessee System; University of Tennessee Knoxville; United States Department of Energy (DOE); Oak Ridge National Laboratory; University of Manchester; United States Department of Energy (DOE); Lawrence Livermore National Laboratory; Duke University; Utah System of Higher Education; University of Utah; University of Wyoming; University of California System; University of California Berkeley