8017期

最新文章

• Father's diet influences son's metabolic health AI翻译
  作者：Cai, Chen; Chen, Qi
  作者单位：Utah System of Higher Education; University of Utah; Utah System of Higher Education; University of Utah
• CERNs $17-billion supercollider in question as top funder criticizes cost AI翻译
  作者：Castelvecchi, Davide
  摘要：Germany has raised doubts about the affordability of the Large Hadron Collider's planned successor.
• The climate crisis is solvable, but human rights must trump profits AI翻译
  作者：Otto, Friederike
  作者单位：Imperial College London
  摘要：Huge planetary problems were fixed in the past, yielding lessons for the current climate crisis - yet this time a solution is justice.
• Remember the 'human' in human neuroscience AI翻译
  作者：[Anonymous]
• Mental navigation in the primate entorhinal cortex AI翻译
  作者：Neupane, Sujaya; Fiete, Ila; Jazayeri, Mehrdad
  作者单位：Massachusetts Institute of Technology (MIT); Massachusetts Institute of Technology (MIT)
  摘要：A cognitive map is a suitably structured representation that enables novel computations using previous experience; for example, planning a new route in a familiar space1. Work in mammals has found direct evidence for such representations in the presence of exogenous sensory inputs in both spatial2,3 and non-spatial domains4-10. Here we tested a foundational postulate of the original cognitive map theory1,11: that cognitive maps support endogenous computations without external input. We recorde...
• Selective haematological cancer eradication with preserved haematopoiesis AI翻译
  作者：Garaude, Simon; Marone, Romina; Lepore, Rosalba; Devaux, Anna; Beerlage, Astrid; Seyres, Denis; Dell' Aglio, Alessandro; Juskevicius, Darius; Zuin, Jessica; Burgold, Thomas; Wang, Sisi; Katta, Varun; Manquen, Garret; Li, Yichao; Larrue, Clement; Camus, Anna; Durzynska, Izabela; Wellinger, Lisa C.; Kirby, Ian; Van Berkel, Patrick H.; Kunz, Christian; Tamburini, Jerome; Bertoni, Francesco; Widmer, Corinne C.; Tsai, Shengdar Q.; Simonetta, Federico; Urlinger, Stefanie; Jeker, Lukas T.
  作者单位：University of Basel; University of Basel; University of Basel; University of Basel; University of Basel; University of Geneva; St Jude Children's Research Hospital; University of Geneva; Institute of Oncology Research (IOR); Universita della Svizzera Italiana; Institute of Oncology Research (IOR); University of Basel; Institut National de la Sante et de la Recherche Medicale (Inserm); Centre National de la Recherche Scientifique (CNRS); Universite de Toulouse; Universite Toulouse III - Paul Sabatier
  摘要：Haematopoietic stem cell (HSC) transplantation (HSCT) is the only curative treatment for a broad range of haematological malignancies, but the standard of care relies on untargeted chemotherapies and limited possibilities to treat malignant cells after HSCT without affecting the transplanted healthy cells(1). Antigen-specific cell-depleting therapies hold the promise of much more targeted elimination of diseased cells, as witnessed in the past decade by the revolution of clinical practice for ...
• 'Fighting fire with fire' - using LLMs to combat LLM hallucinations AI翻译
  作者：Verspoor, Karin
  作者单位：Royal Melbourne Institute of Technology (RMIT); University of Melbourne
  摘要：The number of errors produced by an LLM can be reduced by grouping its outputs into semantically similar clusters. Remarkably, this task can be performed by a second LLM, and the method's efficacy can be evaluated by a third. Confabulations detected by clustering semantically similar LLM responses.
• A virally encoded high-resolution screen of cytomegalovirus dependencies AI翻译
  作者：Finkel, Yaara; Nachshon, Aharon; Aharon, Einav; Arazi, Tamar; Simonovsky, Elena; Dobesova, Martina; Saud, Zack; Gluck, Avi; Fisher, Tal; Stanton, Richard J.; Schwartz, Michal; Stern-Ginossar, Noam
  作者单位：Weizmann Institute of Science; Cardiff University
  摘要：Genetic screens have transformed our ability to interrogate cellular factor requirements for viral infections(1,2), but most current approaches are limited in their sensitivity, biased towards early stages of infection and provide only simplistic phenotypic information that is often based on survival of infected cells(2-4). Here, by engineering human cytomegalovirus to express single guide RNA libraries directly from the viral genome, we developed virus-encoded CRISPR-based direct readout scre...
• AGAINST THE GRAIN: CRISPR USED TO IMPROVE RICE PLANT AI翻译
  作者：[Anonymous]
• Reproducible graphene synthesis by oxygen-free chemical vapour deposition AI翻译
  作者：Amontree, Jacob; Yan, Xingzhou; DiMarco, Christopher S.; Levesque, Pierre L.; Adel, Tehseen; Pack, Jordan; Holbrook, Madisen; Cupo, Christian; Wang, Zhiying; Sun, Dihao; Biacchi, Adam J.; Wilson-Stokes, Charlezetta E.; Watanabe, Kenji; Taniguchi, Takashi; Dean, Cory R.; Hight Walker, Angela R.; Barmak, Katayun; Martel, Richard; Hone, James
  作者单位：Columbia University; Universite de Montreal; Universite de Montreal; National Institute of Standards & Technology (NIST) - USA; Columbia University; National Institute of Standards & Technology (NIST) - USA; Howard University; National Institute for Materials Science; Columbia University
  摘要：Chemical vapour deposition (CVD) synthesis of graphene on copper has been broadly adopted since the first demonstration of this process(1). However, widespread use of CVD-grown graphene for basic science and applications has been hindered by challenges with reproducibility(2) and quality(3). Here we identify trace oxygen as a key factor determining the growth trajectory and quality for graphene grown by low-pressure CVD. Oxygen-free chemical vapour deposition (OF-CVD) synthesis is fast and hig...