8006期

最新文章

• Mitochondrial complex I activity in microglia sustains neuroinflammation AI翻译
  作者：Peruzzotti-Jametti, L.; Willis, C. M.; Krzak, G.; Hamel, R.; Pirvan, L.; Ionescu, R. -b.; Reisz, J. A.; Prag, H. A.; Garcia-Segura, M. E.; Wu, V.; Xiang, Y.; Barlas, B.; Casey, A. M.; van den Bosch, A. M. R.; Nicaise, A. M.; Roth, L.; Bates, G. R.; Huang, H.; Prasad, P.; Vincent, A. E.; Frezza, C.; Viscomi, C.; Balmus, G.; Takats, Z.; Marioni, J. C.; D'Alessandro, A.; Murphy, M. P.; Mohorianu, I.; Pluchino, S.
  作者单位：University of Cambridge; University of Cambridge; Imperial College London; University of Cambridge; University of Colorado System; University of Colorado Anschutz Medical Campus; University of Cambridge; University of Cambridge; Newcastle University - UK; University of Cologne; University of Padua; European Molecular Biology Laboratory (EMBL); European Bioinformatics Institute
  摘要：Sustained smouldering, or low-grade activation, of myeloid cells is a common hallmark of several chronic neurological diseases, including multiple sclerosis1. Distinct metabolic and mitochondrial features guide the activation and the diverse functional states of myeloid cells2. However, how these metabolic features act to perpetuate inflammation of the central nervous system is unclear. Here, using a multiomics approach, we identify a molecular signature that sustains the activation of microgl...
• Adopt universal standards for study adaptation to boost health, education and social-science research AI翻译
  作者：Iliescu, Dragos; Greiff, Samuel
  作者单位：University of Bucharest; Goethe University Frankfurt
  摘要：Letter to the Editor
• HISTORY OF MEDIEVAL MOUNTS - FROM THE HORSE'S MOUTH AI翻译
  作者：[Anonymous]
• The wearable electronic patch that's impervious to sweat AI翻译
  作者：Rao, Yifan; Lu, Nanshu
  作者单位：University of Texas System; University of Texas Austin; University of Texas System; University of Texas Austin; University of Texas System; University of Texas Austin; University of Texas System; University of Texas Austin; University of Texas System; University of Texas Austin
  摘要：A smart adhesive patch that wicks sweat away from electronics embedded in its centre offers comfortable and reliable sensing of the wearer's biometrics or environment without the risk of perspiration damaging the devices.
• A high black-hole-to-host mass ratio in a lensed AGN in the early Universe AI翻译
  作者：Furtak, Lukas J.; Labbe, Ivo; Zitrin, Adi; Greene, Jenny E.; Dayal, Pratika; Chemerynska, Iryna; Kokorev, Vasily; Miller, Tim B.; Goulding, Andy D.; de Graaff, Anna; Bezanson, Rachel; Brammer, Gabriel B.; Cutler, Sam E.; Leja, Joel; Pan, Richard; Price, Sedona H.; Wang, Bingjie; Weaver, John R.; Whitaker, Katherine E.; Atek, Hakim; Bogdan, Akos; Charlot, Stephane; Curtis-Lake, Emma; van Dokkum, Pieter; Endsley, Ryan; Feldmann, Robert; Fudamoto, Yoshinobu; Fujimoto, Seiji; Glazebrook, Karl; Juneau, Stephanie; Marchesini, Danilo; Maseda, Micheal V.; Nelson, Erica; Oesch, Pascal A.; Plat, Adele; Setton, David J.; Stark, Daniel P.; Williams, Christina C.
  作者单位：Ben-Gurion University of the Negev; Swinburne University of Technology; Princeton University; University of Groningen; Kapteyn Astronomical Institute; Sorbonne Universite; Centre National de la Recherche Scientifique (CNRS); Yale University; Northwestern University; Northwestern University; Max Planck Society; Pennsylvania Commonwealth System of Higher Education (PCSHE); University of Pittsburgh; Pennsylvania Commonwealth System of Higher Education (PCSHE); University of Pittsburgh; University of Copenhagen; Niels Bohr Institute; University of Massachusetts System; University of Massachusetts Amherst; Pennsylvania Commonwealth System of Higher Education (PCSHE); Pennsylvania State University; Pennsylvania State University - University Park; Pennsylvania Commonwealth System of Higher Education (PCSHE); Pennsylvania State University; Pennsylvania State University - University Park; Pennsylvania Commonwealth System of Higher Education (PCSHE); Pennsylvania State University; Pennsylvania State University - University Park; Tufts University; Smithsonian Institution; University of Hertfordshire; University of Texas System; University of Texas Austin; University of Zurich; Waseda University; National Institutes of Natural Sciences (NINS) - Japan; National Astronomical Observatory of Japan (NAOJ); University of Wisconsin System; University of Wisconsin Madison; University of Colorado System; University of Colorado Boulder; University of Geneva; University of Arizona
  摘要：Early JWST observations have uncovered a population of red sources that might represent a previously overlooked phase of supermassive black hole growth1-3. One of the most intriguing examples is an extremely red, point-like object that was found to be triply imaged by the strong lensing cluster Abell 2744 (ref. 4). Here we present deep JWST/NIRSpec observations of this object, Abell2744-QSO1. The spectroscopy confirms that the three images are of the same object, and that it is a highly redden...
• FIRST PIG KIDNEY TRANSPLANT IN A PERSON: WHAT IT MEANS FOR THE FUTURE AI翻译
  作者：Mallapaty, Smriti; Kozlov, Max
  摘要：The operation's early success has made researchers hopeful that clinical trials for xenotransplanted organs will start soon.
• Heat flows enrich prebiotic building blocks and enhance their reactivity AI翻译
  作者：Matreux, Thomas; Aikkila, Paula; Scheu, Bettina; Braun, Dieter; Mast, Christof B.
  作者单位：University of Munich; University of Munich
  摘要：The emergence of biopolymer building blocks is a crucial step during the origins of life 1-6 . However, all known formation pathways rely on rare pure feedstocks and demand successive purification and mixing steps to suppress unwanted side reactions and enable high product yields. Here we show that heat flows through thin, crack-like geo-compartments could have provided a widely available yet selective mechanism that separates more than 50 prebiotically relevant building blocks from complex mi...
• Double-side 2D/3D heterojunctions for inverted perovskite solar cells AI翻译
  作者：Azmi, Randi; Utomo, Drajad Satrio; Vishal, Badri; Zhumagali, Shynggys; Dally, Pia; Risqi, Andi Muhammad; Prasetio, Adi; Ugur, Esma; Cao, Fangfang; Imran, Imil Fadli; Said, Ahmed Ali; Pininti, Anil Reddy; Subbiah, Anand Selvin; Aydin, Erkan; Xiao, Chuanxiao; Seok, Sang Il; De Wolf, Stefaan
  作者单位：King Abdullah University of Science & Technology; Ulsan National Institute of Science & Technology (UNIST); Chinese Academy of Sciences; Ningbo Institute of Materials Technology & Engineering, CAS
  摘要：Defects at the top and bottom interfaces of three-dimensional (3D) perovskite photoabsorbers diminish the performance and operational stability of perovskite solar cells owing to charge recombination, ion migration and electric-field inhomogeneities1-5. Here we demonstrate that long alkyl amine ligands can generate near-phase-pure 2D perovskites at the top and bottom 3D perovskite interfaces and effectively resolve these issues. At the rear-contact side, we find that the alkyl amine ligand str...
• Trio of radicals choreographed for versatile chemical reaction AI翻译
  作者：Clark, Kenneth F.; Murphy, John A.
  作者单位：AstraZeneca; University of Strathclyde
• A test for Alzheimer's-disease stage predicts dementia risk AI翻译
  作者：[Anonymous]
  摘要：Levels of a host of molecules in the cerebrospinal fluid reliably assess development of the disease.