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作者:Cai, Chen; Chen, Qi
作者单位:Utah System of Higher Education; University of Utah; Utah System of Higher Education; University of Utah
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作者:Castelvecchi, Davide
摘要:Germany has raised doubts about the affordability of the Large Hadron Collider's planned successor.
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作者:Otto, Friederike
作者单位:Imperial College London
摘要:Huge planetary problems were fixed in the past, yielding lessons for the current climate crisis - yet this time a solution is justice.
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作者:[Anonymous]
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作者:Neupane, Sujaya; Fiete, Ila; Jazayeri, Mehrdad
作者单位:Massachusetts Institute of Technology (MIT); Massachusetts Institute of Technology (MIT)
摘要:A cognitive map is a suitably structured representation that enables novel computations using previous experience; for example, planning a new route in a familiar space1. Work in mammals has found direct evidence for such representations in the presence of exogenous sensory inputs in both spatial2,3 and non-spatial domains4-10. Here we tested a foundational postulate of the original cognitive map theory1,11: that cognitive maps support endogenous computations without external input. We recorde...
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作者:Garaude, Simon; Marone, Romina; Lepore, Rosalba; Devaux, Anna; Beerlage, Astrid; Seyres, Denis; Dell' Aglio, Alessandro; Juskevicius, Darius; Zuin, Jessica; Burgold, Thomas; Wang, Sisi; Katta, Varun; Manquen, Garret; Li, Yichao; Larrue, Clement; Camus, Anna; Durzynska, Izabela; Wellinger, Lisa C.; Kirby, Ian; Van Berkel, Patrick H.; Kunz, Christian; Tamburini, Jerome; Bertoni, Francesco; Widmer, Corinne C.; Tsai, Shengdar Q.; Simonetta, Federico; Urlinger, Stefanie; Jeker, Lukas T.
作者单位:University of Basel; University of Basel; University of Basel; University of Basel; University of Basel; University of Geneva; St Jude Children's Research Hospital; University of Geneva; Institute of Oncology Research (IOR); Universita della Svizzera Italiana; Institute of Oncology Research (IOR); University of Basel; Institut National de la Sante et de la Recherche Medicale (Inserm); Centre National de la Recherche Scientifique (CNRS); Universite de Toulouse; Universite Toulouse III - Paul Sabatier
摘要:Haematopoietic stem cell (HSC) transplantation (HSCT) is the only curative treatment for a broad range of haematological malignancies, but the standard of care relies on untargeted chemotherapies and limited possibilities to treat malignant cells after HSCT without affecting the transplanted healthy cells(1). Antigen-specific cell-depleting therapies hold the promise of much more targeted elimination of diseased cells, as witnessed in the past decade by the revolution of clinical practice for ...
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作者:Verspoor, Karin
作者单位:Royal Melbourne Institute of Technology (RMIT); University of Melbourne
摘要:The number of errors produced by an LLM can be reduced by grouping its outputs into semantically similar clusters. Remarkably, this task can be performed by a second LLM, and the method's efficacy can be evaluated by a third. Confabulations detected by clustering semantically similar LLM responses.
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作者:Finkel, Yaara; Nachshon, Aharon; Aharon, Einav; Arazi, Tamar; Simonovsky, Elena; Dobesova, Martina; Saud, Zack; Gluck, Avi; Fisher, Tal; Stanton, Richard J.; Schwartz, Michal; Stern-Ginossar, Noam
作者单位:Weizmann Institute of Science; Cardiff University
摘要:Genetic screens have transformed our ability to interrogate cellular factor requirements for viral infections(1,2), but most current approaches are limited in their sensitivity, biased towards early stages of infection and provide only simplistic phenotypic information that is often based on survival of infected cells(2-4). Here, by engineering human cytomegalovirus to express single guide RNA libraries directly from the viral genome, we developed virus-encoded CRISPR-based direct readout scre...
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作者:[Anonymous]
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作者:Amontree, Jacob; Yan, Xingzhou; DiMarco, Christopher S.; Levesque, Pierre L.; Adel, Tehseen; Pack, Jordan; Holbrook, Madisen; Cupo, Christian; Wang, Zhiying; Sun, Dihao; Biacchi, Adam J.; Wilson-Stokes, Charlezetta E.; Watanabe, Kenji; Taniguchi, Takashi; Dean, Cory R.; Hight Walker, Angela R.; Barmak, Katayun; Martel, Richard; Hone, James
作者单位:Columbia University; Universite de Montreal; Universite de Montreal; National Institute of Standards & Technology (NIST) - USA; Columbia University; National Institute of Standards & Technology (NIST) - USA; Howard University; National Institute for Materials Science; Columbia University
摘要:Chemical vapour deposition (CVD) synthesis of graphene on copper has been broadly adopted since the first demonstration of this process(1). However, widespread use of CVD-grown graphene for basic science and applications has been hindered by challenges with reproducibility(2) and quality(3). Here we identify trace oxygen as a key factor determining the growth trajectory and quality for graphene grown by low-pressure CVD. Oxygen-free chemical vapour deposition (OF-CVD) synthesis is fast and hig...